Role of Phospholipases A2 in Vascular Relaxation and Sympatholytic Effects of Five Australian Brown Snake, Pseudonaja spp., Venoms in Rat Isolated Tissues [PDF]
Frontiers in Pharmacology, 2021 Human envenoming by Australian brown snakes (Pseudonaja spp.) may result in potentially life-threatening hypotension and subsequent cardiovascular collapse.
Nhi Thuc Vuong +2 more
doaj +3 more sources
Sympatholytic Mechanisms for the Beneficial Cardiovascular Effects of SGLT2 Inhibitors: A Research Hypothesis for Dapagliflozin’s Effects in the Adrenal Gland [PDF]
International Journal of Molecular Sciences, 2021 Heart failure (HF) remains the leading cause of morbidity and death in the western world, and new therapeutic modalities are urgently needed to improve the lifespan and quality of life of HF patients.
Anastasios Lymperopoulos
exaly +3 more sources
Targeting Features of the Metabolic Syndrome Through Sympatholytic Effects of SGLT2 Inhibition [PDF]
Current Hypertension Reports, 2022 Purpose of Review The moderate glucose-lowering effect of sodium glucose co-transporter 2 (SGLT2) inhibitors is unlikely to explain SGLT2 inhibitor-mediated beneficial outcomes, and unravelling the underlying mechanisms is a high priority in the research
Lakshini Herat +2 more
exaly +3 more sources
Bromocriptine: A Sympatholytic, D2-Dopamine Agonist for the Treatment of Type 2 Diabetes [PDF]
Diabetes Care, 2011 Bromocriptine is a sympatholytic D2-dopamine agonist that has been approved for the treatment of type 2 diabetes. Based on animal and human studies, timed bromocriptine administration within 2 h of awakening is believed to augment low hypothalamic ...
R. DeFronzo
exaly +3 more sources
Direct Vasodilators and Sympatholytic Agents [PDF]
Journal of Cardiovascular Pharmacology and Therapeutics, 2015 Direct vasodilators and sympatholytic agents were some of the first antihypertensive medications discovered and utilized in the past century. However, side effect profiles and the advent of newer antihypertensive drug classes have reduced the use of these agents in recent decades.
Meghan N, McComb +2 more
semanticscholar +4 more sources
Central Sympatholytic Drugs [PDF]
Journal of Clinical Hypertension, 2011 Wanpen Vongpatanasin
exaly +4 more sources
Endovascular renal denervation: a novel sympatholytic with relevance to chronic kidney disease [PDF]
Clinical Kidney Journal, 2013 Endovascular renal denervation (sympathectomy) is a novel procedure developed for the treatment of resistant hypertension. Evidence suggests that it reduces both afferent and efferent sympathetic nerve activity, which may offer clinical benefit over and ...
N. Hoye +5 more
semanticscholar +2 more sources
ARTERIAL HYPERTENSION IN YOUNG PEOPLE: EFFICACY OF SYMPATHOLYTIC THERAPY
Рациональная фармакотерапия в кардиологии, 2015 Aim. To evaluate the effect of imidasoline agonist, rilmenidine (Albarel), on 24-hour blood pressure (BP) profile and autonomic regulation of cardiovascular system in young patients with arterial hypertension (HT) and exogenous constitutional obesity ...
N. N. Nikitina +3 more
doaj +6 more sources