Results 31 to 40 of about 78 (77)

The Association Between Circadian Disruption in Core Body Temperature Rhythm and Post‐Chemotherapy Sleep Disturbances in Breast Cancer Survivors

Journal of Sleep Research, EarlyView.
ABSTRACT Sleep disturbance is a common symptom experienced by approximately 70% of breast cancer survivors and persists after the conclusion of chemotherapy. This study aimed to quantify the circadian disruption of the core body temperature (CBT) rhythm and its correlation with sleep disturbance following chemotherapy.
Joon Sung Shin, Sanghyup Jung, Geun Hui Won, Sun Hyung Lee, Jaehyun Kim, Saim Jung, Chan‐Woo Yeom, Kwang‐Min Lee, Kyung‐Lak Son, Jang‐il Kim, Sook Young Jeon, Han‐Byoel Lee, Bong‐Jin Hahm   +12 more
wiley   +1 more source

Dreaming of Better Treatments: Advances in Drug Development for Sleep Medicine and Chronotherapy

Journal of Sleep Research, EarlyView.
ABSTRACT Throughout history, the development of new sleep medicines has been driven by progress in our understanding of the mechanisms underlying sleep. Ancient civilisations used their understanding of the sedative nature of natural herbs and compounds to induce sleep.
Brooke A. Prakash, Ishani Shah, Guohao Ni, Sridhar Vasudevan, Aarti Jagannath, Russell G. Foster   +5 more
wiley   +1 more source

Long‐term sub‐erythemal UVB exposure does not impact circadian rhythms in mice under standard and rotating shift light conditions

Photochemistry and Photobiology, EarlyView.
Circadian disruption is a potential carcinogen, but the impact of environmental carcinogens on circadian rhythms is unclear. Here we evaluated the impact of chronic UVB exposure with environmental‐ and genetic‐induced circadian disruption on mouse rhythmic locomotor activity and clock gene expression. Created in BioRender. Cone, S.
Adam J. Greer, Sean J. Cone, Rachel Bernstein, Elizabeth Schuetz, Narayani Prasad Kar, Bala S. C. Koritala, Shobhan Gaddameedhi   +6 more
wiley   +1 more source

The causative role of amyloidosis in the cardiac complications of Alzheimer's disease: a comprehensive systematic review

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic illustration of the bidirectional causative link between cerebral amyloid‐beta (Aβ) angiopathy and cardiovascular disease in Alzheimer's disease (AD). Common cardiovascular risk factors like microvascular thrombosis, diabetes, atrial fibrillation, hypertension and atherosclerosis lead to cerebral hypoperfusion and ...
Samuel Parker, James Andrew, Mastitskaya Svetlana   +2 more
wiley   +1 more source

Multi‐Omic Analysis Reveals Astrocytic Annexin‐A2 as Critical for Network‐Level Circadian Timekeeping in the Suprachiasmatic Nucleus

Glia, Volume 73, Issue 7, Page 1483-1501, July 2025.
Main Points Multi‐omics reveal Annexin‐A2 (A2) and S100a10 (A10) as SCN astrocyte enriched proteins. Disrupting A2‐A10 complex elevates astrocyte Ca2+ and compromises SCN timekeeping. Astrocytic A2‐A10 is a critical control point for SCN network rhythms.
Andrew P. Patton, Toke P. Krogager, Elizabeth S. Maywood, Nicola J. Smyllie, Emma L. Morris, Mark Skehel, Michael H. Hastings   +6 more
wiley   +1 more source

Identification and Validation of Circadian Rhythm‐Related Genes Involved in Intervertebral Disc Degeneration and Analysis of Immune Cell Infiltration via Machine Learning

JOR SPINE, Volume 8, Issue 2, June 2025.
Within this manuscript, bioinformatics and experimental methods are used to explore the role of circadian rhythm and immunity in Intervertebral Disc Degeneration (IVDD). CCND1, FOXO1, FRMD8, NTRK2, PRRT1, and TFPI were successfully demonstrated to be hub rhythm‐related genes in the process of IVDD together with immunity.
Yongbo Zhang, Liuyang Chen, Sheng Yang, Rui Dai, Hua Sun, Liang Zhang   +5 more
wiley   +1 more source

Symptomatic narcolepsy in a dog with functional pituitary gland macroadenoma

Veterinary Record Case Reports, Volume 13, Issue 2, June 2025.
Abstract Symptomatic narcolepsy in dogs has been rarely reported. A 7‐year‐old, female, neutered Greek harehound presented with chronic progressive lethargy, dysphonia, episodes of flaccid paralysis of all limbs following excitement or eating, as well as pinnae and tail alopecia, hyperpigmentation and ‘rat tail’.
Christina Koufaki, Anastasia Karafylia, Ioannis Panopoulos, Dimitra Psalla, Nektarios Soubasis   +4 more
wiley   +1 more source

Meal timing, nutritional status and diet quality in a group of Spanish children

Pediatric Obesity, Volume 20, Issue 6, June 2025.
Summary Introduction Some studies suggest that meal timing is involved in obesity and metabolic health. However, little is known about children, so the aim was to assess whether meal timing patterns affect nutritional status and diet quality in children. Methods A cross‐sectional study was conducted on 880 children (8–13 years).
María Dolores Salas‐González, Viviana Loria‐Kohen, Aránzazu Aparicio, Laura M. Bermejo, Esther Cuadrado‐Soto, Liliana Guadalupe González‐Rodríguez, María del Carmen Lozano‐Estevan, África Peral‐Suárez, Adrián Cervera‐Muñoz, Rosa M. Ortega, Ana M. López‐Sobaler   +10 more
wiley   +1 more source

Suprachiasmatic nucleus [PDF]

Current Biology, 2002
openaire   +2 more sources

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Suprachiasmatic nucleus organization

Cell and Tissue Research, 2002
The suprachiasmatic nucleus (SCN) of the hypothalamus is a dominant circadian pacemaker in the mammalian brain controlling the rest-activity cycle and a series of physiological and endocrine functions to provide a foundation for the successful elaboration of adaptive sleep and waking behavior. The SCN is anatomically and functionally organized into two
Robert Y. Moore, Rehana K. Leak, Joan C. Speh   +2 more
openaire   +2 more sources