Results 101 to 110 of about 571,868 (347)
Proteins Involved in the Trafficking and Functional Synaptic Expression of AMPA and KA Receptors
The Scientific World Journal, 2002 α-Amino-3-hydroxy-5-methylisoxazolepropionate receptors (AMPARs) mediate the majority of fast synaptic transmission in the mammalian central nervous system, play a central role in synapse stabilisation and plasticity, and their prolonged activation is ...
Sarah A. De La Rue, Jeremy M. Henley
doaj +1 more source
Journal of Neural Transplantation and Plasticity, 2018 NMDA ionotropic glutamate receptors (NMDARs) are crucial in activity-dependent synaptic changes and in learning and memory. NMDARs are composed of two GluN1 essential subunits and two regulatory subunits which define their pharmacological and ...
M. V. Baez, M. Cercato, D. Jerusalinsky
semanticscholar +1 more source
UV Laser‐Induced Carbon Microelectrode Arrays for Neuronal Recordings
Advanced Healthcare Materials, EarlyView.Thin‐film electrodes are flexible devices of high conformability and minimal dimensions with attractive properties for in vivo and in vitro bioelectronics. Here, electrodes are developed from parylene films via ultraviolet laser‐induced carbonization.
Fulvia Del Duca +10 more
wiley +1 more source
The developmental stages of synaptic plasticity
The Journal of Physiology, 2013 Abstract The brain is programmed to drive behaviour by precisely wiring the appropriate neuronal circuits. Wiring and rewiring of neuronal circuits largely depends on the orchestrated changes in the strengths of synaptic contacts. Here, we review how the rules of synaptic plasticity change during development of the brain, from birth to independence ...
Helmut W. Kessels, Christian Lohmann
openaire +5 more sources
Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics
Advanced Materials, EarlyView.Harnessing photo‐energy conversion in nanomaterials enables precision theranostics through light‐driven mechanisms such as photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered surface‐enhanced Raman scattering (SERS), and photodynamic processes. This review explores six fundamental principles of photo‐energy conversion, recent
Jingyu Shi +4 more
wiley +1 more source
Translational concepts of mGluR5 in synaptic diseases of the brain
Frontiers in Pharmacology, 2012 The G-protein coupled receptor family of glutamate receptors, termed metabotropic glutamate receptors (mGluRs), are implicated in numerous cellular mechanisms ranging from neural development to the processing of cognitive, sensory, and motor information.
Thomas M Piers +9 more
doaj +1 more source
Neural Computation, 2017 To efficiently learn from feedback, cortical networks need to update synaptic weights on multiple levels of cortical hierarchy. An effective and well-known algorithm for computing such changes in synaptic weights is the error backpropagation algorithm ...
James C. R. Whittington, R. Bogacz
semanticscholar +1 more source
Neuromorphic Light‐Responsive Organic Matter for in Materia Reservoir Computing
Advanced Materials, EarlyView.In this work we show that light‐responsive adaptive organic matter can store and process information at the matter level, and emulate neuromorphic functionalities such as short term memory, long term memory and visual memory. Besides demonstrating that material dynamics can be exploited for spatio‐temporal event detection and motion perception, we show
Federico Ferrarese Lupi +5 more
wiley +1 more source
Translational PsychiatryMicroglia, traditionally regarded as innate immune cells in the brain, drive neuroinflammation and synaptic dysfunctions in the early phases of Alzheimer disease (AD), acting upstream to Aβ accumulation.
Gaia Piccioni +6 more
doaj +1 more source