Results 61 to 70 of about 206,828 (247)

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

CA 125 dan Pemakaian Klinis Dalam Penatalaksanaan Kanker Ovarium

open access: yesQanun Medika: Jurnal Kedokteran Fakultas Kedokteran Universitas Muhammadiyah Surabaya, 2018
Today there are three types of ovarian cancer, namely epithelial cell tumors (70%), which are the largest part of the tumor, Germ cell tumors with a smaller frequency, and sex cord-stroma tumors which is the smallest proportion of about 8% of neoplasm ...
Ninuk Dwi ariningtyas
doaj   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Differential Expression of Claudin Family Proteins in Mouse Ovarian Serous Papillary Epithelial Adenoma in Aging FSH Receptor-Deficient Mutants

open access: yesNeoplasia: An International Journal for Oncology Research, 2006
Ovarian cancer is a deadly disease with long latency. To understand the consequences of loss of folliclestimulating hormone receptor (FSH-R) signaling and to explore why the atrophic and anovulatory ovaries of follitropin receptor knockout (FORKO) mice ...
Jayaprakash Aravindakshan   +2 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

open access: yesFEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki   +5 more
wiley   +1 more source

Diagnostic Accuracy of Intraoperative Frozen Section and Causes of Error in Ovarian Epithelial Tumors: An Institutional Experience

open access: yesMiddle East Journal of Cancer, 2017
Background: Ovarian cancer is the second most common type of female genital tract malignancy. Treatment planning differs for benign, borderline, and malignant subtypes of surface epithelial tumors and depends on accurate histopathological diagnosis ...
Fatemeh Nili   +2 more
doaj  

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

ID8 cells manifest phenotypic plasticity and molecular heterogeneity of high-grade serous ovarian cancer in response to the local tissue niche

open access: yesScientific Reports
Spontaneously transformed mouse ovarian surface epithelial cell line ID8 generates a syngeneic mouse model, recapitulating the primary and metastatic stages of the malignancy hence, frequently used in pre-clinical evaluation.
Ritika Gupta   +4 more
doaj   +1 more source

A study of ovarian tumors at Kathmandu medical college teaching hospital

open access: yesJournal of Pathology of Nepal, 2017
Background: Ovarian cysts, which present as neoplastic and non-neoplastic lesions, are the most common gynecological cause of hospital admissions. This study was conducted to know the spectrum of ovarian tumors.Materials and methods: A cross sectional ...
Sailesh Bahadur Pradhan   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy