Results 121 to 130 of about 11,302 (215)

Unraveling the Role of Ensheathing Cells and Perineural Fibroblasts in Olfactory Neurogenesis

Glia, Volume 73, Issue 12, Page 2407-2426, December 2025.
Main Points DEOs are similar to satellite glial cells. DECs react to neuronal injury by promoting lipid metabolism, but do not proliferate. ECs reduce gap junctions upon neuronal injury. Perineural fibroblasts also contribute to the injury response. ABSTRACT During development and following injury‐induced neurogenesis, olfactory ensheathing cells (OECs)
Katja Senf, Sandor Nietzsche, Martin Westermann, Eva M. Neuhaus   +3 more
wiley   +1 more source

A tumorsejtek szabályozási zavarai - a diagnosis és a terápia alapja = Disturbances in cancer cell regulation - a basis to design diagnosis and therapy [PDF]

, 2009
A project a daganatok viselkedését befolyásoló olyan molekuláris történésekkel foglalkozott, amelyek felhasználhatók diagnosztikai markerként vagy terápiás célpontként. Ennek eredményeként mutattuk ki NSCLC-ben az EGFR mutációk jellegét és gyakoriságát,
Kopper, László, Kovalszky, Ilona, Matolcsy, András, Nagy, Péter, Paku, Sándor, Peták, István, Sebestyén, Anna   +6 more
core  

Association Between Serum Syndecan 1 Levels and Metabolic Syndrome Parameters: A Comparative Cross‐Sectional Study

Endocrinology, Diabetes &Metabolism, Volume 8, Issue 6, November 2025.
The results revealed that men in the MetS+ HTN+ ALT+ group had significantly higher serum SDC1 levels than women (20.19 ± 10.56 vs. 11.82 ± 5.09 ng/mL, p = 0.020). Furthermore, in both the total study sample and the MetS+ HTN+ ALT+ group, SDC1 concentrations were positively correlated with diastolic blood pressure (r = 0.256, p = 0.021; r = 0.463, p ...
Shima Tavalaie, Saeed Darroudi, Niloofar Shabani, Artemis AzadAra, Ali Mottaghi‐Moghaddam, Mohammad Kalate Rahmani, Maryam Mohammadi‐Bajgiran, Gordon A. Ferns, Maryam Saberi‐Karimian, Majid Ghayour‐Mobarhan   +9 more
wiley   +1 more source

Heparan Sulfate: A Ubiquitous Glycosaminoglycan with Multiple Roles in Immunity

, 2015
Heparan sulfate (HS) is a highly acidic linear polysaccharide with a very variable structure. It is ubiquitously expressed on cell surfaces and in the extracellular matrix and basement membrane of mammalian tissues.
Parish, Christopher, Simon Davis, David Anak   +1 more
core   +1 more source

Immunomodulatory Mechanisms of Chronic Wound Healing: Translational and Clinical Relevance

MedComm, Volume 6, Issue 11, November 2025.
This graphical abstract illustrates the immunomodulation of chronic wounds through various therapeutic approaches aimed at regulating the immune response to promote healing. ABSTRACT Chronic wounds—such as diabetic foot ulcers (DFUs), pressure ulcers (PUs), and venous leg ulcers (VLUs)—pose a serious clinical challenge due to their prolonged ...
Mahrukh Riaz, Muhammad Zohaib Iqbal, Agnes S. Klar, Thomas Biedermann   +3 more
wiley   +1 more source

Serum expression of ESM-1 and Syndecan-1 and its relationship with disease severity in children with Mycoplasma pneumoniae pneumonia

Italian Journal of Pediatrics
Background This study aim to investigate the role of endothelial damage in the pathogenesis of Mycoplasma pneumoniae pneumonia (MPP) by comparing serum levels of endothelial cell-specific molecule 1 (ESM-1) and Syndecan-1 in patients with varying degrees
Yanjuan Yu, Yanyan Su, Xiuhong Jin, Xiangfeng Zhang, Yeran Yang, Yuelin Shen   +5 more
doaj   +1 more source

Comprehensive analysis of extracellular matrix remodelling via cyclophilin inhibition in human models of alcohol‐related liver fibrosis

British Journal of Pharmacology, Volume 182, Issue 22, Page 5647-5669, November 2025.
Background and Purpose Chronic liver disease and hepatic fibrosis constitute a threat to global health. Clinical translation of preclinical research has been limited, highlighting an urgent need for novel treatments. Cyclophilin inhibitors have shown beneficial effects in liver disease; however, the underlying mechanism of action and the effect across ...
Una Rastovic, Sara Campinoti, Lai Wei, Bruna Almeida, Sergio Francesco Bozzano, Ramin Amiri, Nicola Harris, Omolola Ajayi, Tsin Shue Koay, Caoimhe Kerins, Fiona N. Kenny, Ane Zamalloa, Lissette Adofina, Rosa Miquel, Yoh Zen, Parthi Srinivasan, Krishna Menon, Nigel Heaton, Camilla Luni, Eileen Gentleman, Tanya Shaw, Daren Ure, Shilpa Chokshi, Luca Urbani, Elena Palma   +24 more
wiley   +1 more source

Reduction of syndecan‐1 expression during lip carcinogenesis

Journal of Oral Pathology & Medicine, 2009
Background:  Actinic cheilitis (AC) is an oral pre‐cancerous lesion that sometimes develops into lip squamous cell carcinoma (SCC). Syndecan‐1, a transmembrane heparan sulfate proteoglycan, modulates cell‐proliferation, adhesion, migration and angiogenesis.
Martinez, A., Spencer, M. L., Brethauer, U., Grez, P., Marchesani, F. J., Rojas, I. G.   +5 more
openaire   +5 more sources

Changes in microcirculation variables in an acute endotoxaemic equine model

Equine Veterinary Journal, Volume 57, Issue 6, Page 1623-1634, November 2025.
Abstract Background Microcirculation is the essential link between macrocirculation and cellular metabolism. Objectives To test our hypotheses that microcirculation variables will show a heterogeneous flow pattern during experimental endotoxaemia, and that fluid therapy and noradrenaline (NA) infusion will normalise altered microcirculation variables ...
Philipp K. Sauter, Barbara Steblaj, Sabine B. R. Kästner, Franz J. Söbbeler, Julia K. Reiners, Annette P. N. Kutter, Alvaro J. Gutiérrez Bautitsta, Stephan Neudeck   +7 more
wiley   +1 more source

Reed-Sternberg Cells of Classical Hodgkin's Disease React With the Plasma Cell-Specific Monoclonal Antibody B-B4 and Express Human Syndecan-1 [PDF]

, 1997
Antonino Carbone, Annunziata Gloghini, Valter Gattei, Massimo Degan, Salvatore Improta, Donatella Aldinucci, Vincenzo Canzonieri, Tiziana Perin, Rachele Volpe, Gianluca Gaïdano, Vittorina Zagonel, Antonio Pinto   +11 more
openalex   +1 more source