In this study solid dispersions of carbamazepine in the hydrophilic Kollidon® VA64 polymer, adsorbed onto Neusilin® UFL2 adsorption carrier have been employed to improve carbamazepine dissolution rate.
Tanja Vojinović +6 more
doaj +1 more source
Glucosamine HCl-based solid dispersions to enhance the biopharmaceutical properties of acyclovir [PDF]
The objective of the work presented here was to assess the feasibility of using glucosamine HCl as a solid-dispersion (SD) carrier to enhance the biopharmaceutical properties of a BCS class III/IV drug, acyclovir (ACV). The solid-dispersions of acyclovir
Bhagat, Snehal B. +6 more
core +1 more source
3-D multiobservable probabilistic inversion for the compositional and thermal structure of the lithosphere and upper mantle: III. Thermochemical tomography in the Western-Central U.S. [PDF]
Acknowledgments We are indebted to F. Darbyshire and J. von Hunen for useful comments on earlier versions of this work. This manuscript benefited from thorough and constructive reviews by W. Levandowski and an anonymous reviewer.
Aoki K. +10 more
core +2 more sources
Surface Solid Dispersion Technique for Solubility Enhancement of Nifedipine
Introduction: Poor solubility is a common challenge in pharmaceuticals, hindering oral bioavailability. High throughput screening has led to an increase in poorly soluble drug candidates. Enhancing solubility and dissolution rates is crucial for drug development.
Ganesh S. Mhaske +7 more
openaire +1 more source
Studies of intermolecular interactions in solid dispersions using advanced surface chemical analysis [PDF]
The aim of this study is to utilise an advanced surface chemical analysis based on X-ray photoelectron spectroscopy (XPS) to determine and characterise drug/polymer interactions in solid dispersions manufactured via hot melt extrusion (HME).
Maniruzzaman, Mohammed +3 more
openaire +3 more sources
FORMULATION AND EVALUATION OF IBUPROFEN CONTROLLED RELEASE MATRIX TABLETS USING ITS SOLID DISPERSION
Objective: The aim of the present work was to prepare solid dispersion of ibuprofen with PEG 6000 to increase the aqueous solubility of the drug and to develop the solid dispersed ibuprofen into tablet formulation with the combination of a hydrophilic ...
S. Manna, Jyoshna Kollabathula
semanticscholar +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Production of nanoparticles, of powders and setup of components for power equipment [PDF]
The paper presents ways to produce magnetic nanoparticles to be incorporated into magneto-bioelectronic devices where chemical processing must control composition, microstructure, phase purity, particle morphology, and control size particle, thereby ...
Patroi E, Bordianu A, Samoilescu G
doaj +1 more source
Long surface wave instability in dense granular flows [PDF]
In this paper we present an experimental study of the long surface wave instability that can develop when a granular material flows down a rough inclined plane.
Forterre, Y., Pouliquen, O.
core +3 more sources
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source

