Results 161 to 170 of about 2,583,688 (361)

Dual mode of synaptic transmission in the avian ciliary ganglion

, 1963
Andrew R. Martin, G. Pilar
openalex   +1 more source

Long‐Lasting Auditory and Vestibular Recovery Following Gene Replacement Therapy in a Novel Usher Syndrome Type 1c Mouse Model

Advanced Science, EarlyView.
This study shows that gene replacement therapy using the AAV2/Anc80L65 virus can successfully restore hearing and balance in Ush1c knockout mice. The treatment leads to lasting improvements in both auditory and vestibular functions, highlighting its potential as a therapeutic approach for genetic hearing loss and vestibular disorders in humans ...
Weinan Du, Jun Huang, Aizhen Zhang, Fangfang Zhao, Tianwen Chen, Quinn M. McDermott, Tony Zheng, Haibo Wang, Rongli Zhang, Xiaolin Zhang, Jerome Allison, Hong Zhu, Wu Zhou, Qing Yin Zheng   +13 more
wiley   +1 more source

The ventro‐basal nucleus of the thalamus: potential fields, synaptic transmission and excitability of both presnyaptic and post‐synaptic components

, 1964
P. Andersen, Charles M. Brooks, J. C. Eccles, T. A. Sears   +3 more
openalex   +2 more sources

The analysis of nonlinear synaptic transmission. [PDF]

, 1977
Howard I. Krausz, W. Otto Friesen
openalex   +1 more source

Muscle‐Derived Small Extracellular Vesicles Mediate Exercise‐Induced Cognitive Protection in Chronic Cerebral Hypoperfusion

Advanced Science, EarlyView.
sEVs have a critical role in orchestrating interorgan crosstalk and mediating exercise‐induced therapeutic effects. Lin et al. demonstrates that sEVs miR‐17/20a‐5p mediates the muscle‐brain crosstalk and emphasizes the central role of mTOR signaling in executing molecular programs that can protect brain health in response to exercise. Abstract Physical
Huawei Lin, Lianhua Yin, Weilin Liu, Rui Li, Tao Jiang, Minguang Yang, Yajun Cao, Sinuo Wang, Yan Yu, Cong Chen, Xiaoqin Guo, Wenju Wang, Huanhuan Liu, Yaling Dai, Jiamin Yan, Yanting Lin, Yanyi Ding, Chendong Ruan, Lei Yang, Tiecheng Wu, Jing Tao, Lidan Chen   +21 more
wiley   +1 more source

The Reconstruction of Peripheral Auditory Circuit: Recent Advances and Future Challenges

Advanced Science, EarlyView.
This paper summarizes the potential of biomaterials, stem cells, and gene editing technologies in the regeneration of inner ear hair cells, spiral ganglion neurons, and inner ear organoids. Challenges and potential developments are discussed and explored.
Zhe Li, Ying Zhang, Zhenyu Xiao, Jieyu Qi   +3 more
wiley   +1 more source

Deciphering Auditory Hyperexcitability in Otogl Mutant Mice Unravels an Auditory Neuropathy Mechanism

Advanced Science, EarlyView.
By investigating auditory hyperexcitability in a mouse model for hereditary deafness, this study identified a subpopulation of afferent neurons of the auditory nerve marked by Otogl expression. Despite their apparently normal hearing, Otogl+/− mice display poor activation of afferent neurons processing loud sounds and an elevation of the middle the ear
Mathilde Gagliardini, Sabrina Mechaussier, Carolina Campos Pina, Monica Morais, Olivier Postal, Philippe Jean, Typhaine Dupont, Amrit Singh‐Estivalet, Shéhanie Udugampolage, Cyril Scandola, Elisabeth Verpy, Baptiste Libé‐Philippot, Talya C. Inbar, Joanna Schwenkgrub, Carla Maria Barbosa Spinola, Raphaël Etournay, Aziz El‐Amraoui, Brice Bathellier, Adeline Mallet, Sedigheh Delmaghani, Fabrice Giraudet, Christine Petit, Boris Gourévitch, Paul Avan, Nicolas Michalski   +24 more
wiley   +1 more source

MANGANESE IONS AND SYNAPTIC TRANSMISSION IN THE SUPERIOR CERVICAL GANGLION OF THE CAT [PDF]

, 1974
Krista Kostial, M. Landeka, B. Slat
openalex   +1 more source

Effects of ACTH4–;10 on synaptic transmission in frog sympathetic ganglion [PDF]

, 1979
Wout Wouters, Joep van den Bercken
openalex   +1 more source

Structural Diversity of Mitochondria in the Neuromuscular System across Development Revealed by 3D Electron Microscopy

Advanced Science, EarlyView.
Mitochondria across the entire neuromuscular system have been comprehensively reconstructed at different developmental stages using 3D electron microscopy. Fundamental structural principles related to synaptic function are preserved across development, and these morphologies are adapted to ensure effective neural circuit function.
J. Alexander Bae, Myung‐kyu Choi, Soungyub Ahn, Gwanho Ko, Daniel T. Choe, Hyunsoo Yim, Ken C. Nguyen, Jinseop S. Kim, David H. Hall, Junho Lee   +9 more
wiley   +1 more source