Surfactant protein D modulates HIV infection of both T-cells and dendritic cells [PDF]
Surfactant Protein D (SP-D) is an oligomerized C-type lectin molecule with immunomodulatory properties and involvement in lung surfactant homeostasis in the respiratory tract.
Gaiha, Gaurav +28 more
core +1 more source
Surfactant function in neonates with respiratory distress syndrome [PDF]
The function of pulmonary surfactant of a group of 14 preterm neonates (birth weight 907 +/- 60 g) who suffered from severe respiratory distress syndrome (RDS) and who had received exogenous bovine lipid extracted surfactant on the first day of life was ...
Griese, Matthias +3 more
core +1 more source
Surfactant protein SP-B: one ring to rule the molecular and biophysical mechanisms of the pulmonary surfactant system. [PDF]
Pulmonary surfactant is a lipid/protein complex crucial to maintain mammalian lungs open, as it facilitates breathing mechanics through a dramatic reduction of surface tension at the air–liquid interface.
Alonso A, Olmeda B, Pérez-Gil J.
europepmc +2 more sources
Surfactant protein a in cystic fibrosis: supratrimeric structure and pulmonary outcome. [PDF]
The state of oligomerization of surfactant associated protein-A (SP-A) monomers differs between individuals. This likely affects SP-A's functional properties and could thereby influence clinical status in patients with lung diseases.
Karl Paul +23 more
core +1 more source
Analysis of lung surfactant phosphatidylcholine metabolism in transgenic mice using stable isotopes [PDF]
Stable isotope labelling of lipid precursors coupled with mass spectrometry-based lipidomic analyses and determination of isotope enrichment in substrate, intermediate and product pools provide the parameters needed to determine absolute flux rates ...
Grielof Koster +9 more
core +1 more source
Clinical biological and genetic heterogeneity of the inborn errors of pulmonary surfactant metabolism [PDF]
Pulmonary surfactant is a multimolecular complex located at the air-water interface within the alveolus to which a range of physical (surface-active properties) and immune functions has been assigned. This complex consists of a surface-active lipid layer
Griese, Matthias +5 more
core +1 more source
Pulmonary Surfactant and Drug Delivery: An Interface-Assisted Carrier to Deliver Surfactant Protein SP-D Into the Airways. [PDF]
This work is focused on the potential use of pulmonary surfactant to deliver full-length recombinant human surfactant protein SP-D (rhSP-D) using the respiratory air-liquid interface as a shuttle.
Cruz, Antonio +16 more
core +1 more source
Background The incidence of nontuberculous mycobacterial lung disease (NTM-LD) peaks in middle- and old age groups, coinciding with senescence; thus, chronic infectious diseases can accelerate frailty and worsen mental health in the elderly.
Kohei Fujita +8 more
doaj +1 more source
Latherin: a surfactant protein of horse sweat and saliva [PDF]
Horses are unusual in producing protein-rich sweat for thermoregulation, a major component of which is latherin, a highly surface-active, non-glycosylated protein.
Douglas L Bovell +33 more
core +2 more sources
A woman with a diagnosis of tuberous sclerosis complex (TSC) presented with TSC2 gene mutation and various manifestations, including epilepsy, renal angiomyolipomas (AML), and pathologically confirmed multifocal micronodular pneumocyte hyperplasia (MMPH).
Tetsuaki Shoji +7 more
doaj +1 more source

