Results 221 to 230 of about 372,410 (315)

Functional Disorder at the Neural Interface: How Disordered Nanostructures Promote Proper Growth and Differentiation in In Vitro Neural Cultures

Advanced Science, EarlyView.
This work provides a practical guide for neuroengineers to design advanced neural interfaces, embracing and tailoring the concept of functional disorder. By bridging 2D and 3D in vitro models, this work highlights how non‐periodic, spatially heterogeneous, multiscale nanotopography can enable more physiologically relevant platforms for studying neural ...
F. Maita, E. Palmieri, I. Lucarini, L. Montaina, L. Maiolo   +4 more
wiley   +1 more source

SynCAR platform for capturing neuronal synaptic proteopathic seeds. [PDF]

iScience
Sebastian RM, Kupp R, Nanavati D, Parfentev I, Krzystek TJ, Romanul N, Yanamandra K, Preiss CN, Manos JD, Wu HY, Volkova A, Crescenti S, Titterton K, Welker AM, Townsend M, Karran E, Langlois X, Wu JW.   +17 more
europepmc   +1 more source

Advances and Perspectives in Graphene‐Based Quantum Dots Enabled Neuromorphic Devices

Advanced Science, EarlyView.
Graphene‐based QDs are zero‐dimensional carbon nanomaterials with pronounced quantum confinement and tunable electronic structures. Herein, we summarize their synthesis strategies and functionalization methods, and highlight their functional roles and operating mechanisms in devices, as well as recent advances in neuromorphic electronics. We anticipate
Yulin Zhen, Wei Zeng, Zherui Zhao, JiYu Zhao, Ziyan Huang, Zhuo Chen, Kui Zhou, Guanglong Ding, Su‐Ting Han, Ye Zhou   +9 more
wiley   +1 more source

Fine‐Tuned Regulation of mRNA Translation and Transport by STAU2 Condensate Facilitates Neuronal Development and Plasticity

Advanced Science, EarlyView.
STAU2 undergoes phase separation to form dynamic condensates that package target mRNAs and deliver them to the distal ends of growing neuronal dendrites. STAU2 condensates stabilize embedded mRNAs and repress their translation. Synaptic activity bidirectionally remodels STAU2 condensates, coordinating local translation of STAU2‐associated mRNAs ...
Shijing Huang, Yuanyuan Chu, Ruiqian Zhao, Siyu Li, Yu Feng, Hongdan Zheng, Yunli Xie, Tong Wang, Wenyu Wen   +8 more
wiley   +1 more source

Partners in plasticity: serotonergic glial interactions in brain circuit remodeling. [PDF]

Front Neurosci
Miller VK, Broadie K.
europepmc   +1 more source

Remote Magnetomechanical Neuromodulation Uncovers Therapeutic Mechanisms for Alleviating Parkinsonian Symptoms in Freely Moving Mice

Advanced Science, EarlyView.
Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters, Lorenzo Signorelli, Christian Herff, Sophia Gimple, Renzo Riemens, Gunter Kenis, Kim Rijkers, Hamed Shabani, Jyh‐Jang Sun, Yasin Temel, Hans Clusmann, Danijela Gregurec, Sarah‐Anna Hescham   +12 more
wiley   +1 more source

Comparative Cochlear-Vestibular Aging Reveals Age-Aligned Mitochondrial Ultrastructural Burden, Mitophagy-Autophagy Remodeling, Synaptic Uncoupling, and Sensory Functional Decline. [PDF]

Aging Cell
Xie J, Zhang X, Tian J, Yan Y, Shi K, Pan Y, Zhang Y, Chen Z, Sun J, Lv H, Chen J, Ren X, Kamogashira T, Zhang X, Gao Y.   +14 more
europepmc   +1 more source

Retina‐Inspired Bi‐Based Terahertz Photonic Neuromorphic Devices

Advanced Science, EarlyView.
Combined with effective band alignment and substrate engineering, bismuth materials are introduced to form terahertz photonic bio‐inspired devices with picosecond short‐term plasticity to enable multi‐scene visual perception. Thus obtained hardware through the terahertz optical neural network (THz‐ONN) demonstrates high recognition accuracy, providing ...
Pujing Zhang, Donggang Xie, Longyu Shi, Mengyuan Wang, Huiwen Shi, Yu Wu, Menglei Li, Guangwei She, Peijie Wang, Wensheng Shi, Cunlin Zhang, Kuijuan Jin, Guozhen Yang, Qingli Zhou, Chen Ge   +14 more
wiley   +1 more source

Mapping cross-domain drivers of Alzheimer's disease risk through integrated network analysis. [PDF]

Alzheimers Dement
Cary GA, Keegan S, Wiley JC, Gockley J, Butler RR, Longo FM, Levey AI, Greenwood AK, Leal K, Carter GW, Emory‐Sage‐SGC‐JAX TREAT‐AD Center.   +10 more
europepmc   +1 more source