Results 71 to 80 of about 5,588,542 (410)

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Corporate social responsibility in buyer-supplier relationships : is it beneficial for top-tier suppliers to market their capability to ensure a responsible supply chain? [PDF]

The Retail and Marketing Review, 2014
This study assesses how top-tier suppliers market their capabilities to ensure a responsible upstream sup- ply chain to their downstream buyers, and how the marketing of corporate social responsibility (CSR)- related supply management practices affects ...
T Leppelt, K Foerstl, E Hartmann
doaj  

Segmentation of health-care consumers: psychological determinants of subjective health and other person-related variables

BMC Health Services Research, 2020
Background There is an observable, growing trend toward tailoring support programs – in addition to medical treatment – more closely to individuals to help improve patients’ health status.
Sjaak Bloem, Joost Stalpers, Edward A. G. Groenland, Kees van Montfort, W. Fred van Raaij, Karla de Rooij   +5 more
doaj   +1 more source

Cold Supply Chain Planning including Smart Contracts: An Intelligent Blockchain-based approach [PDF]

arXiv, 2022
Vaccinating the global population against Covid-19 is one of the biggest supply chain management challenges humanity has ever faced. Rapid supply of Covid-19 vaccines is essential for successful global immunization, but its effectiveness depends on a transparent supply chain that can be monitored. In this research, we have proposed an approach based on
arxiv  

Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells

FEBS Letters, EarlyView.
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga, Kazuki Harada, Takuya Yamauchi, Tetsuya Kitaguchi, Masami Yokota Hirai, Mitsuharu Matsumoto, Takashi Tsuboi   +6 more
wiley   +1 more source

Forecast accuracy in demand planning: A fast-moving consumer goods case study

Journal of Transport and Supply Chain Management, 2019
Background: An established South African fast-moving consumer goods (FMCG) manufacturer, Company A, sought to address an underperforming supply chain through an attempt to improve demand planning accuracy.
Lisa M. Basson, Peter J. Kilbourn, Jackie Walters   +2 more
doaj   +1 more source

Integrating On-chain and Off-chain Governance for Supply Chain Transparency and Integrity [PDF]

Proc. 5th Symp. Distributed Ledger Technology, Brisbane, Australia, 23 Nov 2021, 2021
Integrating on-chain and off-chain data storage for decentralised and distributed information systems, such as blockchain, presents specific challenges for providing transparency of data governance and ensuring data integrity through stakeholder engagement.
arxiv  

Impact of Internal Integration, Supply Chain Partnership, Supply Chain Agility, and Supply Chain Resilience on Sustainable Advantage

Sustainability, 2021
The global order has suddenly changed due to the COVID-19 pandemic. Many countries, including Indonesia, have applied lockdown policies to stop the spread of COVID-19.
Z. Tarigan, H. Siagian, F. Jie
semanticscholar   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Cross-departmental collaboration in strategic sourcing as a catalyst for supplier development: The case of Eskom

Acta Commercii, 2017
Objective: The objective was to analyse the integration of and collaboration between strategic sourcing and supplier development at Eskom, South Africa’s primary electricity supplier, and to determine how strategic sourcing can be a catalyst for supplier
Mzoxolo E. Mbiko, Tatenda Mbara, Elana Swanepoel   +2 more
doaj   +1 more source