Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
The role of perceived supervisor support and perceived organisational support on organisational citizenship behaviour in auxiliary police services at a public university: a pilot study [PDF]
Organizational citizenship behavior refers to voluntary actions that are not part of official duties and are not directly rewarded, but can increase the effectiveness of functions in the organization, such as helping colleagues and participating in extra
Ramdan, Mohamad Rohieszan +5 more
core +1 more source
The need to be unique and the innovative behavior: The moderating role of supervisor support. [PDF]
Front Psychol, 2022 Bekmezci M +4 more
europepmc +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Uniform Interstate Family Support Act Ohio
, 1999 Title from cover of PDF document (viewed Nov. 21, 2005); responsibility statement from p. 2 of cover.; "Created: 6/11/1999 ...; Modified: 8/24/1999 ..."--Document properties screen.; Harvested from the web on 11/21 ...
Center for the Support of Families.
core
Psychological Distress, Japanese Teleworkers, and Supervisor Support During COVID-19. [PDF]
J Occup Environ Med, 2023 Kikunaga K +10 more
europepmc +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Who stay unwillingly in a job? [PDF]
The paper examines the antecedents of intentions to quit, job search, and actual job switches during a five-year follow-up period. We use a representative random sample of all Finnish employees (N = 2800).
Böckerman, Petri +3 more
core
Unlocking deflection: The role of supervisor support in police officer willingness to refer people who inject drugs to harm reduction services. [PDF]
Int J Drug Policy, 2023 Marotta PL +9 more
europepmc +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source