Results 11 to 20 of about 1,595,147 (255)

Correction to: Knockdown of Foxg1 in supporting cells increases the trans‑differentiation of supporting cells into hair cells in the neonatal mouse cochlea [PDF]

open access: yesCellular and Molecular Life Sciences
Shasha Zhang   +16 more
doaj   +2 more sources

Cochlear supporting cells require GAS2 for cytoskeletal architecture and hearing. [PDF]

open access: yesDev Cell, 2021
Chen T   +17 more
europepmc   +2 more sources

AstroSat science support cell [PDF]

open access: yesJournal of Astrophysics and Astronomy, 2021
AstroSat is India's first dedicated multi-wavelength space observatory launched by the Indian Space Research Organisation (ISRO) on 28 September 2015. After launch, the AstroSat Science Support Cell (ASSC) was set up as a joint venture of ISRO and the Inter-University Centre for Astronomy and Astrophysics (IUCAA) with the primary purpose of ...
J. Roy   +9 more
openaire   +2 more sources

Selection of viral capsids and promoters affects the efficacy of rescue of Tmprss3-deficient cochlea

open access: yesMolecular Therapy: Methods & Clinical Development, 2023
Adeno-associated virus (AAV)-mediated gene transfer has shown promise in rescuing mouse models of genetic hearing loss, but how viral capsid and promoter selection affects efficacy is poorly characterized.
Ksenia A. Aaron   +11 more
doaj   +1 more source

The Role of Supporting Cell Populations in Satellite Cell Mediated Muscle Repair

open access: yesCells, 2023
Skeletal muscle has a high capacity to repair and remodel in response to damage, largely through the action of resident muscle stem cells, termed satellite cells.
Amanda L. Johnson   +2 more
doaj   +1 more source

Hear, Hear for Notch: Control of Cell Fates in the Inner Ear by Notch Signaling

open access: yesBiomolecules, 2020
The vertebrate inner ear is responsible for detecting sound, gravity, and head motion. These mechanical forces are detected by mechanosensitive hair cells, arranged in a series of sensory patches in the vestibular and cochlear regions of the ear.
Rogers Brown, Andrew K. Groves
doaj   +1 more source

mTOR Signaling in BDNF-Treated Guinea Pigs after Ototoxic Deafening

open access: yesBiomedicines, 2022
The mammalian target of rapamycin (mTOR) signaling plays a critical role in cell homeostasis, growth and survival. Here, we investigated the localization of the main mTOR signaling proteins in the organ of Corti of normal-hearing and deafened guinea pigs,
Annamaria Tisi   +4 more
doaj   +1 more source

MECOM promotes supporting cell proliferation and differentiation in cochlea

open access: yesJournal of Otology, 2022
Permanent damage to hair cells (HCs) is the leading cause of sensory deafness. Supporting cells (SCs) are essential in the restoration of hearing in mammals because they can proliferate and differentiate to HCs.
Peipei Chen   +7 more
doaj   +1 more source

Making sense of Wnt signaling – linking hair cell regeneration to development

open access: yesFrontiers in Cellular Neuroscience, 2015
Wnt signaling is a highly conserved pathway crucial for development and homeostasis of multicellular organisms. Secreted Wnt ligands bind Frizzled receptors to regulate diverse processes such as axis patterning, cell division, and cell fate specification.
Lina eJansson, Grace eKim, Alan G Cheng
doaj   +1 more source

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