Results 151 to 160 of about 216,233 (295)

Molecular Dynamics‐Guided Sterol Engineering of mRNA‐Lipid Nanoparticles Reprograms Biodistribution and Enhances Spleen‐Selective Immunity

Advanced Science, EarlyView.
Sterol engineering enables precise control of mRNA lipid nanoparticles by tuning membrane organization. Replacing cholesterol with bile acid‐derived sterols redirects protein expression from the liver to the spleen. Notably, CA‐20 LNP enhances antigen‐specific immune responses while exhibiting a favorable safety profile, highlighting sterols as a ...
Sanghyuk Jeon, Seo‐Hyeon Bae, Jungyong Ji, Jisun Lee, Hosam Choi, Min‐Ho Kang, Sang‐In Park, Hyemin Kim, Nakyung Lee, Hajin Lee, Seonghoon Kim, Jungmin Kim, Subin Yoon, Seonghyun Lee, Seongje Cho, Dahyeon Ha, Ayoung Oh, Sohee Jo, Huijeong Choi, Yeeun Lee, Sowon Lee, Hyo‐Jung Park, Gitak Nam, Jisu Shin, Yujin Kang, Wonpil Im, Kiyoun Lee, Jae‐Hwan Nam   +27 more
wiley   +1 more source

Ribosome dynamics during skeletal muscle repair and regeneration in mice and humans. [PDF]

Am J Physiol Cell Physiol
Cui M, Edman S, Jude B, Jannig PR, Horwath O, Shorter E, Koopmans PJ, Chambers TL, Jones RG, Nilsson A, Lanner JT, Sejersen T, Pontén E, Murach KA, Schilcher J, von Walden F.   +15 more
europepmc   +1 more source

Förord : Religiös förändring - kristenheten i Sverige efter millennieskiftet

, 2015
I detta förord presenteras temat för boken med motiveringen att de skett stora förändringar i det svenska religiösa landskapet och att det finns ett behov av att få en översikt över dessa förändringar särskilt avseende de kristna samfunden.
Liljefors Persson, Bodil,, Tidman, Nils-Åke   +1 more
core  

Probing Electrocatalyst Design for Product Selectivity in CO2 Reduction

Advanced Science, EarlyView.
Selective CO2 electroreduction is controlled by catalyst structure, dynamic surface reconstruction, adsorbate interactions, and reaction microenvironment. This review summarizes Cu‐ and non‐Cu‐based catalysts, single‐atom and molecular systems, degradation pathways, and operando/computational strategies for steering CO2RR toward hydrocarbons ...
Suvodeep Sen, Bapan Biswas, Apinya Ngoipala, Julia Wiktor, Ujjwal Pal, Shalini Singh   +5 more
wiley   +1 more source

Important Health Care Components to Promote Sexual and Reproductive Health Among Young Women With Attention-Deficit/Hyperactivity Disorder: A Delphi Study. [PDF]

Health Expect
Wallin K, Hanberger L, Wallin-Lundell I, Alehagen S, Hultsjö S.   +4 more
europepmc   +1 more source

Pasta, a Versatile Transcriptomic Clock, Maps the Chemical and Genetic Determinants of Aging and Rejuvenation

Advanced Science, EarlyView.
Pasta is a transcriptomic aging clock built on an age‐shift learning framework and trained on 17 000 samples across 21 datasets. It accurately predicts relative biological age across tissues, platforms, and species, captures stemness‐to‐senescence transitions, and identifies age‐modulatory perturbations.
Jérôme Salignon, Maria Tsiokou, Patricia Marqués, Enriqueta Rodríguez‐Diaz, Hazel Ang, Federico Pietrocola, Christian G. Riedel   +6 more
wiley   +1 more source

COVID-19 vaccination carries no association with childbirth rates in Sweden. [PDF]

Commun Med (Lond)
Nordvall D, Schön T, Hinkula J, Eriksson O, Spreco A, Dahlström Ö, Lyth J, Axelsson D, Gursky E, Blomberg M, Timpka T.   +10 more
europepmc   +1 more source

Mat, jord och frihet - en kampanj för småbönders rätt till försörjning [PDF]

, 2007
Andéer, Lina, FIAN Sverige
core  

Aberrant GRP78 Phase Transition Sustains Endothelial IRE1α Signaling and Drives Blood–Brain Barrier Failure in Cerebral Amyloid Angiopathy

Advanced Science, EarlyView.
Vascular Aβ40 corrupts GRP78 phase behavior in brain endothelial cells, sustaining IRE1α–TRAF2–JNK signaling and driving apoptosis, tight junction loss, and blood–brain barrier failure in cerebral amyloid angiopathy. Pharmacological IRE1α inhibition restores vascular integrity, reduces leakage, and improves functional outcomes, revealing a targetable ...
Honglin Zheng, Qiang Li, Haiyang Luo, Yapei Yuan, Na Zhang, Yongting Lu, Suying Duan, Jieshi Zhong, Hang Zhang, Chenyang Liu, Yaochong Zhang, Wenzhuo Zhao, Yaxuan Song, Tuo Wang, Si Yan, Yapeng Li, Han Liu, Yuan Gao, Zongping Xia, Yuming Xu   +19 more
wiley   +1 more source

Psychiatric disorders and intellectual disability impact epilepsy care in adolescents: A nationwide registry study. [PDF]

Epilepsia Open
Sobovitch J, Reilly C, Zelano J, Goselink RJM.   +3 more
europepmc   +1 more source