Results 231 to 240 of about 460,902 (390)

Suppression of foreign synapses [PDF]

, 1976
Jeremy P. Brockes
openalex   +1 more source

Elevated Apolipoprotein E Expression in Hippocampal Microglia Drives Temporal Lobe Epilepsy Progression

Advanced Science, EarlyView.
In temporal lobe epilepsy, hippocampal APOE is markedly upregulated predominantly in microglia. APOE overexpression in microglia drives TLR4 and cGAS/STING‐dependent neuroinflammation, engages bidirectional crosstalk with neurons and astrocytes, increases neuronal excitability, and perturbs hippocampal lipid metabolism. These findings suggest that APOE‐
Jianwei Shi, Zesheng Li, Xin Sun, Yanfeng Yang, Yumin Luo, Ziang Song, Hengxin Dong, Lei Jin, Jing Xie, Yongzhi Shan, Guoguang Zhao   +10 more
wiley   +1 more source

C4d, a high-affinity LilrB2 ligand, is elevated in Alzheimer's disease and mediates synapse pruning. [PDF]

Proc Natl Acad Sci U S A
Brott BK, Raissi AJ, Micheva KD, Vielmetter J, Mendes MS, Baccus CJ, Huang J, Shatz CJ.   +7 more
europepmc   +1 more source

Identifying Tipping Points during Healthy Brain Aging through Single‐Nucleus Transcriptomic Analysis

Advanced Science, EarlyView.
This study applies single‐nucleus transcriptomics and systems dynamics to uncover nonlinear aging patterns in healthy human brains. By introducing dynamic network biomarker theory, the authors identify a critical tipping point at ages 56–60 during aging, and highlight glial instability as a key mediator.
Peiru Wu, Xuyu Zhao, Zixin Chen, Jingying Huang, Tengteng Dai, Jianxin Zhou, Luyao Xiao, Luonan Chen, Robert Chunhua Zhao, Jiao Wang   +9 more
wiley   +1 more source

GABA_B receptor-mediated potentiation of ventral medial habenula glutamatergic transmission in GABAergic and glutamatergic interpeduncular nucleus neurons. [PDF]

IBRO Neurosci Rep
Stinson HE, Ninan I.
europepmc   +1 more source

The Fusion of Merkel Cell Granules with a Synapse-Like Structure

, 1973
Sow‐Yeh Chen, Stanley Gerson, Julia Meyer   +2 more
openalex   +1 more source

Receptor synapses without synaptic ribbons in the cochlea of the cat. [PDF]

, 1975
RJ Dunn, D.K. Morest
openalex   +1 more source

ZnO Quantum Dots@CsPbBr3 Poly‐Heterocrystalline Film Enables High‐Performance Floating‐Gate Transistor Arrays for Edge Computing

Advanced Science, EarlyView.
The ZnO QDs@CsPbBr3 poly‐heterocrystalline film, featuring a semi‐coherent interface, delivers high electrical conductivity and excellent photoelectric properties. Functioning as a floating gate in photosensitive transistors, it enables high hole storage at 1 V and achieves a conductivity ratio of ≈3.57×105.
Jiajun Xu, Bo Tong, Nian Dai, Tongjian Liu, Zhibo Liu, Dingdong Zhang, Yan Liang, Song Qiu, Lai‐Peng Ma, Jinhong Du   +9 more
wiley   +1 more source

Alterations of Photoreceptor Synaptic Ribbons in the Retina of a Human Patient With Oculocutaneous Albinism Type 1 (OCA1). [PDF]

Invest Ophthalmol Vis Sci
Köller AF, Käsmann-Kellner B, Benseler F, Tschernig T, Löw U, Maxeiner S, Schwarz K, Brose N, Geerling G, Seitz B, Schmitz F.   +10 more
europepmc   +1 more source

ON THE ACTIONS OF COMPOUNDS RELATED TO DOPAMINE AT A NEUROSECRETORY SYNAPSE

, 1976
B. L. Ginsborg, Kathleen Turnbull, C. R. House   +2 more
openalex   +2 more sources