Results 31 to 40 of about 284,832 (240)

C14ORF39/SIX6OS1 is a constituent of the synaptonemal complex and is essential for mouse fertility

open access: yesNature Communications, 2016
The synaptonemal complex is a meiosis-specific proteinaceous structure that supports homologous chromosome pairs during meiosis. Here, the authors show that SIX6OS1 (of previously unknown function) is part of the synaptonemal complex central element and ...
Laura Gómez-H   +12 more
doaj   +1 more source

A molecular cell biology toolkit for the study of meiosis in the silkworm Bombyx mori

open access: yesG3: Genes, Genomes, Genetics, 2023
Meiosis is usually described as 4 essential and sequential processes: (1) homolog pairing; (2) synapsis, mediated by the synaptonemal complex; (3) crossing over; and (4) segregation.
Youbin Xiang   +9 more
doaj   +1 more source

Evolutionary history of the mammalian synaptonemal complex [PDF]

open access: yesChromosoma, 2016
The synaptonemal complex (SC), a key structure of meiosis that assembles during prophase I, has been initially described 60 years ago. Since then, the structure has been described in many sexually reproducing organisms. However, the SC protein components were characterized in only few model organisms.
Fraune, J.   +5 more
openaire   +4 more sources

A BIRD´S-EYE VIEW OF CHROMOSOMES DURING MEIOTIC PROPHASE I [PDF]

open access: yesBAG. Journal of Basic and Applied Genetics, 2022
The present review aims to summarize the research carried out in relation to meiosis in birds, especially by observing the protein axes of the chromosomes in prophase I of meiosis. This line of research, initially developed in Argentina, has provided key
Pigozzi M.I.
doaj   +1 more source

A Rado theorem for complex spaces [PDF]

open access: yesarXiv, 2021
We generalize Rado's extension theorem to complex spaces.
arxiv  

Oriented Getzler-Kapranov complexes and framed curves [PDF]

open access: yesarXiv, 2022
In the present paper, we introduce and study oriented Getzler-Kapranov complexes. These complexes are generalizations of S. Merkulov's oriented graph complex. We investigate their relation to the cohomology of moduli spaces of complex and tropical curves, ribbon graph complexes, and motivic structures in string topology.
arxiv  

Human disease locus discovery and mapping to molecular pathways through phylogenetic profiling

open access: yesMolecular Systems Biology, 2013
Genes with common profiles of the presence and absence in disparate genomes tend to function in the same pathway. By mapping all human genes into about 1000 clusters of genes with similar patterns of conservation across eukaryotic phylogeny, we ...
Yuval Tabach   +9 more
doaj   +1 more source

Surveillance of cohesin-supported chromosome structure controls meiotic progression

open access: yesNature Communications, 2020
Meiosis-specific cohesins and the synaptonemal complex are essential for meiotic chromosome structure and function. Here the authors show that continued surveillance of these chromosome structures controls meiotic progression by regulating CHK-2, a ...
Maikel Castellano-Pozo   +6 more
doaj   +1 more source

Pairing of homologous chromosomes in C. elegans meiosis requires DEB-1 - an orthologue of mammalian vinculin

open access: yesNucleus, 2019
During meiosis, homologous chromosomes undergo a dramatic movement in order to correctly align. This is a critical meiotic event but the molecular properties of this ‘chromosomal dance’ still remainunclear.
Jana Rohožková   +4 more
doaj   +1 more source

Relating CAT(0) cubical complexes and flag simplicial complexes [PDF]

open access: yesarXiv, 2020
Given a finite CAT(0) cubical complex, we define a flag simplicial complex associated to it, called the crossing complex. We show that the crossing complex holds much of the combinatorial information of the original cubical complex: for example, hyperplanes in the cubical complex correspond to vertex links in the crossing complex, and the crossing ...
arxiv  

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