Results 21 to 30 of about 44,426 (335)

COX-2-derived prostanoids and oxidative stress additionally reduce endothelium-mediated relaxation in old type 2 diabetic rats. [PDF]

open access: yesPLoS ONE, 2013
Endothelial dysfunction in resistance arteries alters end organ perfusion in type 2 diabetes. Superoxides and cyclooxygenase-2 (COX-2) derivatives have been shown separately to alter endothelium-mediated relaxation in aging and diabetes but their role in
Emilie Vessières   +6 more
doaj   +1 more source

Pathobiochemical pathways of redox imbalance in the neurological long-term effects of COVID-19 and the role of chondroitin sulfate in the redox status restoration

open access: yesНеврология, нейропсихиатрия, психосоматика, 2021
The review examines the epidemiology and clinical manifestations of COVID-19 long-term neurological effects, main pathobiochemical mechanisms, and integrated circuits of redox status impairment in COVID-19, such as the decrease of adenosine triphosphate ...
I. V. Sarvilina   +2 more
doaj   +1 more source

Prevention of cisplatin-induced hearing loss in children: achievements and challenges for evidence-based implementation of sodium Thiosulfate. [PDF]

open access: yesFront Oncol
Ototoxicity is a devastating direct, irreversible side effect of platinum use in children with cancer, with its consequent effect on speech, language and social development, quality of life and adult productivity. Cisplatin, an essential chemotherapeutic
Meijer AJM   +3 more
europepmc   +2 more sources

Catalytically active gold clusters with atomic precision for noninvasive early intervention of neurotrauma

open access: yesJournal of Nanobiotechnology, 2021
Background Neurotrauma is a worldwide public health problem which can be divided into primary and secondary damge. The primary damge is caused by external forces and triggers the overproduction of peroxides and superoxides, leading to long-lasting ...
Yunguang Zhang   +8 more
doaj   +1 more source

Antiradical and antiulcer effect of Sonneratia apetala Buch-Ham leaves against alcohol induced gastric mucosal injury

open access: yesArs Pharmaceutica, 2021
Introduction: Sonneratia apetala Buch-Ham is a true mangrove inhabitant in Indian Sunderban and it is used in folk medicine for digestive disorders. Method: Hydro-methanolic (20:80) extract of Sonneratia apetala leaves (SA) was chemically standardized
Avijit Hazra   +3 more
doaj   +1 more source

Metallic Aluminum Suboxides with Ultrahigh Electrical Conductivity at High Pressure

open access: yesResearch, 2022
Aluminum, as the most abundant metallic elemental content in the Earth’s crust, usually exists in the form of alumina (Al2O3). However, the oxidation state of aluminum and the crystal structures of aluminum oxides in the pressure range of planetary ...
Tianheng Huang   +9 more
doaj   +1 more source

Antifungal Action of Arabidopsis thaliana TCP21 via Induction of Oxidative Stress and Apoptosis

open access: yesAntioxidants, 2023
The realm of antimicrobial proteins in plants is extensive but remains relatively uncharted. Understanding the mechanisms underlying the action of plant antifungal proteins (AFPs) holds promise for antifungal strategies.
Seong-Cheol Park   +4 more
doaj   +1 more source

Isorhamnetin Influences the Viability, Superoxide Production and Interleukin-8 Biosynthesis of Human Colorectal Adenocarcinoma HT-29 Cells In Vitro

open access: yesLife, 2023
Isorhamnetin has gained research interest for its anti-inflammatory, anti-proliferative and chemoprotective properties. In this study, human colon adenocarcinoma cells were cultured in the presence or absence of different isorhamnetin concentrations (5 ...
Hana Greifová   +9 more
doaj   +1 more source

Key problems of the four-dimensional Earth system

open access: yesMatter and Radiation at Extremes, 2020
Compelling evidence indicates that the solid Earth consists of two physicochemically distinct zones separated radially in the middle of the lower mantle at ∼1800 km depth.
Ho-kwang Mao, Wendy L. Mao
doaj   +1 more source

Nickel-gallate metal–organic framework as an efficient antimicrobial and anticancer agent: in vitro study

open access: yesCancer Nanotechnology, 2023
Gallic acid is a natural antioxidant present in many plants such as tea, sumac, gallnut and other plants. This naturally occurring gallic acid is known to exhibit auto-oxidation under certain conditions, generating several reactive oxygen species (ROS ...
Ahmed. A. G. El-Shahawy   +4 more
doaj   +1 more source

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