Correction to: Knockdown of Foxg1 in supporting cells increases the trans‑differentiation of supporting cells into hair cells in the neonatal mouse cochlea [PDF]
Shasha Zhang +16 more
doaj +2 more sources
Cochlear supporting cells require GAS2 for cytoskeletal architecture and hearing. [PDF]
Chen T +17 more
europepmc +2 more sources
AstroSat science support cell [PDF]
AstroSat is India's first dedicated multi-wavelength space observatory launched by the Indian Space Research Organisation (ISRO) on 28 September 2015. After launch, the AstroSat Science Support Cell (ASSC) was set up as a joint venture of ISRO and the Inter-University Centre for Astronomy and Astrophysics (IUCAA) with the primary purpose of ...
J. Roy +9 more
openaire +2 more sources
Selection of viral capsids and promoters affects the efficacy of rescue of Tmprss3-deficient cochlea
Adeno-associated virus (AAV)-mediated gene transfer has shown promise in rescuing mouse models of genetic hearing loss, but how viral capsid and promoter selection affects efficacy is poorly characterized.
Ksenia A. Aaron +11 more
doaj +1 more source
The Role of Supporting Cell Populations in Satellite Cell Mediated Muscle Repair
Skeletal muscle has a high capacity to repair and remodel in response to damage, largely through the action of resident muscle stem cells, termed satellite cells.
Amanda L. Johnson +2 more
doaj +1 more source
Hear, Hear for Notch: Control of Cell Fates in the Inner Ear by Notch Signaling
The vertebrate inner ear is responsible for detecting sound, gravity, and head motion. These mechanical forces are detected by mechanosensitive hair cells, arranged in a series of sensory patches in the vestibular and cochlear regions of the ear.
Rogers Brown, Andrew K. Groves
doaj +1 more source
Telocytes: Supporting cells participating in ventricular arrhythmogenesis? [PDF]
Yung‐Kuo Lin, Yi‐Jen Chen
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mTOR Signaling in BDNF-Treated Guinea Pigs after Ototoxic Deafening
The mammalian target of rapamycin (mTOR) signaling plays a critical role in cell homeostasis, growth and survival. Here, we investigated the localization of the main mTOR signaling proteins in the organ of Corti of normal-hearing and deafened guinea pigs,
Annamaria Tisi +4 more
doaj +1 more source
MECOM promotes supporting cell proliferation and differentiation in cochlea
Permanent damage to hair cells (HCs) is the leading cause of sensory deafness. Supporting cells (SCs) are essential in the restoration of hearing in mammals because they can proliferate and differentiate to HCs.
Peipei Chen +7 more
doaj +1 more source
Making sense of Wnt signaling – linking hair cell regeneration to development
Wnt signaling is a highly conserved pathway crucial for development and homeostasis of multicellular organisms. Secreted Wnt ligands bind Frizzled receptors to regulate diverse processes such as axis patterning, cell division, and cell fate specification.
Lina eJansson, Grace eKim, Alan G Cheng
doaj +1 more source

