Results 61 to 70 of about 531,557 (374)
MethodsX, 2021 Two types of secretory vesicles co-exist at some presynaptic terminals. Clear synaptic vesicles (CSV) release their contents at the synaptic active zone, upon single impulses, while dense-core vesicles (DCV) usually release their contents in the ...
Citlali Trueta
doaj
Nanoscale dynamics of synaptic vesicle trafficking and fusion at the presynaptic active zone
eLife, 2016 The cytomatrix at the active zone (CAZ) is a macromolecular complex that facilitates the supply of release-ready synaptic vesicles to support neurotransmitter release at synapses.
Thirumalini Vaithianathan +3 more
doaj +1 more source
Exploring the functional domain and the target of the tetanus toxin light chain in neurohypophysial terminals [PDF]
, 1994 The tetanus toxin light chain blocks calcium induced vasopressin release from neurohypophysial nerve terminals. Here we show that histidine residue 233 within the putative zinc binding motif of the tetanus toxin light chain is essential for the ...
Binz, T. +7 more
core +1 more source
The Bruchpilot cytomatrix determines the size of the readily releasable pool of synaptic vesicles
Journal of Cell Biology, 2013 Two Bruchpilot isoforms create a stereotypic arrangement of the cytomatrix that defines the size of the readily releasable pool of synaptic vesicles.
T. Matković +15 more
semanticscholar +1 more source
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
FM1-43 reveals membrane recycling in adult inner hair cells of the mammalian cochlea [PDF]
, 2002 Neural transmission of complex sounds demands fast and sustained rates of synaptic release from the primary cochlear receptors, the inner hair cells (IHCs). The cells therefore require efficient membrane recycling.
Ashmore, JF +2 more
core +1 more source
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
Research progress on vesicle cycle and neurological disorders
Journal of Pharmacy & Pharmaceutical Sciences, 2021 Neurons are special polarized cells whose synaptic vesicles release neurotransmitters into the synaptic cleft, acting on postsynaptic receptors and thus transmitting information from presynaptic to postsynaptic states.
Chengcheng Zhang, Li-Juan Zhu, Ce Chen
doaj +1 more source
Preferential localization of a vesicular monoamine transporter to dense core vesicles in PC12 cells. [PDF]
, 1994 Neurons and endocrine cells have two types of secretory vesicle that undergo regulated exocytosis. Large dense core vesicles (LDCVs) store neural peptides whereas small clear synaptic vesicles store classical neurotransmitters such as acetylcholine ...
Edwards, RH +5 more
core
The presynaptic ribbon maintains vesicle populations at the hair cell afferent fiber synapse [PDF]
, 2018 The ribbon is the structural hallmark of cochlear inner hair cell (IHC) afferent synapses, yet its role in information transfer to spiral ganglion neurons (SGNs) remains unclear.
Becker, Lars +8 more
core +2 more sources