Results 161 to 170 of about 531,557 (374)

Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine

Advanced Science, EarlyView.
Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang, Feng Gao, Liqun Yu, Haokun Chen, Rongrong Zhu   +4 more
wiley   +1 more source

Synaptin, Na⁺,K⁺ ATPase, LDH, CNPase and cytochrome‐C oxidase in adult rat brain synaptic vesicle fractions [PDF]

, 1978
A. Reeber, G. Vincendon, G. Gombos
openalex   +1 more source

Long Term High‐Salt Diet Induces Cognitive Impairments via Down‐Regulating SHANK1

Advanced Science, EarlyView.
The study identifies a novel mechanistic link between long‐term HS diet and cognitive impairment, wherein PKA/CREB axis inactivation leads to SHANK1 reduction, synaptic damage, and cognitive deficits. Abstract High‐salt (HS) diet is an established risk factor for cognitive impairment, but the underlying mechanisms remain unclear.
Cuiping Guo, Yuanyuan Li, Wensheng Li, Tongrui Wu, Yi Liu, Yacoubou Abdoul Razak Mahaman, Jianzhi Wang, Rong Liu, Wei Liu, Hui Shen, Xiaochuan Wang   +10 more
wiley   +1 more source

Inhibition of endocytosis suppresses the nitric oxide-dependent release of Cl- in retinal amacrine cells.

PLoS ONE, 2018
Our lab has previously shown that nitric oxide (NO) can alter the synaptic response properties of amacrine cells by releasing Cl- from internal acidic compartments.
Vernon K Dunn, Evanna Gleason
doaj   +1 more source

AN ELECTRON MICROSCOPIC CHARACTERIZATION OF CLASSES OF SYNAPTIC VESICLES BY MEANS OF CONTROLLED ALDEHYDE FIXATION [PDF]

, 1970
David Bodian
openalex   +1 more source

Small Extracellular Vesicles Orchestrate Cisplatin‐Induced Ototoxicity: Potential Biomarker and Targets Discovery

Advanced Science, EarlyView.
Cisplatin causes reactive oxygen species accumulation, leading to apoptosis and inflammation in cochlear hair cells. Small extracellular vesicles primarily derived from the damaged hair cells likely contribute to cisplatin‐induced ototoxicity, carrying a variety of microRNAs and proteins.
Jingru Ai, Shasha Zhang, Mingchen Dai, Pei Jiang, Jingyuan Huang, Hairong Xiao, Yanqin Lin, Xujun Tang, Wei Tong, Jun He, Qiuyue Mao, Yintao Wang, Zixuan Ye, Tian Wang, Renjie Chai   +14 more
wiley   +1 more source

LOVIT Is a Putative Vesicular Histamine Transporter Required in Drosophila for Vision

Cell Reports, 2019
Summary: Classical fast neurotransmitters are loaded into synaptic vesicles and concentrated by the action of a specific vesicular transporter before being released from the presynaptic neuron.
Ying Xu, Tao Wang
doaj  

Cholinergic nerve terminals contain ascorbic acid which induces Ca²⁺‐dependent release of acetylcholine and ATP from isolated Torpedo synaptic vesicles [PDF]

, 1979
Irit Pinchasi, Daniel M. Michaelson, Mordechai Sokolovsky   +2 more
openalex   +1 more source

Identification of Schwann Cells in Human Intracranial Arteries: Potential Regulatory Role in Atherosclerotic Plaque Progression

Advanced Science, EarlyView.
Schwann cells may facilitate intracranial plaque progression via neurovascular remodelingcting with vascular smooth muscle cells in atherosclerotic plaques, with the SPP1 ‐ ITGB1 signaling axis mediating this interaction as a novel mechanism. Abstract Intracranial atherosclerosis (ICAS), a common cause of ischemic stroke, remains a therapeutic ...
Zijue Wang, Yangzhige He, Weizhuang Yuan, Yijun Xia, Manqiu Ding, Zhen Chen, Naili Wang, Chao Ma, Xiaoyue Wang, Yan Xu, Weihai Xu   +10 more
wiley   +1 more source

The synaptic vesicle and the cytoskeleton [PDF]

Biochemical Journal, 1987
John H. Walker, D V Agoston
openaire   +3 more sources