Results 161 to 170 of about 8,443,769 (248)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

An optimized protocol for efficient derivation of pancreatic islets from multiple human pluripotent stem cell lines

The success of cell therapy for type 1 diabetes (T1D) depends on reliable differentiation of stem cells into functional pancreatic islets. Current protocols produce stem cell-derived islets (SC-islets) that contain non-endocrine cells and show limited ...
Efstathopoulos, Paschalis, Bryzgalova, Galyna, Zhao, Cheng, Lanner, Fredrik, Blust, Kelly, Hedhammar, My, Wu, Siqin, Berggren, Per Olof, Falk, Anna, Erbil, Eda, Chandel, Shivam, Efstathopoulos, P, Bryzgalova, Galyna,, Falk, A,, Falk, Anna,, Zhao, C,, Erbil, E, Berggren, Per Olof,, Zhao, Cheng,, Lanner, Fredrik,, Blust, Kelly,, Hedhammar, M, Bryzgalova, G,, Wu, S, Berggren, P-O, Wu, Siqin,, Chandel, S,, Hedhammar, My,, Blust, K, Chandel, Shivam,, Erbil, Eda,, Efstathopoulos, Paschalis,, Lund University.   +32 more
core   +1 more source

Organ of Corti macrophages: a distinct group of cochlear macrophages with potential roles in supporting cell degeneration and survival. [PDF]

Front Immunol
Ye M, Zhang C, Ding D, Chen GD, Adler HJ, Sharaf R, Hu BH.   +6 more
europepmc   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Green Minimalistic Approach to Synthesize Chitosan-Based Durable Polymer Hydrogel Materials for Supporting Cell Growth. [PDF]

Gels
Pawlik J, Borawska K, Wieczorek P, Kamiński K.   +3 more
europepmc   +1 more source

Dibenzazepine promotes cochlear supporting cell proliferation and hair cell regeneration in neonatal mice. [PDF]

Cell Prolif, 2020
Wu J, Dong X, Li W, Zhao L, Zhou L, Sun S, Li H.   +6 more
europepmc   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Supporting cell involvement in cochlear damage and repair: Novel insights from a quantitative analysis of cyclodextrin-induced ototoxicity in mice. [PDF]

Hear Res
Ding D, Chen GD, Zhang C, Ye M, Adler HJ, Sharaf R, Naldrett K, Mittal T, Hu BH.   +8 more
europepmc   +1 more source

Supporting Cell-Based Tendon Therapy: Effect of PDGF-BB and Ascorbic Acid on Rabbit Achilles Tenocytes in Vitro. [PDF]

Int J Mol Sci, 2020
Evrova O, Kellenberger D, Calcagni M, Vogel V, Buschmann J.   +4 more
europepmc   +1 more source