Acceleration of epithelial cell syndecan-1 shedding by anthrax hemolytic virulence factors. [PDF]
Popova TG +6 more
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Association of serum syndecan-1 concentrations with albuminuria in type 2 diabetes. [PDF]
Kakutani Y +6 more
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RBT-1, a "preconditioning" agent, mitigates syndecan-1 shedding in patients undergoing "on pump" cardiac surgery and following experimental AKI. [PDF]
Johnson ACM, Zager RA.
europepmc +1 more source
Serum matrix metalloproteinase-7, Syndecan-1, and CA 19-9 as a biomarker panel for diagnosis of pancreatic ductal adenocarcinoma. [PDF]
Yablecovitch D +18 more
europepmc +1 more source
Diagnostic value of syndecan-1 for coronary artery lesions and correlation analysis of laboratory indicators in Kawasaki disease patients. [PDF]
Dai L +6 more
europepmc +1 more source
Yellow fever disease severity and endothelial dysfunction are associated with elevated serum levels of viral NS1 protein and syndecan-1. [PDF]
de Sousa FTG +16 more
europepmc +1 more source
The Differentiation Potential of Apical Papilla Cells in Relation to Tenascin-C and Syndecan-1 Expression and Their Potential Role in Regeneration. [PDF]
Kodonas K +3 more
europepmc +1 more source
Molecular Functions of Syndecan-1 in Disease [PDF]
Syndecan-1 is a cell surface heparan sulfate proteoglycan that binds to many mediators of disease pathogenesis. Through these molecular interactions, syndecan-1 can modulate leukocyte recruitment, cancer cell proliferation and invasion, angiogenesis, microbial attachment and entry, host defense mechanisms, and matrix remodeling.
Pyong Woo Park, Rafael S Aquino
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Syndecan-1 in liver pathophysiology
American Journal of Physiology-Cell Physiology, 2022Syndecan-1 (SDC-1) is a heparan sulfate (HS)/chondroitin sulfate proteoglycan (PG) of the cell surface and the extracellular matrix (ECM), which regulates a broad spectrum of physiological and pathological processes such as cell proliferation, migration, inflammation, matrix remodeling, wound healing, and tumorigenesis. Syndecan-1 represents the major
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The role of actomyosin in the regulation of syndecan-1 in hyperosmosis
Biochimica et Biophysica Acta (BBA) - General Subjects, 2021The endothelial glycocalyx is susceptible to high concentration of glucose and sodium in the blood. These challenges often involve an increase in osmotic pressure which may independently alters the glycocalyx components. The glycocalyx anchors on the cell membrane via core proteins that link with the actin cytoskeleton.
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