Results 31 to 40 of about 3,579,556 (333)

Low-Voltage and High-Reliability RF MEMS Switch with Combined Electrothermal and Electrostatic Actuation

Micromachines, 2021
In this paper, we report a novel laterally actuated Radio Frequency (RF) Microelectromechanical Systems (MEMS) switch, which is based on a combination of electrothermal actuation and electrostatic latching hold.
Yong Zhu, Jitendra Pal
doaj   +1 more source

Switching and diffusion models for gene regulation networks [PDF]

, 2009
We analyze a hierarchy of three regimes for modeling gene regulation. The most complete model is a continuous time, discrete state space, Markov jump process.
Cao Y., Desmond J. Higham, Somkid Intep, Xuerong Mao   +3 more
core   +2 more sources

Exact solution of a model DNA-inversion genetic switch with orientational control

, 2008
DNA inversion is an important mechanism by which bacteria and bacteriophage switch reversibly between phenotypic states. In such switches, the orientation of a short DNA element is flipped by a site-specific recombinase enzyme.
D. W. Wolf, M. W. van der Woude, Martin R. Evans, Paolo Visco, Rosalind J. Allen   +4 more
core   +1 more source

Human lymphoma mutations reveal CARD11 as the switch between self-antigen-induced B cell death or proliferation and autoantibody production [PDF]

, 2016
Self-tolerance and immunity are actively acquired in parallel through a poorly understood ability of antigen receptors to switch between signaling death or proliferation of antigenbinding lymphocytes in different contexts.
Domaschenz, Heather, Fung, Herman, Goodnow, Christopher, Horikawa, Keisuke, Jeelall, Yogeshraj, Kallies, Axel, Law, Hsei-Di, Nutt, Stephen L, Wang, James   +8 more
core   +1 more source

Predicting Chronicity in Children and Adolescents With Newly Diagnosed Immune Thrombocytopenia at the Timepoint of Diagnosis Using Machine Learning‐Based Approaches

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives To identify predictors of chronic ITP (cITP) and to develop a model based on several machine learning (ML) methods to estimate the individual risk of chronicity at the timepoint of diagnosis. Methods We analyzed a longitudinal cohort of 944 children enrolled in the Intercontinental Cooperative immune thrombocytopenia (ITP) Study ...
Severin Kasser, Alice Bizeul, Meera Chitlur, Hugo Donato, Jelena Roganovic, Julia E. Vogt, Thomas Kühne   +6 more
wiley   +1 more source

Next-Gen Storage Infrastructure for ALICE [PDF]

EPJ Web of Conferences
ALICE introduced ground-breaking advances in data processing and storage requirements and presented the CERN IT data center with new challenges with the highest data recording requirement of all experiments.
Peters Andreas Joachim, Sindrilaru Elvin Alin, Betev Latchezar, Contescu Cristian, Del Monte Gianmaria, Ducret Vincent, Grigoras Costin, Lamanna Massimo, Mascetti Luca, Panzer-Steindel Bernd, Pomponi Daniele   +10 more
doaj   +1 more source

The Smallest Molecular Switch [PDF]

, 2003
Ab-initio total energy calculations reveal benzene-dithiolate (BDT) molecules on a gold surface, contacted by a monoatomic gold STM tip to have two classes of low energy conformations with differing symmetries.
Eldon G. Emberly, George Kirczenow, H. Sellers, M. Paulsson, M. H. Hettler, P. Damle, R. Landauer, R. Landauer, V. Mujica   +8 more
core   +1 more source

Intracellular Adenosine Triphosphate (ATP) Concentration: A Switch in the Decision Between Apoptosis and Necrosis

Journal of Experimental Medicine, 1997
Apoptosis and necrosis are considered conceptually and morphologically distinct forms of cell death. Here, we report that demise of human T cells caused by two classic apoptotic triggers (staurosporin and CD95 stimulation) changed from apoptosis to ...
M. Leist, B. Single, A. Castoldi, Simone Kühnle, P. Nicotera   +4 more
semanticscholar   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Switching Between LC-ESI-MS/MS and EMIT Methods for Routine TDM of Valproic Acid in Pediatric Patients With Epilepsy: What Clinicians and Researchers Need to Know

Frontiers in Pharmacology, 2021
Background: Valproic acid (VPA) is a widely used antiseizure medication and its dosing needs to be tailored individually through therapeutic drug monitoring (TDM) to avoid or prevent toxicity.
Ying Xia, Jia-Yi Long, Meng-Yuan Shen, Na Dong, Hong-Li Guo, Ya-Hui Hu, Xiao-Peng Lu, Xuan-Sheng Ding, Feng Chen, Jin-Chun Qiu   +9 more
doaj   +1 more source