The synaptonemal complex stabilizes meiosis in allotetraploid Brassica napus and autotetraploid Arabidopsis thaliana. [PDF]
New PhytolSummary Polyploidy plays a key role in genome evolution and crop improvement. The formation of bivalents rather than multivalents during meiosis of polyploids is essential to ensure meiotic stability and optimal fertility of the species. However, the mechanisms preventing multivalent recombination in polyploids remain obscure.
Zhang Y +9 more
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Centrosome dysfunction associated with somatic expression of the synaptonemal complex protein TEX12 [PDF]
Communications Biology, 2021 Sandhu et al. report that the synaptonemal complex (SC) protein, TEX12, localises to centrosomes independently of the SC during meiosis. They also show that it provokes centrosome amplification in somatic cells, a pathology associated with cancer ...
Sumit Sandhu +8 more
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Kinetic analysis of synaptonemal complex dynamics during meiosis of yeast Saccharomyces cerevisiae reveals biphasic growth and abortive disassembly [PDF]
Frontiers in Cell and Developmental Biology, 2023 The synaptonemal complex (SC) is a dynamic structure formed between chromosomes during meiosis which stabilizes and supports many essential meiotic processes such as pairing and recombination. In budding yeast, Zip1 is a functionally conserved element of
Michael G. Pollard +4 more
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Diversification and recurrent adaptation of the synaptonemal complex in Drosophila. [PDF]
PLoS GeneticsThe synaptonemal complex (SC) is a protein-rich structure essential for meiotic recombination and faithful chromosome segregation. Acting like a zipper to paired homologous chromosomes during early prophase I, the complex is a symmetrical structure where
Rana Zakerzade +9 more
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Synaptonemal complex components promote centromere pairing in pre-meiotic germ cells. [PDF]
PLoS Genetics, 2013 Mitosis and meiosis are two distinct cell division programs. During mitosis, sister chromatids separate, whereas during the first meiotic division, homologous chromosomes pair and then segregate from each other.
Nicolas Christophorou +2 more
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Synaptonemal Complex dimerization regulates chromosome alignment and crossover patterning in meiosis. [PDF]
PLoS Genetics, 2021 During sexual reproduction the parental homologous chromosomes find each other (pair) and align along their lengths by integrating local sequence homology with large-scale contiguity, thereby allowing for precise exchange of genetic information.
Spencer G Gordon +3 more
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Synaptonemal complex analysis of the sex bivalent in goats [PDF]
Genetics Selection Evolution, 1994 Amaral MEJ, Jorge W
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Cytological analysis of MRE11 protein during early meiotic prophase I in Arabidopsis and tomato [PDF]
, 2008 Early recombination nodules (ENs) are multiprotein complexes that are thought to be involved in synapsis and recombination, but little is known about their components or how they may be involved in these events. In this study, we describe the cytological
Anderson, L.K. +6 more
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Meiosis in mice without a synaptonemal complex. [PDF]
PLoS ONE, 2011 The synaptonemal complex (SC) promotes fusion of the homologous chromosomes (synapsis) and crossover recombination events during meiosis. The SC displays an extensive structural conservation between species; however, a few organisms lack SC and execute ...
Anna Kouznetsova +3 more
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Synaptonemal complex components persist at centromeres and are required for homologous centromere pairing in mouse spermatocytes. [PDF]
PLoS Genetics, 2012 Recent studies in simple model organisms have shown that centromere pairing is important for ensuring high-fidelity meiotic chromosome segregation. However, this process and the mechanisms regulating it in higher eukaryotes are unknown.
C Gaston Bisig +6 more
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