Results 101 to 110 of about 107,687,715 (215)

Immunohistochemical expression of heparanase isoforms and syndecan-1 proteins in colorectal adenomas

European Journal of Histochemistry, 2016
The proteoglycan syndecan-1 and the endoglucuronidases heparanase-1 and heparanase-2 are involved in molecular pathways that deregulate cell adhesion during carcinogenesis.
J. Waisberg, T.R. Theodoro, L.L. Matos, F.B. Orlandi, R.L. Serrano, G.T. Saba, M.A.S. Pinhal   +6 more
doaj   +1 more source

Proteomic signatures of equine dental tooth tissues in ageing and disease

Equine Veterinary Journal, Volume 58, Issue 6, Page 1552-1569, November 2026.
Abstract Background Ageing and dental disease in horses lead to structural and functional deterioration of dental tissues, yet their molecular signatures remain poorly characterised. Understanding how these processes alter the protein composition of enamel, dentin, cementum and pulp is essential for improving equine oral health and identifying ...
Anders Jensen, Danae Emilie Zambouli, Iris Gringel, Zoe Nugent, Kazuhiro Yamamoto, Lee Cooper, Andrew J. Peffers, Guido Rocchigiani, Mandy J. Peffers   +8 more
wiley   +1 more source

Expression of Syndecan-1 (Cd138) in Nasopharyngeal Carcinoma Is Correlated with Advanced Stage and Poor Prognosis

, 2008
Nasopharyngeal carcinoma (NPC) is an important Epstein-Barr virus- associated head and neck malignancy in Taiwan. Syndecan-1 (CD138) is involved in growth, differentiation, invasiveness, and metastatic potential of certain tumors, but its expression in ...
陳志榮;歐大諒, CHEN, CHI-LONG;OU, DA-LIANG   +1 more
core  

Prognostička vrijednost izraženosti sindekana-1 i sindekana-2 u adenokarcinomu prostate [Prognostic value of syndecan-1 and syndecan-2 in prostatic adenocarcinoma] [PDF]

, 2011
In this study, we analyzed the expression and prognostic value of syndecan-1 and-2 in prostate cancer. Hypothesis of this study was that the increased expression of syndecan-1 and 2 in prostate cancer is associated with poorer disease prognosis.
Popović, Alek
core   +1 more source

Immunohistochemical analysis of syndecan-1 in leukoplakia and oral submucous fibrosis

Dental Research Journal, 2013
Background: Syndecan-1 is abundant in normal tissues and reduced in squamous cell carcinomas. Leukoplakia and oral submucous fibrosis (OSF) are oral pre-cancerous disorders that have potential for malignant transformation.
Sushant S Kamat, G S Kumar, Ajit V Koshy
doaj   +1 more source

Exosomes in Cancer: The Biology, Function, Diagnosis, and Therapy

MedComm, Volume 7, Issue 11, November 2026.
Tumor‐derived exosomes and nonmembranous extracellular nanoparticles (exomeres/supermeres) constitute a heterogeneous communication network that drives cancer progression. By shuttling functional biomolecules across tissue‐specific barriers, these nanoparticles orchestrate local microenvironmental remodeling, immune suppression, premetastatic niche ...
Jun Wu, Lei Wu, Kang Yang, Kang Xie, Tao Lu, Tiangxiang Huang, Dengfeng Wan, Tao Song, Longbo Zhang   +8 more
wiley   +1 more source

Syndecan-1: a key player in health and disease

Immunogenetics
Syndecan-1 (SDC-1) is a transmembrane protein localized on the basolateral surface of epithelial cells, encompassing a core protein with heparin sulfate and chondroitin sulfate glycosaminoglycan side chains. SDC-1 is involved in a panoply of cellular mechanisms including cell-to-cell adhesion, extracellular matrix interactions, cell cycle modulation ...
Lara, Diab, Sahar, Al Kattar, Naim, Oueini, Jihad, Hawi, Antoine, Chrabieh, Laura, Dosh, Rosalyn, Jurjus, Angelo, Leone, Abdo, Jurjus   +8 more
openaire   +3 more sources

Synthesis and distribution of Syndecan-1 under shear stress.

, 2014
(A) Immunofluorescent images show that shear stress induces the syndecan-1 increase after 24 h of shear exposure. (B) MFI, (C) Coverage, and (D) Radial distribution of syndecan-1.
John M. Tarbell (144466), Ye Zeng (144461)   +1 more
core   +1 more source

Role of Syndecan-1 in Peritoneal Dialysis and Peritonitis [PDF]

, 2014
Chronic peritonitis contributes to technique failure in peritoneal dialysis (PD), an effective replacement therapy for chronic kidney failure. Staphylococcus aureus infection is one of the most common causes of peritonitis in PD.
Kowalewska, Paulina M
core   +1 more source

Redefining CHI3L1: Therapeutic Opportunities at the Crossroads of Immune Suppression and Disease Progression

Medicinal Research Reviews, Volume 46, Issue 6, Page 1897-1921, November 2026.
ABSTRACT Chitinase‐3‐like‐1 (CHI3L1, also known as YKL‐40) has been recognized as a biomarker of inflammation and tissue remodeling and has now emerged as a pseudoenzymatic immune checkpoint. Recent structural, immunological, and translational studies redefine it as an active regulator of immune suppression rather than a passive disease marker. Despite
Kirti Upmanyu, Saurabh Upadhyay, Moustafa T. Gabr   +2 more
wiley   +1 more source