Results 251 to 260 of about 372,410 (315)

THEIMMUNOLOGICALSYNAPSE

open access: yesAnnual Review of Immunology, 2001
The adaptive immune response is initiated by the interaction of T cell antigen receptors with major histocompatibility complex molecule-peptide complexes in the nanometer scale gap between a T cell and an antigen-presenting cell, referred to as an immunological synapse.
Andrey Shaw, Mark Davis, Paul Allen
exaly   +4 more sources

The immunological synapse: a molecular machine controlling T cell activation.

Science, 1999
The specialized junction between a T lymphocyte and an antigen-presenting cell, the immunological synapse, consists of a central cluster of T cell receptors surrounded by a ring of adhesion molecules. Immunological synapse formation is now shown to be an
A. Grakoui   +6 more
semanticscholar   +1 more source

Stabilizing synapses

Science, 2021
Adenosine fine-tunes the fate of nascent synapses in brain ...
Blum, David, Lopes, Luísa
openaire   +3 more sources

Mitochondria at the Synapse

The Neuroscientist, 2006
Synapses are packed with mitochondria, complex organelles with roles in energy metabolism, cell signaling, and calcium homeostasis. However, the precise mechanisms by which mitochondria influence neurotrans mission remain undefined.
Cindy V, Ly, Patrik, Verstreken
openaire   +2 more sources

The immunological synapse

Molecular Immunology, 2002
The immunological synapse plays a central role in organising the immune system. Through their synaptic activity both T and B cells usually, but not always, acquire the information that critically determines the level and nature of the responses that they make. For T cells much of that information comes from epicrine and paracrine cell-cell interactions
R J, Creusot   +2 more
openaire   +2 more sources

The synapse in schizophrenia

European Journal of Neuroscience, 2014
AbstractIt has been several decades since synaptic dysfunction was first suggested to play a role in schizophrenia, but only in the last few years has convincing evidence been obtained as progress has been made in elucidating the genetic underpinnings of the disorder.
Andrew J, Pocklington   +2 more
openaire   +2 more sources

[Immunological synapses and neuronal synapses].

Medecine sciences : M/S, 2003
The interface between two cells from the immune system has recently been coined "immunological synapse". The authors review recent findings concerning the structure of the synapse formed between T lymphocytes and antigen-presenting cells. T cells can be part of different synapses, depending on the antigen-presenting cell (B cell hybridoma, proteo-lipid
Alain, Trautmann   +3 more
openaire   +1 more source

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