Sympathetic Regulation of Hematopoiesis and the Mobilization of Inflammatory Cells in ICR Mice with Traumatic Brain Injury: A Novel Approach to Targeting Neuroinflammation and Degenerative Processes [PDF]
BiomedicinesBackground/Objectives: Neuroinflammation is a leading factor in secondary brain damage following a traumatic brain injury (TBI). Existing therapeutic approaches have limited efficacy against neuroinflammation.
Natalia Ermakova +6 more
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Sympathetic overactivity and nocturnal diuresis in obstructive sleep apnea alter the response to hypertension therapy [PDF]
Clinical HypertensionBackground Obstructive sleep apnea (OSA) is associated with high blood pressure that responds poorly to usual antihypertensive therapy. Methods and results Forty-one subjects with OSA had 25% higher plasma norepinephrine and 42% higher epinephrine ...
Michael G. Ziegler +3 more
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Dexmedetomidine for postoperative delirium in surgical patients: a mini-review of mechanisms, clinical evidence, and practical implementation [PDF]
Frontiers in PharmacologyPostoperative delirium (POD) is a common acute neurocognitive disorder in the perioperative period, significantly increasing the risks of mortality and long-term functional decline.
Xiao-yan Li +4 more
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Pediatric clonidine and guanfacine poisoning: a single-center retrospective review
Toxicology Communications, 2021 Clonidine and guanfacine are centrally acting sympatholytics (CAS). Poisoning with these agents is common in children, and management of this poisoning is controversial. We sought to characterize our experience with pediatric CAS poisonings.
Kevin Baumgartner, Michael Mullins
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Dexmedetomidine: present and future directions [PDF]
Korean Journal of Anesthesiology, 2019 Dexmedetomidine is a potent, highly selective α-2 adrenoceptor agonist, with sedative, analgesic, anxiolytic, sympatholytic, and opioid-sparing properties.
Seongheon Lee
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Minimal Side-effects and Adequate Analgesia in Spinal Anaesthesia: A Randomised Double Blinded Study Comparing Buprenorphine and Clonidine [PDF]
Journal of Clinical and Diagnostic Research, 2022 Introduction: Postoperative patient management includes managing the acute postoperative pain as well as the side-effects associated with the use of various medications in pain management.
DM Ramya, KN Vikas, Sudhir S Rao
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ARTERIAL HYPERTENSION IN YOUNG PEOPLE: EFFICACY OF SYMPATHOLYTIC THERAPY
Рациональная фармакотерапия в кардиологии, 2015 Aim. To evaluate the effect of imidasoline agonist, rilmenidine (Albarel), on 24-hour blood pressure (BP) profile and autonomic regulation of cardiovascular system in young patients with arterial hypertension (HT) and exogenous constitutional obesity ...
N. N. Nikitina +3 more
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Frontiers in Pharmacology, 2021 Human envenoming by Australian brown snakes (Pseudonaja spp.) may result in potentially life-threatening hypotension and subsequent cardiovascular collapse.
Nhi Thuc Vuong +2 more
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IHJ Cardiovascular Case Reports, 2019 Orthostatic hypertension (OHT) is a rarely described clinical entity. OHT is characterized by a significant and rapid increase in blood pressure when a person assumes an upright posture.
M.K. Bansal +3 more
doaj +1 more source
Place of imidazoline receptor agonists in the treatment of hypertension
Кардиоваскулярная терапия и профилактика, 2022 The review is devoted to selective I1-imidazoline-receptor agonists. An analysis of Russian and foreign studies is presented, the results of which indicate that this drug class not only provides adequate and long-term control of blood pressure, but also ...
D. V. Nebieridze, A. S. Safaryan
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