This study elucidates a novel role of FGF13 in manipulating neuronal fate via mitochondrial transfer. FGF13 is identified as a mitochondria‐stabilizing protein by interacting with mitochondrial proteins. Under stress, the decrease of neuronal FGF13 fails to retain mitochondria within the cytoplasm, leading to the release of damaged mitochondria to ...
Nanshan Song+15 more
wiley +1 more source
Synapsin I (Protein I), a nerve terminal-specific phosphoprotein. II. Its specific association with synaptic vesicles demonstrated by immunocytochemistry in agarose-embedded synaptosomes. [PDF]
Pietro De Camilli+3 more
openalex +1 more source
Visualization of the Spiral Ganglion Neuron in Vivo Using a Novel 177Lu Nuclear Molecule Label
The study developed and validated a radionuclide‐labeled anti‐VGLUT1 antibody probe for the first nuclear imaging of cochlear spiral ganglion neurons (SGNs) in vivo. This approach may provide aid in screening candidates suitable for CI surgery by quantifying the number of surviving SGNs, and predicting the potential for postoperative hearing ...
Chenyang Kong+11 more
wiley +1 more source
Disappearance and reformation of synaptic vesicle membrane upon transmitter release observed under reversible blockage of membrane retrieval [PDF]
J. H. Koenig, Kazuo Ikeda
openalex +1 more source
Engineered macrophage‐derived exosomes overexpressing GNA12 and GNA13 reprogram glial cells to promote neuroprotection and neural regeneration following SCI. A chitosan‐based thermosensitive hydrogel enables sustained intranasal exosome delivery, bypassing systemic barriers and enhancing therapeutic efficacy.
Yangyang Wang+13 more
wiley +1 more source
Fast axonal transport of foreign synaptic vesicles in squid axoplasm. [PDF]
Trina A. Schroer+2 more
openalex +1 more source
Noninvasive and sensitive detection of tau protein dynamics across developmental stages and APOE genotypes remain a challenge in Alzheimer's disease (AD) research. This study reveals the dynamics of tau secretion in label‐free manner using surface‐enhanced Raman spectroscopy (SERS) and human cerebral organoids (hCOs). This study provides novel insights
Yongjae Jo+11 more
wiley +1 more source
Adaptor protein-3 produces synaptic vesicles that release phasic dopamine. [PDF]
Jain S+10 more
europepmc +1 more source
Depolarization-activated potentiation of the T fiber synapse in the blue crab [PDF]
The blue crab T fiber synapse, associated with the stretch receptor of the swimming leg, has a nonspiking presynaptic element that mediates tonic transmission.
Lin, J.-W., Llinas, R.
core
Synapsin I Is Associated with Cholinergic Nerve Terminals in the Electric Organs of Torpedo, Electrophorus, and Malapterurus and Copurifies with Torpedo Synaptic Vesicles [PDF]
Walter Volknandt+3 more
openalex +1 more source