Results 241 to 250 of about 578,287 (295)

Dispersion Inhibits Thermal Mitigation of Pseudomonas aeruginosa Biofilms on Self-Heating Surfaces. [PDF]

open access: yesMicrobiologyopen
Parnian P   +5 more
europepmc   +1 more source

Comparison of surface modification and solid dispersion techniques for drug dissolution

International Journal of Pharmaceutics, 2000
Surface modification and solid dispersion formulations using hydrophilic excipients can significantly alter the dissolution behaviour of hydrophobic drug materials. The effect of these techniques used individually and in combination on the dissolution properties of the hydrophobic drug, phenylbutazone (PB), are compared. PB was treated with a poloxamer,
C, Rouchotas, O E, Cassidy, G, Rowley
exaly   +3 more sources

A novel surface-attached carvedilol solid dispersion with enhanced solubility and dissolution

Archives of Pharmacal Research, 2013
A novel surface-attached, spray-dried solid dispersion containing poorly water-soluble carvedilol (CV) without any change in the crystallinity was prepared using water, polyvinylpyrrolidone (PVP K30) and Tween 80. The solid dispersion was optimized by investigating the effects of the weight ratios of Tween 80/PVP K30 and carrier/drug on the aqueous ...
Tuan Hiep Tran   +2 more
exaly   +5 more sources

Surface Solid Dispersion – A Review

International Journal of Pharmaceutical Sciences and Nanotechnology, 2013
Preparation of an effective formulation of poorly water-soluble drugs is a key challenge in pharmaceutical technology. Dissolution rate and solubility are the rate- limiting steps for increasing the bioavailability of poorly water‐soluble drugs.
Sadhna Khatry, Neha Sood, Sandeep Arora
openaire   +1 more source

Surface-attached Solid Dispersion

Journal of Pharmaceutical Investigation, 2010
ABSTRACT − A novel surface-attached solid dispersion is designed to improve the solubility and oral bioavailability ofpoorly water-soluble drugs without crystalline change. Accordingly, it draws increasing interest because of excellent stabilityand no pollution for accomplishing enhanced solubility and bioavailability, which have recently been ...
Young-Joon Park   +6 more
openaire   +1 more source

The effect of processing on the surface physical stability of amorphous solid dispersions

European Journal of Pharmaceutics and Biopharmaceutics, 2014
The focus of this study was to investigate the effect of processing on the surface crystallization of amorphous molecular dispersions and gain insight into the mechanisms underpinning this effect. The model systems, amorphous molecular dispersions of felodipine-EUDRAGIT® E PO, were processed both using spin coating (an ultra-fast solvent evaporation ...
Qi, Sheng   +5 more
openaire   +3 more sources

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