Nerve growth factor, brain-derived neurotrophic factor, and the chronobiology of mood: a new insight into the "neurotrophic hypothesis" [PDF]
, 2015 The light information pathways and their relationship with the body rhythms have generated a new insight into the neurobiology and the neurobehavioral sciences, as well as into the clinical approaches to human diseases associated with disruption of ...
IANNITELLI, ANGELA +2 more
core +2 more sources
Global parameter search reveals design principles of the mammalian circadian clock [PDF]
, 2008 Background: Virtually all living organisms have evolved a circadian (~24 hour) clock that controls physiological and behavioural processes with exquisite precision throughout the day/night cycle.
AC Liu +46 more
core +5 more sources
Voluntary exercise can strengthen the circadian system in aged mice [PDF]
, 2013 Consistent daily rhythms are important to healthy aging according to studies linking disrupted circadian rhythms with negative health impacts. We studied the effects of age and exercise on baseline circadian rhythms and on the circadian system's ability ...
A Davidson +74 more
core +2 more sources
Acute knockdown of Kv4.1 regulates repetitive firing rates and clock gene expression in the suprachiasmatic nucleus and daily rhythms in locomotor behavior [PDF]
, 2017 Rapidly activating and inactivating A-type K+currents (IA) encoded by Kv4.2 and Kv4.3 pore-forming (α) subunits of the Kv4 subfamily are key regulators of neuronal excitability.
Granados-Fuentes, Daniel +4 more
core +2 more sources
The Melanocortin-4 Receptor Integrates Circadian Light Cues and Metabolism [PDF]
, 2015 The melanocortin system directs diverse physiological functions from coat color to body weight homoeostasis. A commonality among melanocortin-mediated processes is that many animals modulate similar processes on a circannual basis in response to longer ...
Arble, Deanna M. +10 more
core +2 more sources
Identification of the suprachiasmatic nucleus venous portal system in the mammalian brain
Nature Communications, 2021 The first known portal system in the mammalian brain was identified in 1933. Here the authors describe a new portal system between the capillary beds of the Suprachiasmatic Nucleus master clock and a circumventricular organ, enabling humoral signals to ...
Yifan Yao +3 more
doaj +1 more source
Stereotaxic Surgery for Suprachiasmatic Nucleus Lesions in Mice
Bio-Protocol, 2017 Site-specific lesions are invaluable methods for investigating the function of brain regions within the central nervous system and can be used to study neural mechanisms of behaviors. Precise stereotaxic surgery is required to lesion small regions of the
Kimiko Shimizu, Yoshitaka Fukada
doaj +1 more source
The Hypothalamus of the Beaked Whales: The Paraventricular, Supraoptic, and Suprachiasmatic Nuclei
Biology, 2023 The hypothalamus is the body’s control coordinating center. It is responsible for maintaining the body’s homeostasis by directly influencing the autonomic nervous system or managing hormones. Beaked whales are the longest divers among cetaceans and their
Simona Sacchini +3 more
doaj +1 more source
Circadian variation in gastric vagal afferent mechanosensitivity [PDF]
, 2013 Food intake is coordinated to cellular metabolism by clock gene expression with a master clock in the suprachiasmatic nucleus synchronized by light exposure.
Frisby, C.L. +4 more
core +2 more sources
Identification of sex hormone-binding globulin in the human hypothalamus [PDF]
, 2005 Gonadal steroids are known to influence hypothalamic functions through both genomic and non-genomic pathways. Sex hormone-binding globulin ( SHBG) may act by a non-genomic mechanism independent of classical steroid receptors.
Becchis M +35 more
core +1 more source