Results 11 to 20 of about 284,832 (240)

Meiosis in mice without a synaptonemal complex. [PDF]

open access: yesPLoS ONE, 2011
The synaptonemal complex (SC) promotes fusion of the homologous chromosomes (synapsis) and crossover recombination events during meiosis. The SC displays an extensive structural conservation between species; however, a few organisms lack SC and execute ...
Anna Kouznetsova   +3 more
doaj   +6 more sources

Kinetic analysis of synaptonemal complex dynamics during meiosis of yeast Saccharomyces cerevisiae reveals biphasic growth and abortive disassembly [PDF]

open access: yesFrontiers in Cell and Developmental Biology, 2023
The synaptonemal complex (SC) is a dynamic structure formed between chromosomes during meiosis which stabilizes and supports many essential meiotic processes such as pairing and recombination. In budding yeast, Zip1 is a functionally conserved element of
Michael G. Pollard   +4 more
doaj   +2 more sources

Diversification and recurrent adaptation of the synaptonemal complex in Drosophila. [PDF]

open access: yesPLoS Genetics
The synaptonemal complex (SC) is a protein-rich structure essential for meiotic recombination and faithful chromosome segregation. Acting like a zipper to paired homologous chromosomes during early prophase I, the complex is a symmetrical structure where
Rana Zakerzade   +9 more
doaj   +2 more sources

Synaptonemal complex components promote centromere pairing in pre-meiotic germ cells. [PDF]

open access: goldPLoS Genetics, 2013
Mitosis and meiosis are two distinct cell division programs. During mitosis, sister chromatids separate, whereas during the first meiotic division, homologous chromosomes pair and then segregate from each other.
Nicolas Christophorou   +2 more
doaj   +3 more sources

Synaptonemal Complex dimerization regulates chromosome alignment and crossover patterning in meiosis. [PDF]

open access: yesPLoS Genetics, 2021
During sexual reproduction the parental homologous chromosomes find each other (pair) and align along their lengths by integrating local sequence homology with large-scale contiguity, thereby allowing for precise exchange of genetic information.
Spencer G Gordon   +3 more
doaj   +2 more sources

Synaptonemal complex protein 2 (SYCP2) mediates the association of the centromere with the synaptonemal complex [PDF]

open access: yesProtein & Cell, 2017
Jianrong Feng   +8 more
doaj   +4 more sources

Coupling crossover and synaptonemal complex in meiosis. [PDF]

open access: yesGenes Dev, 2022
During meiosis, a molecular program induces DNA double-strand breaks (DSBs) and their repair by homologous recombination. DSBs can be repaired with or without crossovers. ZMM proteins promote the repair toward crossover. The sites of DSB repair are also sites where the axes of homologous chromosomes are juxtaposed and stabilized, and where a structure ...
Grey C, de Massy B.
europepmc   +4 more sources

Hormad1 mutation disrupts synaptonemal complex formation, recombination, and chromosome segregation in mammalian meiosis. [PDF]

open access: yesPLoS Genetics, 2010
Meiosis is unique to germ cells and essential for reproduction. During the first meiotic division, homologous chromosomes pair, recombine, and form chiasmata.
Yong-Hyun Shin   +8 more
doaj   +1 more source

Mutation of the mouse Syce1 gene disrupts synapsis and suggests a link between synaptonemal complex structural components and DNA repair. [PDF]

open access: yesPLoS Genetics, 2009
In mammals, the synaptonemal complex is a structure required to complete crossover recombination. Although suggested by cytological work, in vivo links between the structural proteins of the synaptonemal complex and the proteins of the recombination ...
Ewelina Bolcun-Filas   +7 more
doaj   +1 more source

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