Results 71 to 80 of about 1,906,626 (299)

Regulation of synaptic connectivity: levels of fasciclin II influence synaptic growth in the Drosophila CNS [PDF]

, 2002
Much of our understanding of synaptogenesis comes from studies that deal with the development of the neuromuscular junction (NMJ). Although well studied, it is not clear how far the NMJ represents an adequate model for the formation of synapses within ...
Baines, Richard A.; id_orcid, Baines, Richard A., Salvaterra, Paul M., Thompson, Annemarie, Bate, Michael, Seugnet, Laurent   +5 more
core  

Synaptic adhesion molecules and excitatory synaptic transmission

, 2017
Synaptic adhesion molecules have been extensively studied for their contribution to the regulation of synapse development through trans-synaptic adhesions.
Hyejin Lee, Eunjoon Kim, Seil Jang
core   +1 more source

Molecular mechanisms controlling synaptic recruitment of GluA4 subunit-containing AMPAreceptors [PDF]

, 2017
Synaptic recruitment of AMPA receptors (AMPARs) represents a key postsynaptic mechanism driving functional development and maturation of glutamatergic synapses.
Coleman, S.K., Taira, T., Keinanen, K., Huupponen, J., Luchkina, N.V., Cai, C., Kivisto, A., Lauri, S.E.   +7 more
core   +1 more source

Potentiation of Schaffer-collateral CA1 synaptic transmission by eEF2K and p38 MAPK mediated mechanisms

Frontiers in Cellular Neuroscience, 2016
The elongation factor 2 kinase (eEF2K), likewise known as CaMKIII, has been demonstrated to be involved in antidepressant responses of NMDA receptor antagonists.
Weiguang Weng, Ying Chen, Man Wang, Yinghan Zhuang, Thomas Behnisch   +4 more
doaj   +1 more source

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

Advanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou, Qiang Qin, Xiqin Li, Hanyu Ding, Chun Xu, Yan He, Qingsong Ye   +6 more
wiley   +1 more source

Age-dependent remodelling of ionotropic signalling in cortical astroglia [PDF]

, 2011
Cortical astrocytes express fast ionotropic receptors for glutamate and ATP, although their role in neurone-glia communication remains controversial.
Lalo, Ulyana, Pankratov, Yuriy, Palygin, Oleg, Verkhratsky, Alexei, Oleg Palygin, Ulyana Lalo, North, Richard Alan, Richard Alan North, Yuriy Pankratov, North, R. Alan, Verkhratsky, Alexei; id_orcid, Alexei Verkhratsky   +11 more
core   +1 more source

Efficient Coding and Energy Efficiency Are Promoted by Balanced Excitatory and Inhibitory Synaptic Currents in Neuronal Network

Frontiers in Cellular Neuroscience, 2018
Selective pressure may drive neural systems to process as much information as possible with the lowest energy cost. Recent experiment evidence revealed that the ratio between synaptic excitation and inhibition (E/I) in local cortex is generally ...
Lianchun Yu, Lianchun Yu, Zhou Shen, Chen Wang, Yuguo Yu   +4 more
doaj   +1 more source

An Adaptive Inhibitory WSe2 Transistor for Retinomorphic In‐Sensor Image Processing

Advanced Functional Materials, EarlyView.
Conventional retinomorphic devices typically require deliberate gate‐bias tuning for each illumination condition. In this paper, we demonstrate an adaptive inhibitory WSe2 transistor that uses photo‐induced regime shift between the subthreshold and accumulation modes to achieve decision‐free, intensity‐adaptive image processing within a single pixel ...
Juhwan Baek, Junhwa Oh, Hyeonjung Kim, Minsik Park, Haein Cho, Jin Young Park, Hyeonchang Son, Taeyun Kim, Sung‐Un An, Yamin Zhang, Hyeon‐Jin Shin, Seyong Oh, Dong‐Ho Kang   +12 more
wiley   +1 more source

Clinical and functional studies of autoimmune disorders of neuromuscular transmission [PDF]

, 2015
Inherited and acquired disorders of the neuromuscular junction are an important cause of muscle weakness and fatigability. In this thesis I focus on the autoimmune disorders of neuromuscular transmission.
Spillane, J
core  

Analog Classification of Human Hand Gestures Exploiting Dendritic Integration With an Organic Artificial Soma

Advanced Functional Materials, EarlyView.
An organic neuromorphic architecture for the classification of human motor behavior is presented and validated. It performs somatic integration by linearly combining the activity from three muscles. An investigation of synaptic weights is presented and discussed in relationship with the classification performance.
Ilenia Sergi, Federico Rondelli, Francesco Torricelli, Federica Velluto, Anna De Salvo, Michele Di Lauro, Luciano Fadiga, Fabio Biscarini   +7 more
wiley   +1 more source