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Solid State Transitions and Cap Availability in Surface Solid Dispersions of Chloramphenicol Stearate Polymorphs

Drug Development and Industrial Pharmacy, 1988
AbstractBy grinding, chloramphenicol stearate Form III turns into Form I: then this form tends to become amorphous. So the grinding of both forms produces a “physically activated” form (FI*) with low crystallinity degree and high CAP availability.
FORNI, Flavio   +4 more
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Mesoscopic model for the surface fractal dimension estimation of solid-solid and gas-solid dispersed systems

Surfaces and Interfaces, 2020
Abstract The surface of dispersed systems in which the dispersion medium is solid presents a complex morphology that depends on the processes associated with the formation of the solid phase and the dispersion grade of the dispersed phase. Considering that this morphology is a manifestation of the stochastic processes in the disperse phase, a ...
Edgardo J. Suarez-Dominguez   +4 more
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Surface Tracking of Curcumin Amorphous Solid Dispersions Formulated by Binary Polymers

Journal of Pharmaceutical Sciences, 2020
Herein, curcumin amorphous solid dispersions (Cur ASDs) were prepared using binary polymers (Eudragit EPO with polyvinylpyrrolidone K30 [EuD-PVP], Eudragit EPO with hydroxypropyl methylcellulose E50 [EuD-HPMC]) as excipient, and surface tracking of Cur ASDs was mainly addressed.
Na, Fan, Tong, Lu, Jing, Li
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Exact surface-plasmon dispersion relation for spatially dispersive solid with an abrupt surface

Vacuum, 1997
Abstract The exact surface-plasmon dispersion relation for a semi-infinite medium with an abrupt surface and an arbitrary wave-vector and frequency dependent dielectric function ϵ(q,ω) is obtained. The result is applied to the models with hydrodynamic and Lindhard dielectric functions and the comparison with other theories and the experiment is ...
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Surface composition and contact angle relationships for differently prepared solid dispersions

European Journal of Pharmaceutics and Biopharmaceutics, 2008
Solid dispersions are promising drug delivery forms which offer the possibility to disperse a hydrophobic drug in a hydrophilic matrix and thereby improve the dissolution behavior and the bioavailability of the drug. One important aspect and a prerequisite in understanding the drug dissolution mechanism from solid dispersions is a better analytical ...
Carina, Dahlberg   +2 more
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Development of Nifedipine Amorphous Solid Dispersion Composed of Surface-Active Agents

Key Engineering Materials, 2021
The amorphous solid dispersions (ASDs) containing amino methacrylate copolymer and surface-active agents were prepared to improve the nifedipine (NDP) dissolution. The different types of surface-active agent i.e., polysorbates 80, sodium lauryl sulfate (SLS) and polyethylene glycol (PEG) 400 were used. In order to evaluate the ASDs formulation,powder X-
Sukannika Tubtimsri, Yotsanan Weerapol
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Enhancement of the Ionic Conductivity in Solid‐Solid‐Dispersions by Surface Induced Defects

Berichte der Bunsengesellschaft für physikalische Chemie, 1984
AbstractThe finding that dispersions of insulators such as alumina or silica in ionic conductors may exhibit considerably enhanced ionic conductivities compared to the pure material, has become a promising topic for optimizing the electric properties in solid state research.
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Alternative Solvent-Free Preparation Methods for Felodipine Surface Solid Dispersions

Drug Development and Industrial Pharmacy, 1998
Surface solid dispersions were prepared via physical mixture and were either heated in a vacuum dryer or in a microwave oven for different periods of time. The physical state of felodipine in solid dispersions was studied using differential scanning calorimetry and x-ray powder diffractometry.
J, Kerc, S, Srcic, B, Kofler
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Photonic Control of Surface Anchoring on Solid Colloids Dispersed in Liquid Crystals

Langmuir, 2011
The anchoring of liquid-crystal (LC) mesogens to the surfaces of colloids is an important factor in determining intercolloidal interactions and the symmetry of the ensuing colloidal assembly in nematic colloids. The dynamic control of surface anchoring could therefore provide a handle to tune the colloidal organization and resulting properties in these
Chandran, S. Prathap   +4 more
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Dispersion-Polar Surface Tension Properties of Organic Solids

The Journal of Adhesion, 1970
ABSTRACT A new definition for work of adhesion Wa is applied to computationally define the dispersion γs d and polar γs d components of the solid surface tension γs = γs d + γs d for twenty-five low energy substrates. These calculated surface properties are correlated with surface composition and structure.
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