Kinetic analysis of synaptonemal complex dynamics during meiosis of yeast Saccharomyces cerevisiae reveals biphasic growth and abortive disassembly [PDF]
Frontiers in Cell and Developmental Biology, 2023 The synaptonemal complex (SC) is a dynamic structure formed between chromosomes during meiosis which stabilizes and supports many essential meiotic processes such as pairing and recombination. In budding yeast, Zip1 is a functionally conserved element of
Michael G. Pollard +4 more
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A new role for the synaptonemal complex in the regulation of meiotic recombination. [PDF]
Genes Dev, 2020 This Outlook discusses Mu et al.’s finding showing that synaptonemal complex (SC) formation between individual chromosomes provides the feedback to down-regulate Spo11 activity, thereby revealing an additional function for the SC.
Hollingsworth NM.
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Diversification and recurrent adaptation of the synaptonemal complex in Drosophila. [PDF]
PLoS GeneticsThe synaptonemal complex (SC) is a protein-rich structure essential for meiotic recombination and faithful chromosome segregation. Acting like a zipper to paired homologous chromosomes during early prophase I, the complex is a symmetrical structure where
Rana Zakerzade +9 more
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Chromosome-autonomous feedback down-regulates meiotic DNA break competence upon synaptonemal complex formation [PDF]
Genes & Development, 2020 In this study, Mu et al. set out to elucidate the mechanism underlying double-strand break (DSB) feedback control that arises due to a failure of homolog engagement.
Xiaojing Mu +3 more
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Correction: Synaptonemal & CO analyzer: a tool for synaptonemal complex and crossover analysis in immunofluorescence images [PDF]
Frontiers in Cell and Developmental BiologyJoaquim Soriano +3 more
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Surface-spreading technique of meiotic cells and immunodetection of synaptonemal complex proteins in teleostean fishes [PDF]
, 2015 Background: Different moderrn methodologies are presently available to analyze meiotic chromosomes. These methods permit investigation of the behavior of chromosomes in the normal complement and of sex and B chromosomes, two special types of chromosomes ...
Cristian Araya‐Jaime +6 more
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Synaptonemal complex analysis in goats carrying the 5/15 Robertsonian translocation [PDF]
Genetics Selection Evolution, 1994 Amaral MEJ, Jorge W
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The novel synaptonemal complex central element SCEP3 interlinks synapsis initiation and crossover formation in Arabidopsis thaliana [PDF]
Heckmann S +10 more
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The synaptonemal complex aligns meiotic chromosomes by wetting. [PDF]
Sci AdvGordon SG +5 more
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Meiotic Chromosome Structure, the Synaptonemal Complex, and Infertility.
Annual review of genomics and human genetics (Print), 2023 In meiosis, homologous chromosome synapsis is mediated by a supramolecular protein structure, the synaptonemal complex (SC), that assembles between homologous chromosome axes.
I. Adams, O. Davies
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