Baishaoluoshi Decoction Mitigates Post-Stroke Spasticity by Targeting Synaptic Plasticity Through the Nogo-A/NgR Signaling Pathway. [PDF]
Sun X +11 more
europepmc +1 more source
Synaptic plasticity: from chimera states to synchronicity oscillations in multilayer neural networks [PDF]
Peihua Feng, Luoqi Ye
openalex +1 more source
Here, a bioinspired light‐accelerated neuromorphic system that seamlessly links tactile sensing, first‐spike‐timing (FST) encoding, and light–electric synaptic learning. Pressure stimuli trigger FST spikes in dual‐gate PDTFTs, while GaOx/IGZO hetero‐synapses exhibit enhanced memory under optical–electrical co‐activation, enabling spiking neural ...
Dan Cai +9 more
wiley +1 more source
All-optical voltage interrogation for probing synaptic plasticity in vivo. [PDF]
Carolan J +7 more
europepmc +1 more source
Urolithin A alleviates schizophrenic-like behaviors and cognitive impairment in rats through modulation of neuroinflammation, neurogenesis, and synaptic plasticity [PDF]
Zhengyuan Huang +7 more
openalex +1 more source
Correlative Imaging Platform Linking Taste Cell Function to Molecular Identity
A correlative imaging platform is developed to study how individual taste cells respond to different taste qualities. By linking cellular activity with molecular identity and environmental context, dual‐tuned taste cells capable of detecting both sweet and umami stimuli are identified.
Sungho Lee +6 more
wiley +1 more source
BDNF-driven synaptic plasticity requires autocrine matrix metalloproteinase-9 activity. [PDF]
Legutko D +7 more
europepmc +1 more source
Nasal Mucosa‐Derived Extracellular Vesicles as a Systemic Antiaging Intervention
This study shows that nasal mucosa‐derived extracellular vesicles (nmEVs) exert systemic anti‐ageing effects in mice by restoring circadian rhythm, suppressing cellular senescence, and improving cognitive function. In aged human bone marrow mesenchymal stem cells, nmEVs reverse senescence‐associated phenotypes and reactivate core clock gene expression.
Wentao Shi +14 more
wiley +1 more source
Aberrant SUMOylation Restricts the Targetable Cancer Immunopeptidome
Pharmacological SUMOylation inhibition (SUMOi) counteracts tumor immune evasion by unmasking an immunogenic HLA‐I peptide and neoepitope repertoire. By restoring HLA‐I ligand availability through increased antigen processing and presentation, enhanced proteasomal cleavage, and modulated TAP1 peptide affinity, SUMOi boosts tumor immunogenicity ...
Uta M. Demel +19 more
wiley +1 more source

