Results 91 to 100 of about 324,242 (283)

Switch to phagocytic microglia by CSFR1 inhibition drives amyloid-beta clearance from glutamatergic terminals rescuing LTP in acute hippocampal slices

Translational Psychiatry
Microglia, traditionally regarded as innate immune cells in the brain, drive neuroinflammation and synaptic dysfunctions in the early phases of Alzheimer disease (AD), acting upstream to Aβ accumulation.
Gaia Piccioni, Nunzia Maisto, Asia d’Ettorre, Georgios Strimpakos, Robert Nisticò, Viviana Triaca, Dalila Mango   +6 more
doaj   +1 more source

Routing Hippocampal Information Flow through Parvalbumin Interneuron Plasticity in Area CA2

Cell Reports, 2019
Summary: The hippocampus is critical for the formation of episodic memory. It is, therefore, important to understand intra-hippocampal circuitry, especially in the often overlooked area CA2.
Kaoutsar Nasrallah, Ludivine Therreau, Vincent Robert, Arthur J.Y. Huang, Thomas J. McHugh, Rebecca A. Piskorowski, Vivien Chevaleyre   +6 more
doaj   +1 more source

Potentiation Decay of Synapses and the Length Distributions of Synfire Chains Self-organized in Recurrent Neural Networks

, 2013
Synfire chains are thought to underlie precisely-timed sequences of spikes observed in various brain regions and across species. How they are formed is not understood. Here we analyze self-organization of synfire chains through the spike-timing dependent
Jin, Dezhe Z., Miller, Aaron
core   +1 more source

Universal Neuromorphic Element: NbOx Memristor with Co‐Existing Volatile, Non‐Volatile, and Threshold Switching

Advanced Functional Materials, EarlyView.
A W/NbOx/Pt memristor demonstrates the coexistence of volatile, non‐volatile, and threshold switching characteristics. Volatile switching serves as a reservoir computing layer, providing dynamic short‐term processing. Non‐volatile switching, stabilized through ISPVA, improves reliable long‐term readout. Threshold switching operates as a leaky integrate
Ungbin Byun, Hyesung Na, Sungjun Kim
wiley   +1 more source

Dopamine release regulation by astrocytes during cerebral ischemia

Neurobiology of Disease, 2013
Brain ischemia triggers excessive release of neurotransmitters that mediate neuronal damage following ischemic injury. The striatum is one of the areas most sensitive to ischemia.
Idaira Oliva, Miriam Fernández, Eduardo D. Martín   +2 more
doaj   +1 more source

Forward Table-Based Presynaptic Event-Triggered Spike-Timing-Dependent Plasticity

, 2016
Spike-timing-dependent plasticity (STDP) incurs both causal and acausal synaptic weight updates, for negative and positive time differences between pre-synaptic and post-synaptic spike events.
Augustine, Charles, Cauwenberghs, Gert, Detorakis, Georgios, IEEE, Joshi, Siddharth, Neftci, Emre, Paul, Somnath, Pedroni, Bruno U, Sheik, Sadique   +8 more
core   +1 more source

A Van der Waals Optoelectronic Synapse with Tunable Positive and Negative Post‐Synaptic Current for Highly Accurate Spiking Neural Networks

Advanced Functional Materials, EarlyView.
A van der Waals optoelectronic synaptic device based on a ReS2/WSe2 heterostructure and oxygen‐treated h‐BN is presented, which enables both positive and negative PSCs through photocarrier polarity reversal. Bidirectional plasticity arises from gate‐tunable band bending and charge trapping‐induced quasi‐doping.
Hyejin Yoon, Soeun Park, Yeong Kwon Kim, Juhwan Baek, Ki Han Kim, Seongil Yun, Hyeonchang Son, Jeongeun Choi, Byung Chul Jang, Dong‐Ho Kang   +9 more
wiley   +1 more source

Altered Short-Term Synaptic Plasticity in Mice Lacking the Metabotropic Glutamate Receptor mGlu7

The Scientific World Journal, 2002
Eight subtypes of metabotropic glutamate (mGlu) receptors have been identified of which two, mGlu5 and mGlu7, are highly expressed at synapses made between CA3 and CA1 pyramidal neurons in the hippocampus.
Trevor J. Bushell, Gilles Sansig, Valerie J. Collett, Herman van der Putten, Graham L. Collingridge   +4 more
doaj   +1 more source

Spectrally Tunable 2D Material‐Based Infrared Photodetectors for Intelligent Optoelectronics

Advanced Functional Materials, EarlyView.
Intelligent optoelectronics through spectral engineering of 2D material‐based infrared photodetectors. Abstract The evolution of intelligent optoelectronic systems is driven by artificial intelligence (AI). However, their practical realization hinges on the ability to dynamically capture and process optical signals across a broad infrared (IR) spectrum.
Junheon Ha, Yingshan Ma, Yong Nam An, Sung‐Un An, Hyeon Hak Jung, Suvi‐Tuuli Varjamo, Jiwon Yoo, Junho Min, Hanvit Kim, Faisal Ahmed, Sang Hoon Chae, Young Min Song, Weiwei Cai, Tawfique Hasan, Zhipei Sun, Dong‐Ho Kang, Hyeon‐Jin Shin, Yunyun Dai, Hoon Hahn Yoon   +18 more
wiley   +1 more source

Maturation of PNN and ErbB4 Signaling in Area CA2 during Adolescence Underlies the Emergence of PV Interneuron Plasticity and Social Memory

Cell Reports, 2019
Summary: Adolescence is a vulnerable period characterized by major cognitive changes. The mechanisms underlying the emergence of new cognitive functions are poorly understood.
Soledad Domínguez, Christophe Clément Rey, Ludivine Therreau, Aurélien Fanton, Dominique Massotte, Laure Verret, Rebecca Ann Piskorowski, Vivien Chevaleyre   +7 more
doaj   +1 more source