Results 51 to 60 of about 78 (77)
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Synaptology of the rat suprachiasmatic nucleus
Cell and Tissue Research, 1976Within the suprachiasmatic nucleus (SCN) of the rat the fine structure of the synapses and some features of their topological arrangement were studied. Five types of synapses could be distinguished with certainty: A. Two types of Gray-type-I (GTI) or asymmetrical synapses (approximately 33%).
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Mechanism of bilateral communication in the suprachiasmatic nucleus
European Journal of Neuroscience, 2013AbstractThe central circadian pacemaker of the suprachiasmatic nuclei (SCN) is a bilaterally symmetrical structure. Little is known about the physiological mechanisms underlying communication between the left and right SCN and yet the degree of synchronization between SCN neurons can have a critical impact on the properties of the circadian system.
Christopher S. Colwell +7 more
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Resetting the suprachiasmatic nucleus clock
Frontiers in Bioscience, 2004Recent research on the cellular basis of circadian rhythmicity has stressed the importance of clock genes for the maintenance of normal rhythmicity. There have been tremendous advances in our understanding of the inter-relationships of the various genes known to generate the rhythms.
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Melatonin receptors in the mammalian suprachiasmatic nucleus
Behavioural Brain Research, 1995The SCN of the hypothalamus, the site of the circadian pacemaker in mammals, is endowed with melatonin receptors of the ML-1 subtype. Here, we present evidence suggesting that activation of melatonin receptors in the SCN regulates circadian rhythms of behavior in the mouse. In a paradigm simulating a eastbound transmeridian flight, timed administration
Monica I. Masana +2 more
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Efferent connections of the rat suprachiasmatic nucleus
Neuroscience, 1981Abstract The efferent projections of the suprachiasmatic nucleus were studied in rats using three different light-microscopic tracing techniques. These techniques included, (1) degeneration subsequent to lesions of the nucleus, (2) autoradiography of axoplasmically-transported molecules following injections of [ 3 H]leucine into the nucleus ...
R.L. Moss +2 more
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Serotonin innervation of the primate suprachiasmatic nucleus
Brain Research, 2004The suprachiasmatic nucleus (SCN) in rodents receives a dense innervation from serotonin neurons of the midbrain raphe. This projection overlaps the terminal field of the retinohypothalamic tract in the SCN core, the central part of the nucleus characterized by a population of vasoactive intestinal polypeptide (VIP)-containing neurons.
Robert Y. Moore, Joan C. Speh
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Immunocytochemistry on Suprachiasmatic Nucleus Slices
2007Immunocytochemistry (ICC) is a sensitive and powerful method that is used to localize and identify cells containing a particular antigen. This chapter is dedicated to ICC of suprachiasmatic nucleus (SCN) slices. After a brief introduction to the technique, the materials and methods sections describe two different methods to obtain SCN slices--the first
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Non‐photic signalling in the suprachiasmatic nucleus
Biology of the Cell, 1997Scheduled arousal by handling and sub‐cutaneous saline injection entrains the free‐running clock of the adult Syrian hamster and outbred (ID(ICR)) but not inbred (C57B16) mice. Syrian hamsters bearing lesions of the intergeniculate leaflet of the thalamus remain able to entrain and phase‐shift to light, but the lesions block completely entrainment by ...
Francis J. P. Ebling +5 more
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Cellular Interactions in the Suprachiasmatic Nucleus. [PDF]
, 1997 Abstract : We studied neurochemical mechanisms related to control of the activity of these cells. Modulation of the neuronal activity here plays animportant role in determining the phase of the circadian cycle. We examined neuromodulation of GABA and glutamate actions in cells of the SCN. Neuromodulation is based on the concept that neuromodulators can
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Paradoxical effects of NPY in the suprachiasmatic nucleus
European Journal of Neuroscience, 2006AbstractThe circadian clock in the suprachiasmatic nucleus (SCN) is synchronized by the 24 h, light : dark cycle, and is reset by photic and non‐photic cues. The acute effects of light in the SCN include the increase of mRNA levels of the circadian clock gene Per1 and a dramatic reduction of pineal melatonin.
H. Elliott Albers +4 more
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