Results 161 to 170 of about 74,511 (302)

Prioritized docking of synaptic vesicles provided by a rapid recycling pathway. [PDF]

iScience, 2023
Tran V, Silva M, Marty A.
europepmc   +1 more source

New insights into epileptic spasm generation and treatment from the TTX animal model

Epilepsia Open, EarlyView.
Abstract Currently, we have an incomplete understanding of the mechanisms underlying infantile epileptic spasms syndrome (IESS). However, over the past decade, significant efforts have been made to develop IESS animal models to provide much‐needed mechanistic information for therapy development.
John W. Swann, Carlos J. Ballester‐Rosado, Chih‐Hong Lee   +2 more
wiley   +1 more source

LOCALIZATION OF RAB5 TO SYNAPTIC VESICLES IDENTIFIES ENDOSOMAL INTERMEDIATE IN SYNAPTIC VESICLE RECYCLING PATHWAY

, 1994
Fischer von Mollard G, STAHL B, WALCHSOLIMENA C, et al. LOCALIZATION OF RAB5 TO SYNAPTIC VESICLES IDENTIFIES ENDOSOMAL INTERMEDIATE IN SYNAPTIC VESICLE RECYCLING PATHWAY. EUROPEAN JOURNAL OF CELL BIOLOGY.
DECAMILLI, P, JAHN, R, TAKEI, K, SUDHOF, TC, KHOKLATCHEV, A, STAHL, B, WALCHSOLIMENA, C, DANIELS, L, Fischer von Mollard, Gabriele ; https://orcid.org/   +8 more
core  

Status epilepticus: Updates on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Status epilepticus (SE) consists of prolonged, self‐sustaining seizures and is a common neurological emergency that causes respiratory compromise and neuronal injury. Without prompt treatment, the seizures can become resistant to benzodiazepines, leading to the progressive evolution of established, refractory, and super‐refractory SE.
Suchitra Joshi, Jaideep Kapur
wiley   +1 more source

CaV1 and CaV2 calcium channels mediate the release of distinct pools of synaptic vesicles. [PDF]

Elife, 2023
Mueller BD, Merrill SA, Watanabe S, Liu P, Niu L, Singh A, Maldonado-Catala P, Cherry A, Rich MS, Silva M, Maricq AV, Wang ZW, Jorgensen EM.   +12 more
europepmc   +1 more source

Exocytosis of GABAergic synaptic vesicles tracked by real-time three-dimensional microscopy

, 2019
The dynamic balance between excitation and inhibition in synaptic transmission is necessary for proper functions of the brain. Inhibitory synaptic transmission, which is mediated mainly by GABA and glycine, regulates the neuronal excitability. Inhibitory
Lee, Cheuk Long Frank, Fan, Ching Yeung, Park, Chungwon, Park, Hyokeun, Park, Keun Yang   +4 more
core  

Transcriptomic signatures reveal systemic adaptations and immune modulation in response to training and competitive racing in horses

Equine Veterinary Journal, EarlyView.
Abstract Background The molecular mechanisms underlying adaptation to physical exertion and racing stress in horses remain incompletely understood. Peripheral blood transcriptomics offers a minimally invasive method to monitor systemic responses to exercise and identify biomarkers of adaptation or overload. Objectives To evaluate transcriptomic changes
Izabela Dąbrowska, Jowita Grzędzicka‐Agko, Paula Kiełbik, Michał Trela, Olga Witkowska‐Piłaszewicz   +4 more
wiley   +1 more source

Impaired docking and recycling of synaptic vesicles in inherited lysosomal sphingolipidoses. [PDF]

Cell Commun Signal
Zelada D, Saldivia N, Konjeti A, Samano S, Marshall MS, Rebiai R, Sutter P, Zurawski Z, Simchuk D, Muchiri R, van Breemen R, Shin D, Givogri MI, Crocker SJ, Alford S, Bongarzone ER.   +15 more
europepmc   +1 more source

Next‐Generation Surgery: Integrating Artificial Intelligence, Genetic Technologies, Bioengineering and Rehabilitation Into Modern Practices

Exploration, EarlyView.
This graphic abstract depicts the convergence of artificial intelligence, genetic technologies, bioengineering, and rehabilitation as the core pillars of next‐generation surgery. These domains collectively enhance preoperative planning, intraoperative precision, tissue reconstruction, and postoperative recovery, driving a paradigm shift toward ...
Dengxiong Li, Jie Wang, Zhipeng Wang, Ruicheng Wu, Zhouting Tuo, Fanglin Shao, Wenjing Ge, Ziyu Shu, Yubo Yang, Dilinaer Wusiman, Qingxin Yu, Luxia Ye, Alisha Pati‐Alam, Facai Zhang, Koo Han Yoo, Susan Heavey, William C. Cho, Dechao Feng   +17 more
wiley   +1 more source

Multimodal imaging of synaptic vesicles with a single probe. [PDF]

Cell Rep Methods, 2022
An SJ, Stagi M, Gould TJ, Wu Y, Mlodzianoski M, Rivera-Molina F, Toomre D, Strittmatter SM, De Camilli P, Bewersdorf J, Zenisek D.   +10 more
europepmc   +1 more source