Results 51 to 60 of about 3,579,556 (333)

Co-translational protein aggregation and ribosome stalling as a broad-spectrum antibacterial mechanism

open access: yesNature Communications
Drug-resistant bacteria pose an urgent global health threat, necessitating the development of antibacterial compounds with novel modes of action. Protein biosynthesis accounts for up to half of the energy expenditure of bacterial cells, and consequently ...
Laleh Khodaparast   +16 more
doaj   +1 more source

Design and Simulation of Fault Tolerant Algorithms in Network-on-Chip [PDF]

open access: yesمجله مدل سازی در مهندسی, 2008
  Nasibeh Siadaty,Karim Mohammadi     Iran University of Science & Technology - Department of Electrical engineering       Abstract   Increase of design complexity of assembled circuits, and on the other hand necessity to separation the activity ...
Nasibeh Siadaty, Karim Mohammadi
doaj   +1 more source

Switching Investments

open access: yesTheoretical Computer Science, 2010
We present a simple online two-way trading algorithm that exploits fluctuations in the unit price of an asset. Rather than analysing worst-case performance under some assumptions, we prove a novel, unconditional performance bound that is parameterised either by the actual dynamics of the price of the asset, or by a simplifying model thereof.
Koolen, W.M., de Rooij, S.
openaire   +3 more sources

The Off-Switch Game [PDF]

open access: yesInternational Joint Conference on Artificial Intelligence, 2016
It is clear that one of the primary tools we can use to mitigate the potential risk from a misbehaving AI system is the ability to turn the system off.
Dylan Hadfield-Menell   +3 more
semanticscholar   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

THz MEMS Switch Design

open access: yesMicromachines, 2022
In this work, an mm-wave/THz MEMS switch design process is presented. The challenges and solutions associated with the switch electrical design, modeling, fabrication, and test are explored and discussed.
Yukang Feng   +2 more
doaj   +1 more source

Selenium bond decreases ON resistance of light-activated switch [PDF]

open access: yes, 1965
Vitrified amorphous selenium bond decreases the ON resistance of a gallium arsenide-silicon light-activated, low-level switch. The switch is used under a pulse condition to prolong switch life and minimize errors due to heating, devitrification, and ...

core   +1 more source

Feature integration and task switching: diminished switch costs after controlling for stimulus, response, and cue repetitions [PDF]

open access: yes, 2016
This report presents data from two versions of the task switching procedure in which the separate influence of stimulus repetitions, response key repetitions, conceptual response repetitions, cue repetitions, task repetitions, and congruency are ...
Liefooghe, Baptist, Schmidt, James
core   +4 more sources

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Energetic profiling reveals thermodynamic principles underlying amyloid fibril maturation

open access: yesNature Communications
Amyloid fibrils adopt diverse structural polymorphs linked to disease-specific phenotypes, but the thermodynamic principles guiding their formation and maturation remain unclear.
Ramon Duran-Romaña   +3 more
doaj   +1 more source

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