Results 31 to 40 of about 1,482 (172)

The Postural Tachycardia Syndrome (POTS): Pathophysiology, Diagnosis & Management [PDF]

open access: yes, 2006
Postural tachycardia syndrome (POTS), characterized by orthostatic tachycardia in the absence of orthostatic hypotension, has been the focus of increasing clinical interest over the last 15 years 1. Patients with POTS complain of symptoms of tachycardia,
Raj, Satish R
core   +1 more source

The Effects of Different Antihypertensives, Steroids, and Beta Blockers on COVID-19 Outcomes in a CKD and Non-CKD Cohort in Detroit, Michigan [PDF]

open access: yes, 2023
Initial studies during the COVID-19 pandemic reported angiotensin converting enzyme 2 inhibitors (ACE2i) could be associated with worse disease course due to potential increase in ACE2 receptors which SARS-CoV2 virus uses for cellular entry.
Ahmed, Maham   +14 more
core   +1 more source

Impact of early dexmedetomidine administration on short‐ and long‐term outcomes in critically traumatic brain injury patients: A retrospective study using the MIMIC‐IV database

open access: yesIbrain, EarlyView.
Our retrospective analysis of the Medical Information Mart for Intensive Care‐IV (MIMIC‐IV) database suggests that early use of dexmedetomidine is associated with lower short‐term (28‐day and in‐hospital) and long‐term (1‐year) mortality in patients with traumatic brain injury.
Yang Long   +6 more
wiley   +1 more source

Effect of diuretics on the plasma lipid profile [PDF]

open access: yes, 2017
Hypertension, dyslipidaemia, glucose intolerance (associated with insulin resistance and compensatory hyperinsulinaemia) and other abnormalities are complementary coronary risk factors which often occur in association.
de Courten, M.   +2 more
core  

Analgesic effects of alpha‐2‐adrenoreceptor agonists in equine medicine: systemic, spinal, and local applications

open access: yesEquine Veterinary Education, EarlyView.
Summary Alpha‐2‐adrenoreceptor agonists provide analgesia when used as sole agents but can also be used in combination with other drugs for their additive and potentially synergistic effects. Further, because of their effects on blood flow, alpha‐2‐adrenoreceptor agonists act to extend and perhaps intensify the effects of drugs, such as local ...
J. Brandly   +4 more
wiley   +1 more source

Increases in skin perfusion and blood oxygen in the non‐exercising human limbs during exercise in the heat: Implications for control of circulation

open access: yesExperimental Physiology, EarlyView.
Abstract Blood flow in the inactive limb tissues and skin is widely thought to decline during incremental exercise to exhaustion due to augmented sympathoadrenal vasoconstrictor activity, but direct evidence to support this view is lacking. Here, we investigated the inactive‐forearm haemodynamic (Q̇forearm${\dot{Q}}_{\mathrm{forearm}}$) and oxygenation
Steven J. Trangmar   +1 more
wiley   +1 more source

Noradrenergic regulation of skeletal muscle oxygen pressures: Impact of heart failure with preserved ejection fraction and heat therapy

open access: yesExperimental Physiology, EarlyView.
Abstract Attenuation of sympathetic vasoconstriction during exercise (functional sympatholysis) contributes to skeletal muscle oxygen delivery–utilization matching. However, the extent to which muscle contractions impact noradrenergic regulation of interstitial oxygen pressures (PO2is${P_{{{\mathrm{O}}_2}}}_{{\mathrm{is}}}$; the driving force for blood–
Edward T. N. Calvo   +10 more
wiley   +1 more source

Interventions to prevent postoperative neurocognitive complications: an umbrella review of meta‐analyses of randomised controlled trials

open access: yesAnaesthesia, Volume 81, Issue 4, Page 532-540, April 2026.
Summary Introduction The certainty of the effectiveness of interventions to manage postoperative neurocognitive complications remains unclear. The objective of this umbrella review was to synthesise and evaluate the evidence for interventions aimed at reducing the incidence of peri‐operative neurocognitive complications.
Filippo D'Amico   +7 more
wiley   +1 more source

Dexmedetomidine in cardiac surgery: Emphasis on interleukin-18 signaling pathway [PDF]

open access: yesJournal of Clinical and Basic Research
Background: Dexmedetomidine (Dex), a non-opioid anesthetic and highly selective alpha2 (α2) adrenergic receptor agonist, exerts beneficial effects by mitigating inflammation and myocardial injury during cardiac surgery.
Bassim Mohammed Jabbar Hatemi   +3 more
doaj  

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