Results 21 to 30 of about 36,798 (270)

The Deubiquitinase USP2 Modulates Photic Entrainment of the Circadian Clock at the Level of the Suprachiasmatic Nucleus. [PDF]

J Neurochem
Srikanta SB, Brown TW, Malescot A, Cloutier MÈ, Zhu L, Coutanson C, Malki M, Storch KF, Rungta R, Cayouette M, Dkhissi-Benyahya O, Cermakian N.   +11 more
europepmc   +3 more sources

Zinc finger homeobox-3 (ZFHX3) orchestrates genome-wide daily gene expression in the suprachiasmatic nucleus. [PDF]

Elife
Bafna A, Banks G, Vasilyev V, Dallmann R, Hastings MH, Nolan PM.   +5 more
europepmc   +2 more sources

The suprachiasmatic nucleus [PDF]

Current Biology, 2018
Like it or not, your two suprachiasmatic nuclei (SCN) govern your life: from when you wake up and fall asleep, to when you feel hungry or can best concentrate. Each is composed of approximately 10,000 tightly interconnected neurons, and the pair sit astride the mid-line third ventricle of the hypothalamus, immediately dorsal to the optic chiasm (Figure
Andrew P, Patton, Michael H, Hastings
openaire   +2 more sources

Circadian neurons in the paraventricular nucleus entrain and sustain daily rhythms in glucocorticoids

Nature Communications, 2021
It is unclear how circadian signals from the suprachiasmatic nucleus (SCN) are decoded to generate daily rhythms in hormone release. Here, the authors show that daily corticosterone release depends on coordinated clock gene and neuronal activity rhythms ...
Jeff R. Jones, Sneha Chaturvedi, Daniel Granados-Fuentes, Erik D. Herzog   +3 more
doaj   +1 more source

A Journey in the Brain’s Clock: In Vivo Veritas?

Biology, 2023
The suprachiasmatic nuclei (SCN) of the hypothalamus contain the circadian pacemaker that coordinates mammalian rhythms in tune with the day-night cycle.
Alec J. Davidson, Delaney Beckner, Xavier Bonnefont   +2 more
doaj   +1 more source

Long-lasting effects of sepsis on circadian rhythms in the mouse. [PDF]

PLoS ONE, 2012
Daily patterns of activity and physiology are termed circadian rhythms and are driven primarily by an endogenous biological timekeeping system, with the master clock located in the suprachiasmatic nucleus.
Emma K O'Callaghan, Sean T Anderson, Paul N Moynagh, Andrew N Coogan   +3 more
doaj   +1 more source

Ablation of microglia does not alter circadian rhythm of locomotor activity

Molecular Brain, 2023
Microglia, as macrophages in the brain, are responsible for immune responses and synaptic remodeling. Although the function of microglia is regulated by circadian rhythms, it is still unclear whether microglia are involved in the generation and light ...
Futaba Matsui, Sho T. Yamaguchi, Riho Kobayashi, Shiho Ito, Sakimi Nagashima, Zhiwen Zhou, Hiroaki Norimoto   +6 more
doaj   +1 more source

Suprachiasmatic VIP neurons are required for normal circadian rhythmicity and comprised of molecularly distinct subpopulations

Nature Communications, 2020
Cell groups in the hypothalamic suprachiasmatic clock contribute to the genesis of circadian rhythms. The authors identified two populations of vasoactive intestinal polypeptide-expressing neurons in the suprachiasmatic nucleus which regulate locomotor ...
William D. Todd, Anne Venner, Christelle Anaclet, Rebecca Y. Broadhurst, Roberto De Luca, Sathyajit S. Bandaru, Lindsay Issokson, Lauren M. Hablitz, Olga Cravetchi, Elda Arrigoni, John N. Campbell, Charles N. Allen, David P. Olson, Patrick M. Fuller   +13 more
doaj   +1 more source

The Suprachiasmatic Nucleus Regulates Anxiety-Like Behavior in Mice

Frontiers in Neuroscience, 2022
Individuals suffering from mood and anxiety disorders often show significant disturbances in sleep and circadian rhythms. Animal studies indicate that circadian rhythm disruption can cause increased depressive- and anxiety-like behavior, but the ...
Chelsea A. Vadnie, Kaitlyn A. Petersen, Lauren A. Eberhardt, Mariah A. Hildebrand, Allison J. Cerwensky, Hui Zhang, Jennifer N. Burns, Darius D. Becker-Krail, Lauren M. DePoy, Ryan W. Logan, Colleen A. McClung   +10 more
doaj   +1 more source

Rhythmic firing patterns in SCN: The role of circuit interactions [PDF]

, 1995
The suprachiasmatic nucleus (SCN) is believed to contain the main generator of circadian rhythmicity in mammals. In order to obtain further functional details of this, electrophysiological extracellular measurements in vitro were made.
Aguilar-Roblero, R., Barrio, R. A., Maini, P. K., Zhang, L.   +3 more
core   +2 more sources