Results 1 to 10 of about 78 (77)
The suprachiasmatic nucleus [PDF]
Current Biology, 2018 Like it or not, your two suprachiasmatic nuclei (SCN) govern your life: from when you wake up and fall asleep, to when you feel hungry or can best concentrate. Each is composed of approximately 10,000 tightly interconnected neurons, and the pair sit astride the mid-line third ventricle of the hypothalamus, immediately dorsal to the optic chiasm (Figure
Michael H. Hastings, Andrew P. Patton
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An enlarged suprachiasmatic nucleus in homosexual men [PDF]
Brain Research, 1990 Morphometric analysis of the human hypothalamus revealed that the volume of the suprachiasmatic nucleus (SCN) in homosexual men is 1.7 times as large as that of a reference group of male subjects and contains 2.1 times as many cells. In another hypothalamic nucleus which is located in the immediate vicinity of the SCN, the sexually dimorphic nucleus ...
Dick F. Swaab, Michel A. Hofman
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Seasonal changes in the suprachiasmatic nucleus of man [PDF]
Neuroscience Letters, 1992 The mammalian suprachiasmatic nucleus (SCN) is considered to be the principal component of the biological clock, generating a wide variety of physiological and behavioral circadian rhythms. In addition to its implication in circadian rhythms, the SCN is also involved in the expression of some seasonal cycles.
Dick F. Swaab, Michel A. Hofman
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Excitatory Actions of GABA in the Suprachiasmatic Nucleus [PDF]
The Journal of Neuroscience, 2008 Neurons in the suprachiasmatic nucleus (SCN) are responsible for the generation of circadian oscillations, and understanding how these neurons communicate to form a functional circuit is a critical issue. The neurotransmitter GABA and its receptors are widely expressed in the SCN where they mediate cell-to-cell communication.
Hee Joo Choi +13 more
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Vasopressin casts light on the suprachiasmatic nucleus [PDF]
The Journal of Physiology, 2017 Key points A subpopulation of retinal ganglion cells expresses the neuropeptide vasopressin. These retinal ganglion cells project predominately to our biological clock, the suprachiasmatic nucleus (SCN). Light‐induced vasopressin release enhances the responses of SCN neurons to light.
Takahiro Tsuji +10 more
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Functional network inference of the suprachiasmatic nucleus [PDF]
Proceedings of the National Academy of Sciences, 2016 Significance In mammals, circadian rhythms are controlled by a network of neurons in the brain. The structure of this network dictates organism-wide behavior and adaptation to the environment. We used a neurotoxin to desynchronize this circadian network and then used tools from information theory to determine which cells communicate to ...
John H. Abel +11 more
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The Suprachiasmatic Nucleus, Circadian Clocks, and the Liver [PDF]
Diabetes, 2013 The circadian clock system adapts phasic physiological activities, such as sleeping and eating, to environmental cycles. The “master clock” is in the suprachiasmatic nucleus (SCN) and the principal cue (Zeitgeber) is the light–dark cycle, around which most mammalian (and those of all living organisms) functions have evolved.
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Circadian actions of melatonin at the suprachiasmatic nucleus [PDF]
Behavioural Brain Research, 1995 The biological clock in the suprachiasmatic nucleus (SCN) of the hypothalamus plays a well-defined role in regulating melatonin production by the pineal. Emerging evidence indicates that melatonin itself can feed back upon the SCN and thereby influence circadian functions.
Angela J. McArthur, Martha U. Gillette
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Electrophysiological Approaches to Studying the Suprachiasmatic Nucleus
, 2020 In mammals, the part of the nervous system responsible for most circadian behavior can be localized to a bilaterally paired structure in the hypothalamus known as the suprachiasmatic nucleus (SCN). Understanding the mammalian circadian system will require a detailed multilevel analysis of neural SCN circuits ex vivo and in vivo.
Michel, Stephan +3 more
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Calretinin Neurons in the Rat Suprachiasmatic Nucleus [PDF]
Journal of Biological Rhythms, 2016 The hypothalamic suprachiasmatic nucleus (SCN), a circadian pacemaker, is present in all mammalian brains. It has a complex organization of peptide-containing neurons that is similar among species, but calcium-binding proteins are expressed variably.
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