Kinetic analysis of synaptonemal complex dynamics during meiosis of yeast Saccharomyces cerevisiae reveals biphasic growth and abortive disassembly [PDF]
Frontiers in Cell and Developmental Biology, 2023 The synaptonemal complex (SC) is a dynamic structure formed between chromosomes during meiosis which stabilizes and supports many essential meiotic processes such as pairing and recombination. In budding yeast, Zip1 is a functionally conserved element of
Michael G. Pollard +4 more
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SCFCdc4 ubiquitin ligase regulates synaptonemal complex formation during meiosis [PDF]
Life Sci Alliance, 2020 During meiosis, homologous chromosomes pair to form the synaptonemal complex (SC). This study showed that SCFCdc4 ubiquitin ligase is required for and works with Pch2 AAA+ ATPase for SC assembly. Homologous chromosomes pair with each other during meiosis,
Zhihui Zhu +3 more
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A molecular model for self-assembly of the synaptonemal complex protein SYCE3 [PDF]
Journal of Biological Chemistry, 2019 The synaptonemal complex (SC) is a supramolecular protein assembly that mediates homologous chromosome synapsis during meiosis. This zipper-like structure assembles in a continuous manner between homologous chromosome axes, enforcing a 100-nm separation ...
O. Dunne, O. Davies
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Diversification and recurrent adaptation of the synaptonemal complex in Drosophila. [PDF]
PLoS GeneticsThe synaptonemal complex (SC) is a protein-rich structure essential for meiotic recombination and faithful chromosome segregation. Acting like a zipper to paired homologous chromosomes during early prophase I, the complex is a symmetrical structure where
Rana Zakerzade +9 more
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Chromosome-autonomous feedback down-regulates meiotic DNA break competence upon synaptonemal complex formation [PDF]
Genes & Development, 2020 In this study, Mu et al. set out to elucidate the mechanism underlying double-strand break (DSB) feedback control that arises due to a failure of homolog engagement.
Xiaojing Mu +3 more
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C14ORF39/SIX6OS1 is a constituent of the synaptonemal complex and is essential for mouse fertility
Nature Communications, 2016 The synaptonemal complex is a meiosis-specific proteinaceous structure that supports homologous chromosome pairs during meiosis. Here, the authors show that SIX6OS1 (of previously unknown function) is part of the synaptonemal complex central element and ...
Laura Gómez-H +12 more
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Tracking down the molecular architecture of the synaptonemal complex by expansion microscopy [PDF]
Nat Commun, 2019 The synaptonemal complex (SC) is a meiosis-specific nuclear multiprotein complex that is essential for proper synapsis, recombination and segregation of homologous chromosomes. We combined structured illumination microscopy (SIM) with different expansion
Fabian Zwettler +6 more
semanticscholar +2 more sources
Surface-spreading technique of meiotic cells and immunodetection of synaptonemal complex proteins in teleostean fishes [PDF]
, 2015 Background: Different moderrn methodologies are presently available to analyze meiotic chromosomes. These methods permit investigation of the behavior of chromosomes in the normal complement and of sex and B chromosomes, two special types of chromosomes ...
Cristian Araya‐Jaime +6 more
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Synaptonemal complex analysis in goats carrying the 5/15 Robertsonian translocation [PDF]
Genetics Selection Evolution, 1994 Amaral MEJ, Jorge W
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The novel synaptonemal complex central element SCEP3 interlinks synapsis initiation and crossover formation in Arabidopsis thaliana [PDF]
Heckmann S +10 more
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