Results 21 to 30 of about 3,566 (133)

Adrenal adrenoceptors in heart failure

Frontiers in Physiology, 2014
Heart failure (HF) is a chronic clinical syndrome characterized by the reduction in left ventricular (LV) function and it represents one of the most important causes of morbidity and mortality worldwide.
Claudio ede Lucia, Grazia Daniela eFemminella, Giuseppina eGambino, Gennaro ePagano, Elena eAllocca, Carlo eRengo, Carlo eRengo, Candida eSilvestri, Dario eLeosco, Nicola eFerrara, Nicola eFerrara, Giuseppe eRengo, Giuseppe eRengo   +12 more
doaj   +1 more source

ACUTE POLYUMERIA SYNDROME INDUCED BY DEXMEDETOMIDINE DURING SPINAL NEUROSURGERY (clinical observation)

Вестник анестезиологии и реаниматологии, 2018
Dexmedetomidine is a high-selective α2-agonist, which is used as an anesthetic component, and it is expected to induce polyuria. Initially, it was mainly used for sedation in emergency wards, and further this medicine got widespread use in anesthesiology.
A. V. Solenkova, O. N. Ivanova, A. M. Аrefiev, A. Yu. Lubnin, N. A. Konovalov, V. A. Korolishin, S. Yu. Timonin   +6 more
doaj   +1 more source

The place of modern α-2-agonists in the intraoperative sedation of trauma / orthopedic patients

Perioperative Medicine, 2020
Modern traumatological operations have a number of features: duration, a large pool of age-related patients with low functional reserves, forced position of the body, operations are often under regional anesthesia with a conserved consciousness, which ...
A Domoratskiy, V Kryliuk, I Kuchynska, T Pylypenko, A Pavlenko, D Horban   +5 more
doaj   +1 more source

Interventions to prevent postoperative neurocognitive complications: an umbrella review of meta‐analyses of randomised controlled trials

Anaesthesia, EarlyView.
Summary Introduction The certainty of the effectiveness of interventions to manage postoperative neurocognitive complications remains unclear. The objective of this umbrella review was to synthesise and evaluate the evidence for interventions aimed at reducing the incidence of peri‐operative neurocognitive complications.
Filippo D'Amico, Stefano Turi, Marco Manazza, Giuliana Lo Bianco, Giacomo Monti, Alberto Zangrillo, Giovanni Landoni, Luigi Beretta   +7 more
wiley   +1 more source

Acute Metabolic Effects of Thiopental Anesthesia on Fed and Fasted Rats Chronically Treated With Bromocriptine

Journal of Pharmacological Sciences, 2003
We investigated the acute effects of thiopental anesthesia (4 mg/100 g, i.v.) on plasma glucose, insulin, triacylglycerol, and prolactin levels in rats treated with bromocriptine (BR) (0.4 mg/100 g body wt, i.p., for two weeks).
Antônio Ribeiro de Oliveira, Jr., Leida Maria Botion, Rachel Menezes Guerra, Rodrigo Bastos Fóscolo, Lucas José Campos Machado, Umeko Marubayashi, Adelina Martha dos Reis, Câ;ndido Celso Coimbra   +7 more
doaj   +1 more source

Alpha‐2‐adrenoreceptor agonists as analgesic drugs in equine medicine

Equine Veterinary Education, EarlyView.
Summary Managing pain in horses is challenging despite the availability of nonsteroidal anti‐inflammatory drugs, local anaesthetics, opioids and α2‐adrenoreceptor agonists. While α2‐agonists are widely used for sedation and restraint, their analgesic properties remain underutilised.
J. A. E. Hubbell, J. Brandly, W. W. Muir III, J. Page, K. Hopster   +4 more
wiley   +1 more source

Increases in skin perfusion and blood oxygen in the non‐exercising human limbs during exercise in the heat: Implications for control of circulation

Experimental Physiology, EarlyView.
Abstract Blood flow in the inactive limb tissues and skin is widely thought to decline during incremental exercise to exhaustion due to augmented sympathoadrenal vasoconstrictor activity, but direct evidence to support this view is lacking. Here, we investigated the inactive‐forearm haemodynamic (Q̇forearm${\dot{Q}}_{\mathrm{forearm}}$) and oxygenation
Steven J. Trangmar, José González‐Alonso   +1 more
wiley   +1 more source

Effects of dexmedetomidine on cardiac electrical activity and ion currents: an experimental animal study

Türk Biyokimya Dergisi
Dexmedetomidine is a potent and highly selective alpha-2 adrenergic receptor agonist recognized for its sedative, hypnotic, analgesic, and sympatholytic properties.
Arun Funda, Ozturk Nihal, Erkan Orhan, Ozdemir Semir, Arun Oguzhan, Yanardag Sirma Basak, Ayaz Murat   +6 more
doaj   +1 more source

Noradrenergic regulation of skeletal muscle oxygen pressures: Impact of heart failure with preserved ejection fraction and heat therapy

Experimental Physiology, EarlyView.
Abstract Attenuation of sympathetic vasoconstriction during exercise (functional sympatholysis) contributes to skeletal muscle oxygen delivery–utilization matching. However, the extent to which muscle contractions impact noradrenergic regulation of interstitial oxygen pressures (PO2is${P_{{{\mathrm{O}}_2}}}_{{\mathrm{is}}}$; the driving force for blood–
Edward T. N. Calvo, Jacob M. Pontorno, Benjamin Zeidler, Taciane M. M. Pejon, Michael D. Belbis, Scott K. Ferguson, Craig J. Goergen, Timothy P. Gavin, Bruno T. Roseguini, Igor A. Fernandes, Daniel M. Hirai   +10 more
wiley   +1 more source

Renal denervation: time to open Pandora’s box

Swiss Medical Weekly, 2012
Depending on the populations studied and the definitions applied, the prevalence of treatment-resistant hypertension varies from 10% to 15%, but is higher in conditions associated with increased sympathetic drive, such as obesity, obstructive sleep
Yu-Mei Gu, Kei Asayama, Yan-Ping Liu, Jan A Staessen   +3 more
doaj   +1 more source