Results 61 to 70 of about 63,331 (346)

Synergic Effects in the Activation of the Sweet Receptor GPCR Heterodimer for Various Sweeteners Predicted Using Molecular Metadynamics Simulations.

Journal of Agricultural and Food Chemistry, 2021
The sweet taste is elicited by activation of the TAS1R2/1R3 heterodimer G protein-coupled receptor. This is a therapeutic target for treatment of obesity and metabolic dysfunctions.
Jaewan Jang, Soo-Kyung Kim, Brian Guthrie, W. Goddard   +3 more
semanticscholar   +1 more source

Gut Bacteria Improve Depressive Symptoms by Degrading Cortisol into Androgen

Advanced Science, EarlyView.
Chronic stress is an important risk factor for stress‐related disorders such as depression. Stress hormone cortisol is essential for the pathogenesis of stress‐related disorders such as depression. Some gut microbiota degraded cortisol, and improve depressive symptoms.
Xiong Wang, Qing Wu, Hao‐Long Zeng, Yin Shen, Hong‐Han Zhang, Jun Gong, Qi Zhang, Jia‐Zhao Xie, Da‐Wei Ye, Zi‐Yong Sun, Zhong‐Chun Liu, Li‐Ming Cheng, Di Li   +12 more
wiley   +1 more source

Artificial Sweeteners Consumption among Alexandria University Students, Egypt

Journal of High Institute of Public Health, 2017
Background: The consumption of artificial sweeteners has increased in many countries worldwide. In the Arab world, there is little data about consumption pattern of artificial sweeteners especially among university students for their own eating ...
Nermine A Khamis, Olfat A Darwish
doaj   +1 more source

Nonnutritive sweeteners and cardiometabolic health: a systematic review and meta-analysis of randomized controlled trials and prospective cohort studies

Canadian Medical Association Journal, 2017
BACKGROUND Nonnutritive sweeteners, such as aspartame, sucralose and stevioside, are widely consumed, yet their long-term health impact is uncertain.
M. Azad, A. Abou-Setta, Bhupendrasinh F. Chauhan, R. Rabbani, Justin Lys, L. Copstein, A. Mann, Maya M Jeyaraman, Ashleigh Reid, Michelle Fiander, D. Mackay, J. McGavock, B. Wicklow, R. Zarychanski   +13 more
semanticscholar   +1 more source

Expert consensus on low-calorie sweeteners: facts, research gaps and suggested actions

Nutrition research reviews, 2020
A consensus workshop on low-calorie sweeteners (LCS) was held in November 2018 where seventeen experts (the panel) discussed three themes identified as key to the science and policy of LCS: (1) weight management and glucose control; (2) consumption ...
M. Ashwell, S. Gibson, F. Bellisle, J. Buttriss, A. Drewnowski, M. Fantino, A. Gallagher, K. de Graaf, S. Goscinny, C. Hardman, Hugo A Laviada-Molina, R. Lopez-garcia, B. Magnuson, D. Mellor, P. Rogers, I. Rowland, W. Russell, J. Sievenpiper, C. la Vecchia   +18 more
semanticscholar   +1 more source

ZNRD2 Mediated Nucleoprotein Aggregation Impairs Respiratory Syncytial Virus Replication

Advanced Science, EarlyView.
During RSV infection, nucleoprotein (N) forms RNA‐bound oligomers. The host protein ZNRD2 binds to these oligomers, promoting their transition into insoluble aggregates. These aggregates simultaneously sequester functional N to restrict viral production and disrupt chaperonin assembly quality control by interfering with ZNRD2's role as an adaptor ...
Haiwu Zhou, Mingbin He, Jinhong Du, Cong Liu, Weiwei Wang, Yuewen Han, Zhifei Li, Yali Qin, Mingzhou Chen   +8 more
wiley   +1 more source

Adding Sweeteners to Softwood Lumber: The WTO-NAFTA “Spaghetti Bowl” Is Cooking [PDF]

, 2006
With the Doha round in trouble, the so-called spaghetti bowl of multilateral trade rules and proliferating regional trade deals, is, once again, prominently on the radar screen of the international trade community.
Pauwelyn, Joost H. B.
core   +1 more source

Review of the nutritional benefits and risks related to intense sweeteners [PDF]

, 2015
peer reviewedBackground: The intense sweeteners currently authorised in Europe comprise ten compounds of various chemical natures. Their overall use has sharply risen in the last 20 years.
Catherine Atlan, Esther Kalonji, Fabienne Rajas, Gérard Slama, Irène Margaritis, Jacques Belegaud, Jean-Philippe Girardet, Marie-Chantal Canivenc-Lavier, Murielle Bortolotti, Olivier Bruyère, Perrine Nadaud, Sabine Houdart, Serge H. Ahmed, Sybil Charrière   +13 more
core   +5 more sources

Artificial Sweeteners Disrupt Tight Junctions and Barrier Function in the Intestinal Epithelium through Activation of the Sweet Taste Receptor, T1R3

Nutrients, 2020
The breakdown of the intestinal epithelial barrier and subsequent increase in intestinal permeability can lead to systemic inflammatory diseases and multiple-organ failure.
A. Shil, O. Olusanya, Zaynub Ghufoor, Benjamin Forson, J. Marks, H. Chichger   +5 more
semanticscholar   +1 more source

Edible Pneumatic Battery for Sustained and Repeated Robot Actuation

Advanced Science, EarlyView.
This work presents an edible energy source and valve system to power soft, pneumatically driven edible robots. A chemical reaction between sodium bicarbonate and citric acid generates carbon dioxide gas, and a pressure‐triggered edible valve enables self‐repetitive motion of the edible actuator.
Bokeon Kwak, Shuhang Zhang, Alexander Keller, Qiukai Qi, Jonathan Rossiter, Dario Floreano   +5 more
wiley   +1 more source