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Mesoscopic model for the surface fractal dimension estimation of solid-solid and gas-solid dispersed systems

Surfaces and Interfaces, 2020
Abstract The surface of dispersed systems in which the dispersion medium is solid presents a complex morphology that depends on the processes associated with the formation of the solid phase and the dispersion grade of the dispersed phase. Considering that this morphology is a manifestation of the stochastic processes in the disperse phase, a ...
Edgardo J. Suarez-Dominguez   +4 more
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Development of Nifedipine Amorphous Solid Dispersion Composed of Surface-Active Agents

Key Engineering Materials, 2021
The amorphous solid dispersions (ASDs) containing amino methacrylate copolymer and surface-active agents were prepared to improve the nifedipine (NDP) dissolution. The different types of surface-active agent i.e., polysorbates 80, sodium lauryl sulfate (SLS) and polyethylene glycol (PEG) 400 were used. In order to evaluate the ASDs formulation,powder X-
Sukannika Tubtimsri, Yotsanan Weerapol
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Surface composition and contact angle relationships for differently prepared solid dispersions

European Journal of Pharmaceutics and Biopharmaceutics, 2008
Solid dispersions are promising drug delivery forms which offer the possibility to disperse a hydrophobic drug in a hydrophilic matrix and thereby improve the dissolution behavior and the bioavailability of the drug. One important aspect and a prerequisite in understanding the drug dissolution mechanism from solid dispersions is a better analytical ...
Carina, Dahlberg   +2 more
openaire   +2 more sources

Surface Solid Dispersion of Ketoconazole on Trehalose Dihydrate using Spray Drying to Achieve Enhanced Dissolution Rate

AAPS PharmSciTech
Ketoconazole (K) is a poorly water-soluble drug that faces significant challenges in achieving therapeutic efficacy. This study aimed to enhance the dissolution rate of ketoconazole by depositing spray-dried ketoconazole (SK) onto the surface of ground ...
Wanlop Weecharangsan, Robert J. Lee
semanticscholar   +1 more source

Soluplus® based solid dispersion as fast disintegrating tablets: a combined experimental approach for enhancing the dissolution and antiulcer efficacy of famotidine

Drug Development and Industrial Pharmacy, 2020
Famotidine (FM) is considered among the first-line therapy for treatment of gastric ulcers; however, its poor aqueous solubility resulted in low bioavailability and limited therapeutic efficacy.
M. Basha, A. Salama, S. H. Noshi
semanticscholar   +1 more source

Exact surface-plasmon dispersion relation for spatially dispersive solid with an abrupt surface

Vacuum, 1997
Abstract The exact surface-plasmon dispersion relation for a semi-infinite medium with an abrupt surface and an arbitrary wave-vector and frequency dependent dielectric function ϵ(q,ω) is obtained. The result is applied to the models with hydrodynamic and Lindhard dielectric functions and the comparison with other theories and the experiment is ...
openaire   +1 more source

Dispersion-Polar Surface Tension Properties of Organic Solids

The Journal of Adhesion, 1970
ABSTRACT A new definition for work of adhesion Wa is applied to computationally define the dispersion γs d and polar γs d components of the solid surface tension γs = γs d + γs d for twenty-five low energy substrates. These calculated surface properties are correlated with surface composition and structure.
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Surface Roughness Effects with Solid Lubricants Dispersed in Mineral Oils

A S L E Transactions, 1984
The lubricating effectiveness of solid-lubricant dispersions are investigated in both point and line contacts using surfaces with both random and directional roughness characteristics. Friction and wear data obtained at relatively low speeds and at room temperature, indicate that the existence of solid lubricants such as graphite, MoS2, and PTFE in a ...
C. Cusano, P. R. Goglia, H. E. Sliney
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Photonic Control of Surface Anchoring on Solid Colloids Dispersed in Liquid Crystals

Langmuir, 2011
The anchoring of liquid-crystal (LC) mesogens to the surfaces of colloids is an important factor in determining intercolloidal interactions and the symmetry of the ensuing colloidal assembly in nematic colloids. The dynamic control of surface anchoring could therefore provide a handle to tune the colloidal organization and resulting properties in these
Chandran, S. Prathap   +4 more
openaire   +2 more sources

Solid Fluctuations and Dispersion in Liquid-Solid Fluidized Beds With Low Surface Tension Media

ASME-JSME-KSME 2011 Joint Fluids Engineering Conference: Volume 1, Symposia – Parts A, B, C, and D, 2011
Fluctuations and dispersion of solid particles were investigated in a liquid-solid fluidized bed of which diameter was 0.102 m and 2.5 m in height. Effects of liquid velocity (0.005 ∼ 0.13 m/s), particle size (0.5 ∼ 3.0 × 10−3 m) and surface tension of continuous liquid media (56 ∼ 72 × 10−3 N/m) on the fluctuation frequency and dispersion coefficient ...
H. O. Lim, M. J. Seo, Y. Kang, K. W. Jun
openaire   +1 more source

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