Results 271 to 280 of about 177,033 (306)

Sustainability by design for recombinant protein therapeutics

Drug Discovery Today
Recombinant protein therapeutics play a vital role in pharmacology, offering precise and effective treatments. However, their development faces sustainability challenges, including high attrition rates, resource-intensive processes, and complex supply chains, leading to waste, emissions, and high costs.
Renato Mastrangeli, Maria Concetta Audino, Steve Marquis Fernandes, Horst Bierau   +3 more
openaire   +2 more sources

Sustained Delivery of Proteins for Novel Therapeutic Products

Science, 1998
R ecent developments in biotechnology have resulted in a number of powerful new protein therapies for many heretofore untreatable conditions, including hepatitis C, multiple sclerosis, hormonal disorders, and different cancers.
R T, Bartus, M A, Tracy, D F, Emerich, S E, Zale   +3 more
openaire   +2 more sources

Mineralized cyclodextrin nanoparticles for sustained protein delivery

Carbohydrate Polymers, 2013
The extensive therapeutic potential of protein drugs has been severely limited by their instability and short biological half-lives in vivo. To prolong their therapeutic effects, a sustained delivery system is required. In this study, cyclodextrin-based polymeric nanoparticles (CD-NPs), mineralized by calcium phosphate as the diffusion barrier, were ...
Maharajan, Sivasubramanian, Thavasyappan, Thambi, Jae Hyung, Park   +2 more
openaire   +2 more sources

Environmentally Sustainable Fibers from Regenerated Protein

Biomacromolecules, 2008
Concerns for the environment and consumer demand are driving research into environmentally friendly fibers as replacements for part of the 38 million tonnes of synthetic fiber produced annually. While much current research focuses on cellulosic fibers, we highlight that protein fibers regenerated from waste or byproduct sources should also be ...
Andrew J, Poole, Jeffrey S, Church, Mickey G, Huson   +2 more
openaire   +2 more sources

Sustainable Alternatives to Conventional Proteins

Food Studies: An Interdisciplinary Journal
<p>Proteins are macronutrients that provide mechanical support and immune protection, generate movement, and control growth. Animal proteins are the most widely used protein source, containing all essential amino acids necessary for the human body.
Kübra Haktan, Pinar Ercan Karaayak
openaire   +1 more source

Polymers for the sustained release of proteins and other macromolecules

Nature, 1976
SINCE the first demonstration that silicone rubber1 could be used as an implantable carrier for sustained delivery of low molecular weight compounds in animal tissues, various drug delivery systems have been developed. But except for the reports of Davis2,3 and Girnbrone et al.4, there has been little success in the development of slow release agents ...
R, Langer, J, Folkman
openaire   +2 more sources

Perennial Grasses for Sustainable European Protein Production

2016
Compared with annual grain and seed crops, the production of perennial crops reduces losses of nutrients, the need for pesticides, and supports soil carbon build-up. This may help implementation of the EU Water Framework Directive (WFD); the Nitrates Directive; and support the new EU greenhouse gas reduction goals for agriculture.
Jørgensen, Uffe, Lærke, Poul Erik; id_orcid 0000-0002-2224-3893   +1 more
openaire   +2 more sources

Recombinant gelatin hydrogels for the sustained release of proteins

Journal of Controlled Release, 2007
A recombinant gelatin (HU4) containing part of the amino acid sequence of the alpha1-chain of human type I collagen was used for preparing hydrogels for the sustained release of proteins. HU4 gelatin was modified with methacrylate residues for chemical crosslinking and gel formation.
Sutter, M., Siepmann, J., Hennink, W.E., Jiskoot, W.   +3 more
openaire   +3 more sources

Plant Proteins for Sustainable and Healthy Meat Alternatives

Journal of Food Science
ABSTRACT The increasing environmental footprint of industrial livestock farming, including biodiversity loss, pollution, water depletion, and greenhouse gas emissions, has raised global concerns about the long‐term sustainability of conventional meat production.
Gaurvi Sood, Jasleen Kaur Bhasin, Piyush Kashyap, Rahul Mehra, Mohammad Idreesh Khan, Syed Amir Ashraf   +5 more
openaire   +2 more sources

Advancing sustainable biotechnology through protein engineering

Trends in Biochemical Sciences
The push for industrial sustainability benefits from the use of enzymes as a replacement for traditional chemistry. Biological catalysts, especially those that have been engineered for increased activity, stability, or novel function, and are often greener than alternative chemical approaches.
Amelia R. Bergeson, Hal S. Alper
openaire   +2 more sources