Genome-wide association study of the taste and hedonic ratings of the low-calorie sweetener acesulfame potassium. [PDF]
Kan M +5 more
europepmc +1 more source
This study underscores the significant influence of frailty and vitality on the subjective health experience of older cancer survivors with acceptance and control emerging as salient mediators. These findings affirm the conceptual and empirical robustness of the model highlighting its potential utility in shaping future interventions for older cancer ...
Damien S. E. Broekharst +4 more
wiley +1 more source
Causal association between artificial sweeteners and risk of 15 tumors: A 2-way 2-sample Mendelian randomization analysis. [PDF]
Yang H +8 more
europepmc +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Aspartame and cardiovascular disease: Unraveling potential molecular mechanisms through integrative network toxicology, molecular docking, and dynamics simulation. [PDF]
Yang T, Luo J, Zhang L, Li H, Wang J.
europepmc +1 more source
The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley +1 more source
The Potential Application of Prebiotic <i>Stevia rebaudiana</i> in Aquaculture and Animal Feed. [PDF]
Shehata AI +10 more
europepmc +1 more source
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
A cross-sectional analysis of the nutritional quality and prices of commercial infant and toddler food products in the Canadian food supply. [PDF]
Lee JJ +5 more
europepmc +1 more source

