Results 101 to 110 of about 45,473 (153)

Cytotoxic effect of sensitized apleen lymphocytes with SV40 and SV40 induced tumor on SV40 transformed cells

open access: yesOkayama Igakkai Zasshi (Journal of Okayama Medical Association), 1973
Kuniyuki EGUSA, Keiko SATO, Takuzo ODA
openaire   +2 more sources

Prospects for an SV40 vaccine

Seminars in Cancer Biology, 2001
The identification of SV40 as a possible cause of human cancer leads to the question of whether the unique properties of the virus can be exploited to treat patients with SV40-positive mesotheliomas, which are otherwise refractory to successful intervention.
M J, Imperiale, H I, Pass, M G, Sanda
openaire   +4 more sources

Association of SV40 with human tumours

Seminars in Cancer Biology, 2001
SV40 was discovered as a contaminant of poliovirus vaccines that were inadvertently administered to millions of people in Europe and the United States between 1955 and 1963. Shortly afterwards, SV40 was proven to be oncogenic in rodents and capable of transforming human and animal cells in vitro.
Jasani B.   +10 more
openaire   +5 more sources

SV40-Mediated Immortalization

Experimental Cell Research, 1998
Human diploid cells have a limited life span, ending in replicative senescence, in contrast to cell lines derived from tumors, which show an indefinite life span and are immortal, suggesting that replicative senescence is a tumor suppression mechanism.
K K, Jha   +3 more
openaire   +2 more sources

SV40 and the pathogenesis of mesothelioma

Seminars in Cancer Biology, 2001
Malignant mesothelioma, a tumor of the pleura, pericardium, and peritoneum, is presently a worldwide problem. Current therapy is ineffective in slowing the course of the disease, and median survival from the time of diagnosis is rarely greater than 1 year.
P, Rizzo   +6 more
openaire   +2 more sources

Random integration of SV40 in SV40-transformed, immortalized human fibroblasts

Experimental Cell Research, 1987
We have studied the relationship between immortalization of SV40-transformed human embryonic fibroblasts and their SV40 integration sites. From several independently transformed cell pools, we have isolated clones which do not harbor unintegrated SV40 DNA. We have analysed whole-cell DNA from these clones, using the Southern blot method.
H, Hara, H, Kaji
openaire   +2 more sources

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2019
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  +8 more sources

Characterization of defective SV40 isolated from SV40-transformed cells

Virology, 1975
Abstract Defective SV40 viruses were isolated from SV40-transformed monkey, human and hamster cells after Sendai virus-mediated fusion of the transformed cells with TC7 cells, a stable line of African green monkey kidney cells. Viral isolates were concentrated and purified and the defective viruses examined by electron microscopy.
K, Huebner   +3 more
openaire   +2 more sources

Phosphorylation of SV40 large T antigen in SV40 nucleoprotein complexes

Virology, 1980
Abstract The SV40 large T antigen associated with SV40 nucleoprotein complexes containing SV40 (I) DNA is phosphorylated. Tryptic peptide analysis reveals two major phosphopeptides in nucleoprotein complex large T antigen similar to those found in unbound SV40 large T antigen, one peptide containing mainly phosphoserine and the other containing ...
K, Mann, T, Hunter
openaire   +2 more sources

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