Results 101 to 110 of about 1,931 (193)

Growth and swainsonine production of Swainsona galegifolia (Andr.) R. Br. untransformed and transformed root cultures

, 1994
Untransformed and transformed root cultures of Swainsona galegifolla were established for swainsonine production. Transformed roots grew faster and produced higher swainsonine levels (62.3 μg g−1 DW) than untransformed roots (23.6 ,μg g−1 DW) or roots of
Ermayanti, T.M., O'Brien, P.A., McComb, J.A.   +2 more
core  

Swainsonine Inhibits Invasion and the EMT Process in Esophageal Carcinoma Cells by Targeting Twist1

, 2018
Esophageal cancer is a common gastrointestinal cancer, with a very high mortality rate in patients with metastasis. Swainsonine, a cytotoxic fungal alkaloid, has been shown to inhibit cell growth in esophageal cancer.
Junxun Ma, Haitao Tao, Lijie Wang, Danyang Sun, Jinyu Li, Yi Hu, Guoqing Zhang, Xiaoyan Li   +7 more
core   +1 more source

The potential importance of swainsonine in therapy for cancers and immunology

, 1991
Swainsonine, an indolizidine alkaloid, was initially used in biomedical research as a tool to investigate the biosynthesis and function of asparagine-linked \u27complex\u27 type oligosaccharide moieties of glycoproteins.
Oredipe, Oladipo A., Newton, Sheila A., Gause, Barry L., White, Sandra L., Yasuda, Yoshiaki, Olden, Kenneth, Breton, Pascal, Grzegorzewski, Krzysztof   +7 more
core  

Intoxicação por plantas que contêm swainsonina no Brasil Poisoning by swainsonine-containing plants in Brazil

Ciência Rural, 2013
No Brasil, as plantas que contêm swainsonina compõem um grupo muito importante de plantas tóxicas, incluindo Ipomoea carnea subsp. fistulosa, Ipomoea riedelii, Ipomoea sericophyla, Ipomoea verbascoidea, Turbina cordata e Sida carpinifolia, que causam ...
Carlos Alberto de Oliveira Júnior, Gabriela Riet-Correa, Franklin Riet-Correa   +2 more
doaj  

Augmentation of murine natural killer cell activity by swainsonine, a new antimetastatic immunomodulator

, 1988
Swainsonine, an indolizidine alkaloid, has been found to inhibit the experimental metastasis of B16-F10 melanoma cells when administered systemically to syngeneic C57BL/6 mice.
Olden, K, Matsumoto, K, White, S L, Molyneux, R J, Humphries, M J   +4 more
core   +1 more source

Swainsonine stimulates bone marrow cell proliferation and differentiation in different strains of inbred mice

, 2003
The immunomodulatory alkaloid swainsonine (8αβ-indolizidine-1α,2α,8β-triol) has potential for overcoming the bone marrow suppressive effects of cancer chemotherapeutic drugs and radiation.
Parish-Gause, Debra, Furbert-Harris, Paulette M., Oredipe, O. A., Griffin, Walter M., Vaughn, Theresa, Green, William R., Sridhar, Rajagopalan, Laniyan, Ibrahim, White, S. L., Olden, K.   +9 more
core  

Determination of alkaloid swainsonine in milkvetch using hydrophilic interaction chromatography-tandem mass spectrometry.

, 2016
Swainsonine, an indolizidine alkaloid, is found in some Astragalus, Oxytropis, and Swainsona species of the Leguminosae family growing throughout the world.
Butkutė, Emilija,
core  

Pharmacologic glycoengineering of Fcγ receptor IIIa enhances force-resistant IgG-FcγR interactions and anti-tumor antibody efficacy. [PDF]

Immunity
Cheng BY, Centeio RM, Chiu DK, Kiyohara CL, Herzog E, Dahan R, Thomas WE, Wang TT.   +7 more
europepmc   +1 more source

Seasonal Variation in Swainsonine and Endophyte Concentrations of Undifilum oxytropis in Different Plant Parts of Oxytropis sericea

, 2018
: Locoweeds (Astragalus and Oxytropis spp.) are widely distributed in the rangelands of the western United States. The primary toxin present in locoweeds is identified as the alkaloid swainsonine.
Shi, Lei
core  

<i>In silico</i> evaluation of soursop (<i>Annona muricata</i>) leaf compound interactions with CYP450 and their potential impact on systemic cancer therapies. [PDF]

Toxicol Rep
Ballesteros-Ramírez R, Fuenmayor D, Martínez-Ramos N, Duque-Grisales E, Murillo R.   +4 more
europepmc   +1 more source