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Enhancing Ketoprofen Solubility: A Strategic Approach Using Solid Dispersion and Response Surface Methodology

Current Radiopharmaceuticals
Background: In the pharmaceutical sciences, the solubility profile of therapeutic molecules is crucial for identifying and formulating drugs and evaluating their quality across the drug discovery pipeline based on factors like oral bioavailability, metabolic transformation, biodistribution kinetics, and potential toxicological implications.
Devika, Tripathi   +2 more
openaire   +2 more sources

Application of Shereshefsky's equation for the determination of solid surface dispersion energy

Journal of the Chemical Society D: Chemical Communications, 1971
A simple method for obtaining solid surface dispersion energies by measuring adsorption from solution and applying Shereshefsky's equation has been tested with experimental data from the literature on the adsorption of stearic acid from C6H6 solution on to mercury, iron, copper, and nickel giving results that compare favourably with those obtained by ...
openaire   +1 more source

Preparation of Rapidly Disintegrating Glipizide Tablets by Surface Solid Dispersion through Superdisintegrants

International Journal of Pharmaceutical Sciences and Nanotechnology, 1970
The objective of this investigation was to enhance the dissolution of glipizide using solid dispersions containing different superdisintegrants and to prepare rapidly disintegrating glipizide tablets with rapid absorption through the oral cavity by direct compression of the prepared solid dispersion.
openaire   +1 more source

Reflectance Spectroscopy as a Tool for Investigating Dispersed Solids and Their Surfaces

Catalysis Reviews, 1968
Abstract Reflectance spectroscopy is potentially one of the most powerful experimental techniques to gain information on the electronic structure of the components of heterogeneous dispersed systems and their external as well as internal surfaces, including adsorbed layers.
openaire   +1 more source

Circulating tumor DNA in advanced solid tumors: Clinical relevance and future directions

Ca-A Cancer Journal for Clinicians, 2021
Michael L Cheng   +2 more
exaly  

Current and future cancer staging after neoadjuvant treatment for solid tumors

Ca-A Cancer Journal for Clinicians, 2021
James D Brierley Mb, Frcp   +1 more
exaly  

Tailoring inorganic–polymer composites for the mass production of solid-state batteries

Nature Reviews Materials, 2021
Li-Zhen Fan, Hongcai He, Ce-Wen Nan
exaly  

Navigating CAR-T cells through the solid-tumour microenvironment

Nature Reviews Drug Discovery, 2021
Andrew J Hou   +2 more
exaly  

Solid-state NMR spectroscopy

Nature Reviews Methods Primers, 2021
Bernd Reif   +2 more
exaly  

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