Results 61 to 70 of about 1,821,300 (301)

Pre-post synaptic alignment through neuroligin-1 tunes synaptic transmission efficiency

eLife, 2018
The nanoscale organization of neurotransmitter receptors regarding pre-synaptic release sites is a fundamental determinant of the synaptic transmission amplitude and reliability.
Kalina T Haas, Benjamin Compans, Mathieu Letellier, Thomas M Bartol, Dolors Grillo-Bosch, Terrence J Sejnowski, Matthieu Sainlos, Daniel Choquet, Olivier Thoumine, Eric Hosy   +9 more
doaj   +1 more source

Changes in Synaptic Transmission and Long-term Potentiation Induction as a Possible Mechanism for Learning Disability in an Animal Model of Multiple Sclerosis [PDF]

International Neurourology Journal, 2016
Purpose: Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system. It has been shown that memory deficits is common in patients with MS.
Ghasem Mosayebi, Mohammad Reza Soleyman, Mostafa khalili, Masoumeh Mosleh, Mohammad Reza Palizvan   +4 more
doaj   +1 more source

Contribution of Membrane Lipids to Postsynaptic Protein Organization

Frontiers in Synaptic Neuroscience, 2021
The precise subsynaptic organization of proteins at the postsynaptic membrane controls synaptic transmission. In particular, postsynaptic receptor complexes are concentrated in distinct membrane nanodomains to optimize synaptic signaling.
Manon Westra, Yolanda Gutierrez, Harold D. MacGillavry   +2 more
doaj   +1 more source

Regulation of synaptic connectivity: levels of fasciclin II influence synaptic growth in the Drosophila CNS [PDF]

, 2002
Much of our understanding of synaptogenesis comes from studies that deal with the development of the neuromuscular junction (NMJ). Although well studied, it is not clear how far the NMJ represents an adequate model for the formation of synapses within ...
Baines, Richard A.; id_orcid, Baines, Richard A., Salvaterra, Paul M., Thompson, Annemarie, Bate, Michael, Seugnet, Laurent   +5 more
core  

Intermediate Resistive State in Wafer‐Scale Vertical MoS2 Memristors Through Lateral Silver Filament Growth for Artificial Synapse Applications

Advanced Functional Materials, EarlyView.
In MOCVD MoS2 memristors, a current compliance‐regulated Ag filament mechanism is revealed. The filament ruptures spontaneously during volatile switching, while subsequent growth proceeds vertically through the MoS2 layers and then laterally along the van der Waals gaps during nonvolatile switching.
Yuan Fa, Milan Buttberg, Ke Ran, Rana Walied Ahmad, Dennis Braun, Lukas Völkel, Jimin Lee, Sofía Cruces, Bart Macco, Bárbara Canto, Holger Lerch, Thorsten Wahlbrink, Holger Kalisch, Michael Heuken, Andrei Vescan, Joachim Mayer, Zhenxing Wang, Ilia Valov, Stephan Menzel, Max C. Lemme   +19 more
wiley   +1 more source

Astroglia-Derived BDNF and MSK-1 Mediate Experience- and Diet-Dependent Synaptic Plasticity

Brain Sciences, 2020
Experience- and diet-dependent regulation of synaptic plasticity can underlie beneficial effects of active lifestyle on the aging brain. Our previous results demonstrate a key role for brain-derived neurotrophic factor (BDNF) and MSK1 kinase in ...
Ulyana Lalo, Alexander Bogdanov, Guy W. Moss, Yuriy Pankratov   +3 more
doaj   +1 more source

Optoelectronic Synaptic Devices Using Molecular Telluride Phase‐Change Inks for Three‐Factor Learning

Advanced Functional Materials, EarlyView.
Optoelectronic synaptic devices based on solution‐processed molecular telluride GST‐225 phase‐change inks are demonstrated for three‐factor learning. A global optical signal broadcast through a silicon waveguide induces non‐volatile conductance updates exclusively in locally electrically flagged memristors.
Kevin Portner, Dhananjeya Kumaar, Giacomo Torti, Killian Keller, Till Zellweger, Florian M. Schenk, Christoph Weilenmann, Daniel Chelladurai, Vara Prasad Jonnalagadda, Ghazi Sarwat Syed, Vanessa Wood, Jürg Leuthold, Alexandros Emboras, Maksym Yarema, Mathieu Luisier   +14 more
wiley   +1 more source

Actin maintains synaptic transmission by restraining vesicle release probability

iScience
Summary: Despite decades of pharmacological studies, how the ubiquitous cytoskeletal actin regulates synaptic transmission remains poorly understood. We addressed this issue with a tissue-specific knockout of actin β-isoform or γ-isoform, combined with ...
Xin-Sheng Wu, Zhen Zhang, Yinghui Jin, Afreen Mushtaheed, Ling-Gang Wu   +4 more
doaj   +1 more source

Entorhinal denervation induces homeostatic synaptic scaling of excitatory postsynapses of dentate granule cells in mouse organotypic slice cultures [PDF]

, 2012
Denervation-induced changes in excitatory synaptic strength were studied following entorhinal deafferentation of hippocampal granule cells in mature (≥3 weeks old) mouse organotypic entorhino-hippocampal slice cultures.
Roeper, Jochen, Roeper Jochen, Winkels, Raphael, Denise Becker (179935), Thomas Deller, Thomas Deller (179947), Denise Becker, Jedlička, Peter, Becker Denise, Jochen Roeper, Jedlicka Peter, Winkels Raphael, Andreas Vlachos (47497), Vlachos Andreas, Vlachos, Andreas, Andreas Vlachos, Peter Jedlicka, Jochen Roeper (179944), Becker, Denise, Peter Jedlicka (179938), Raphael Winkels (179941), Deller Thomas, Deller, Thomas, Raphael Winkels   +23 more
core   +1 more source

Achieving High ON State Current through Ferroelectric Polarization‐Dependent Interfacial Resistance Switching in Undoped Orthorhombic HfO2 Films

Advanced Functional Materials, EarlyView.
Ferroelectric tunnel junction devices based on epitaxial undoped ferroelectric HfO2 films demonstrate stable switching endurance of over 106 switching cycles, low write voltages of ±3 V, 16 measured resistance states, and neuromorphic capability.
Markus Hellenbrand, Nuno Estrócio, Ji S. Kim, Babak Bakhit, Marian C. Istrate, Corneliu Ghica, Tiago Rebelo, Nives Strkalj, Abin Varghese, Bernardo Almeida, Luís S. Marques, Bipin Rajendran, Judith L. MacManus‐Driscoll, José P. B. Silva   +13 more
wiley   +1 more source