Results 11 to 20 of about 41,070 (225)
Survivin 2α: a novel Survivin splice variant expressed in human malignancies [PDF]
Molecular Cancer, 2005 Background Survivin and its alternative splice forms are involved in critical cellular processes, including cell division and programmed cell death. Survivin is expressed in the majority of human cancers, but minimally in differentiated normal tissues ...
Honsey Laura E +2 more
doaj +5 more sources
Journal of Cell Science, 2019 Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death. Normally it is only expressed in actively proliferating cells, but is upregulated in most, if not all cancers;
Altieri, Dario C., Wheatley, Sally P.
core +5 more sources
Experimental dermatology, 2011 Survivin is a member of the inhibitor of apoptosis (IAP) protein family acting at the intersection between proliferation and cell survival. This protein exhibits low or undetectable expression in most adult tissues but is increased in the majority of ...
Muller, E.J. +5 more
core +4 more sources
Investigation of Survivin Promoter-31 G/C Polymorphism and Survivin Levels in Acromegaly
Endocrinology Research and Practice, 2021 Objevtive: Acromegaly is a rare disease characterized by growth hormone hypersecretion generally arising from pituitary adenomas. Survivin, an apoptosis inhibitor protein, plays an important role in cell cycle regulation and possibly involves hypophysis ...
Muzaffer İLHAN +7 more
doaj +2 more sources
Survivin and pancreatic cancer
World Journal of Clinical Oncology, 2011 Pancreatic cancer is estimated to be the fourth most common cancer in men and fifth in women in the world and has poor prognosis. In recent years, more and more effort has been put on the relationship between pancreatic cancer and apoptosis.
Bin-Bin Liu, Wang Wei-Hong, Liu Bin-Bin
core +3 more sources
Trace of survivin in cancer [PDF]
European Journal of Cancer Prevention, 2018 Survivin is one of the most cancer-specific proteins overexpressed in almost all malignancies, but is nearly undetectable in most normal tissues in adults. Functionally, as a member of the inhibitor of apoptosis family, survivin has been shown to inhibit
Yazdani-Nafchi, Farshad +4 more
core +4 more sources
Survivin in autoimmune diseases
Autoimmunity Reviews, 2017 Survivin is a protein functionally important for cell division, apoptosis, and possibly, for micro-RNA biogenesis. It is an established marker of malignant cell transformation.
Brisslert, Mikael, +10 more
core +3 more sources
Survivin and caspases serum protein levels and survivin variants mRNA expression in sepsis
Scientific Reports, 2021 Sepsis is a dysregulated host response to infection related to devastating outcomes. Recently, interest has been shifted towards apoptotic and antiapoptotic pathobiology.
Marianna Miliaraki +18 more
doaj +3 more sources
Concerted Action of Targeted Nucleic Acid Therapeutics as Flexible, Precision and Personalized Cancer Treatment. [PDF]
Adv Sci (Weinh)Combinations of small activating RNAs and small interfering RNAs were developed as personalized precision therapies that simultaneously activate tumor suppressors and silence oncogenes according to the molecular signatures of patient tumors. This combination strategy demonstrated superior anticancer efficacy, highlighting the promise of precision ...
Wu J +18 more
europepmc +2 more sources
SURVIVIN EXPRESSION IN ORAL SQUAMOUS CELL CARCINOMA [PDF]
Sanamed, 2023 Introduction: Survivin functions as an apoptosis inhibitor and a regulator of cell division. This study aimed to determine the correlation between survivin expression and clinicopathologic parameters of oral squamous cell carcinoma (OSCC) and determine ...
Antunovic Marija, Raonic Janja
doaj +1 more source