Results 91 to 100 of about 445,271 (401)

Why Neurons Have Thousands of Synapses, A Theory of Sequence Memory in Neocortex [PDF]

open access: yes, 2015
Neocortical neurons have thousands of excitatory synapses. It is a mystery how neurons integrate the input from so many synapses and what kind of large-scale network behavior this enables.
Ahmad, Subutai, Hawkins, Jeff
core   +3 more sources

Tunable Tactile Synapses Enabled by Erasable Doping in Iongel‐Gated Nanotube Network Transistors

open access: yesAdvanced Functional Materials, EarlyView.
Artificial tactile synaptic sensors are realized by an iongel‐gated single‐walled carbon nanotube (SWCNT) transistor with reversible doping characteristics. The device senses and memorizes tactile stimuli and exhibits gate bias‐dependent excitatory or inhibitory synaptic behavior.
Yan Huang   +5 more
wiley   +1 more source

Postsynaptic protein organization revealed by electron microscopy. [PDF]

open access: yes, 2019
Neuronal synapses are key devices for transmitting and processing information in the nervous system. Synaptic plasticity, generally regarded as the cellular basis of learning and memory, involves changes of subcellular structures that take place at the ...
Bi, Guo-Qiang   +4 more
core  

Multielement Filament Memristor Enabling Multifunctional Neuromorphic Device

open access: yesAdvanced Functional Materials, EarlyView.
A new type of memristor featuring a hybrid mechanism and multifunctional applications is introduced. The proposed single device combines the alloy metal filament with the oxygen vacancy filament to achieve both resistive and threshold switching with enhanced reliability, mimicking both biological synapses and nociceptors. This study shows that filament‐
Mingu Jang   +4 more
wiley   +1 more source

Ectopic localization of neural crest cells: etiological factor of scoliosis

open access: yesХирургия позвоночника, 2015
Objective. To identify cell phenotypes in vertebral body growth plates from patients with idiopathic scoliosis. Material and Methods. Cells were isolated from vertebral body growth plates both on convex and concave sides of the de- formity in 50 ...
Alla M. Zaidman   +6 more
doaj   +1 more source

Spiking Neural P Systems with Addition/Subtraction Computing on Synapses [PDF]

open access: yes, 2018
Spiking neural P systems (SN P systems, for short) are a class of distributed and parallel computing models inspired from biological spiking neurons.
Chen, Zhiqiang, Jiang, Yun
core  

Temperature‐Resilient Polymeric Memristors for Effective Deblurring in Static and Dynamic Imaging

open access: yesAdvanced Functional Materials, EarlyView.
A thermally stable organic memristor based on a thiadiazolobenzotriazole (TBZ) and 2,5‐Dioctyl‐3,6‐di(thiophen‐2‐yl)pyrrolo[3,4‐c]pyrrole‐1,4(2H,5H)‐dione (DPP)‐based conjugated polymer is presented, demonstrating reliable, gradual resistance switching across a wide temperature range (153–573 K).
Ziyu Lv   +15 more
wiley   +1 more source

cAMP-Inhibits Cytoplasmic Phospholipase A2 and Protects Neurons against Amyloid-β-Induced Synapse Damage

open access: yesBiology, 2015
A key event in Alzheimer’s disease (AD) is the production of amyloid-β (Aβ) peptides and the loss of synapses. In cultured neurons Aβ triggered synapse damage as measured by the loss of synaptic proteins. α-synuclein (αSN), aggregates of which accumulate
Clive Bate, Alun Williams
doaj   +1 more source

Protein synthesis at synaptic sites on dendrites [PDF]

open access: yes, 2001
Studies over the past 20 years have revealed that gene expression in neurons is carried out by a distributed network of translational machinery. One component of this network is localized in dendrites, where polyribosomes and associated membranous ...
Schuman, Erin M., Steward, Oswald
core   +1 more source

Strategies to Design and Optimize Artificial Antigen‐Presenting Cells for T Cell Expansion in Cancer Immunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
This review highlights recent advances in engineering artificial antigen‐presenting cells (aAPCs) as alternatives to dendritic cells for T cell expansion. Key design principles inspired by the immunological synapse are discussed, with emphasis on strategies for polyclonal and antigen‐specific T cell expansion.
Nguyen Thi Nguyen, Yu Seok Youn
wiley   +1 more source

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