Results 101 to 110 of about 471,836 (383)

Chimeric antigen receptor T cells form nonclassical and potent immune synapses driving rapid cytotoxicity

Proceedings of the National Academy of Sciences of the United States of America, 2018
Significance Davenport et al. discovered that the chimeric antigen receptor (CAR) immune synapse structure is different from the T cell receptor (TCR) synapse.
A. Davenport, Ryan S Cross, Ryan S Cross, K. Watson, Y. Liao, Wei Shi, H. Prince, P. Beavis, J. Trapani, M. Kershaw, David Ritchie, P. Darcy, P. Neeson, Misty R. Jenkins   +13 more
semanticscholar   +1 more source

Alkali Ion‐Incorporated HfO2 Dielectrics for Reconfigurable Neuromorphic Computing

Advanced Functional Materials, EarlyView.
This work presents an indium gallium zinc oxide (IGZO) transistor with an alkali cation‐integrated hafnium dioxide (HfO2) dielectric exhibiting synaptic behavior via ion retention. The solution‐based film fabrication strategy overcomes the limitations of atomic layer deposition (ALD) and precursor coating, enabling the control of synaptic retention ...
Seung Yeon Ki, In Cheol Kwak, Seonkwon Kim, Jihyun Kim, Dong Gue Roe, Se‐Jin Kim, Joohoon Kang, Jeong Ho Cho   +7 more
wiley   +1 more source

Chimera states in a multilayer network of coupled and uncoupled neurons

, 2017
We study the emergence of chimera states in a multilayer neuronal network, where one layer is composed of coupled and the other layer of uncoupled neurons.
Ghosh, Dibakar, Majhi, Soumen, Perc, Matjaz   +2 more
core   +1 more source

Astrocyte‐Guided Maturation of Neural Constructs in a Modular Biosynthetic Hydrogel for Biohybrid Neurotechnologies

Advanced Functional Materials, EarlyView.
A modular biosynthetic PVA–gelatin hydrogel crosslinked via visible‐light thiol‐ene chemistry is engineered as a coating for neural electrodes. Optimizing matrix composition and mechanical properties enables the hydrogel to support astrocytic populations that guide neural differentiation and functional maturation.
Martina Genta, Sofia Peressotti, Roberto Portillo‐Lara, Josef Goding, Rylie Green   +4 more
wiley   +1 more source

Optimal Self-Induced Stochastic Resonance in Multiplex Neural Networks: Electrical vs. Chemical Synapses

Frontiers in Computational Neuroscience, 2020
Electrical and chemical synapses shape the dynamics of neural networks, and their functional roles in information processing have been a longstanding question in neurobiology.
Marius E. Yamakou, Marius E. Yamakou, Poul G. Hjorth, Erik A. Martens, Erik A. Martens, Erik A. Martens   +5 more
doaj   +1 more source

TraNNsformer: Neural network transformation for memristive crossbar based neuromorphic system design

, 2017
Implementation of Neuromorphic Systems using post Complementary Metal-Oxide-Semiconductor (CMOS) technology based Memristive Crossbar Array (MCA) has emerged as a promising solution to enable low-power acceleration of neural networks. However, the recent
Ankit, Aayush, Roy, Kaushik, Sengupta, Abhronil   +2 more
core   +1 more source

Enhancing Synaptic Plasticity and Multistate Retention of Organic Neuromorphic Devices Using Anion‐Excessive Gel Electrolyte

Advanced Functional Materials, EarlyView.
Anion‐excessive gel‐based organic synaptic transistors (AEG‐OSTs) that can maintain electrical neutrality are developed to enhance synaptic plasticity and multistate retention. Key improvement is attributed to the maintenance of electrical neutrality in the electrolyte even after electrochemical doping, which reduces the Coulombic force acting on ...
Yousang Won, Jeongwoo Lee, Hyunwook Kim, Joon Hak Oh   +3 more
wiley   +1 more source

Contribution of individual excitatory synapses on dendritic spines to electrical signaling

Frontiers in Neuroscience
Dendritic spines, ∼1 μm protrusions from neuronal dendrites that receive most of the excitatory synaptic inputs in the mammalian brain, are widely considered the elementary computational units in the nervous system.
Ju-Yun Weng, Cesar Ceballos, Dejan Zecevic   +2 more
doaj   +1 more source

Reward behavior is regulated by the strength of hippocampus-nucleus accumbens synapses

Nature, 2018
Reward drives motivated behaviours and is essential for survival, and therefore there is strong evolutionary pressure to retain contextual information about rewarding stimuli. This drive may be abnormally strong, such as in addiction, or weak, such as in
T. LeGates, Mark D. Kvarta, Jessica R. Tooley, T. C. Francis, M. Lobo, Meaghan C. Creed, Scott M. Thompson   +6 more
semanticscholar   +1 more source

Spectrally Tuned Floating‐Gate Synapse Based on Blue‐ and Red‐Absorbing Organic Molecules for Wavelength‐Selective Neural Networks and Fashion Image Classifications

Advanced Functional Materials, EarlyView.
The characteristics of a vertical floating gate heterostructure transistor device that exhibits neuromorphic potentiation under visible light illumination are investigated. Due to spectrally‐tuned absorbance properties of each thin film layer and introduction of tunneling dielectric, the device enables wavelength‐selective tuning of synaptic plasticity
Seungme Kang, Jisoo Park, Jinwoong Hong, Jinmin Park, Jeongbo Lee, Hyeonjung Kim, Wonjun Shin, Eva Bestelink, Radu A. Sporea, Seyong Oh, Chung Whan Lee, Yun‐Hi Kim, Hocheon Yoo   +12 more
wiley   +1 more source