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Syndecan‐1 expression in prostate cancer and its value as biomarker for disease progression
Fadi Brimo +4 more
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Proteolytic Remodeling of the Synaptic Cell Adhesion Molecules (CAMs) by Metzincins in Synaptic Plasticity [PDF]
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PRDM1 expression levels in marginal zone lymphoma and lymphoplasmacytic lymphoma [PDF]
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Syndecan-1 in liver pathophysiology
American Journal of Physiology-Cell Physiology, 2022Syndecan-1 (SDC-1) is a heparan sulfate (HS)/chondroitin sulfate proteoglycan (PG) of the cell surface and the extracellular matrix (ECM), which regulates a broad spectrum of physiological and pathological processes such as cell proliferation, migration, inflammation, matrix remodeling, wound healing, and tumorigenesis. Syndecan-1 represents the major
Andrea Reszegi +4 more
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The role of actomyosin in the regulation of syndecan-1 in hyperosmosis
Biochimica et Biophysica Acta (BBA) - General Subjects, 2021The endothelial glycocalyx is susceptible to high concentration of glucose and sodium in the blood. These challenges often involve an increase in osmotic pressure which may independently alters the glycocalyx components. The glycocalyx anchors on the cell membrane via core proteins that link with the actin cytoskeleton.
Li, W, Wang, W
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Syndecan-1 in B lymphoid malignancies
Annals of Hematology, 2002Syndecans are heparan sulfate-bearing proteoglycans that are found on the surface of most cells. Syndecan-1 is expressed predominantly on epithelia, but is also present on pre-B cells and plasma cells. The syndecans act to bind various effector molecules via their heparan sulfate chains, including both soluble and insoluble molecules within the ...
Magne Børset, Ralph D. Sanderson
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Impaired arteriogenesis in syndecan-1−/− mice
Journal of Surgical Research, 2015Collateral artery development (arteriogenesis) is an important compensatory response to arterial occlusion caused by atherosclerosis. The heparan sulfate proteoglycan syndecan-1 (sdc1) has previously been shown to affect the response to arterial injury but has yet been studied in arteriogenesis.
Gale L. Tang, Kevin Weitz
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Involvement of Syndecan-1 and Heparanase in Cancer and Inflammation
2020The cell surface heparan sulfate proteoglycan Syndecan-1 acts as an important co-receptor for receptor tyrosine kinases and chemokine receptors, and as an adhesion receptor for structural glycoproteins of the extracellular matrix. It serves as a substrate for heparanase, an endo-β-glucuronidase that degrades specific domains of heparan sulfate ...
Felipe C O B Teixeira +2 more
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Syndecan-1 in the Tumor Microenvironment
2020Syndecan-1 along with the other three syndecan proteins is present in the varied components of the tumor microenvironment: fibroblasts, inflammatory tumor immunity-associated cells, vessels, and extracellular matrix. Epithelial and non-epithelial tumors may show stromal syndecans.
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