Prognostic performance of Krebs von den Lungen-6, surfactant protein A, surfactant protein D levels in the serum and bronchoalveolar lavage fluid in chronic fibrosing interstitial pneumonia: a retrospective study [PDF]
Background The serum markers Krebs von den Lungen-6 (KL-6), surfactant protein A (SP-A), and surfactant protein D (SP-D) have been used for the diagnosis, differential diagnosis, and prognosis prediction of interstitial pneumonia.
Kentaro Wakamatsu +16 more
doaj +2 more sources
Loss of Surfactant Protein A Alters Perinatal Lung Morphology and Susceptibility to Hyperoxia-Induced Bronchopulmonary Dysplasia [PDF]
Bronchopulmonary dysplasia (BPD) is a condition of poor alveolar formation that causes chronic breathing impairment in infants born prematurely. Preterm lungs lack surfactant and are vulnerable to oxidative injuries driving the development of BPD.
Shaili Amatya +3 more
doaj +2 more sources
Surfactant proteins A and D: role in the pathogenesis of community-acquired pneumonia and possible predictive perspectives [PDF]
Community-acquired pneumonia is one of the most common infectious diseases and remains one of the leading causes of death in this group of diseases. Studies of community-acquired pneumonia are extremely relevant for modern clinical practice.
O. S. Kharlamovа +3 more
doaj +1 more source
Surfactant proteins SP-A and SP-D, which belong to the family of collagen-containing type C lectins, are used as diagnostic and prognostic markers for many acute and chronic respiratory diseases.
K. Yu. Nikolaev +4 more
doaj +1 more source
Biomarkers of Air-Blood Barrier Damage In COVID-19
The search for sensitive and specific markers enabling timely identification of patients with a life-threatening novel coronavirus infection (COVID-19) is important for a successful treatment.The aim of the study was to examine the association of ...
M. B. Khadzhieva +11 more
doaj +1 more source
Every year, about six million people die from tobacco use. Respiratory epithelium is the first line of defense against exogenous invasion, in particular, harmful inhaled particles, pathogens and allergens. However, the epithelium of the respiratory tract
O. S. Kharlamovа +3 more
doaj +1 more source
Association of SP-A and SP-D Surfactant Proteins with the Severity of CommunityAcquired Pneumonia
Relevance. In current clinical practice, there is a need for research to find new diagnostic tests for the purpose of determining the patients with the highest risk of death from pneumonia.
O. S. Kharlamova +3 more
doaj +1 more source
Clinical significance of the determination of surfactant proteins A and D in assessing the activity of lung sarcoidosis [PDF]
The results of a clinical study showing the importance of surfactant proteins A and D in assessing the activity and progression of idiopathic pulmonary fibrosis and chronic lung sarcoidosis are presented. Aim.
V D Beketov +9 more
doaj +1 more source
OBJECTIVE. To determine the contribution of surfactant system dysfunction (by level surfactant protein A (SP-A) of serum) to the formation of dyspnea in the subacute post-COVID (coronavirus disease) period in patients with COVID-19-associated pneumonia.
L.I. Konopkina, O.O. Shchudro
doaj +1 more source
The role of surfactant proteins SP-A and SP-D in viral infection: a focus on COVID-19
An immune response to invasion of viral pathogens is an integral part of maintaining the physiological functioning of the bronchopulmonary system and effective gas exchange.
O. S. Kharlamovа +2 more
doaj +1 more source

