Results 31 to 40 of about 26,690 (238)

Top coal caving mining technique in thick coal seam beneath the earth dam

International Journal of Mining Science and Technology, 2017
It is important to study the mining technology under structures for raising the coal resources recovery ratio. Based on the geological and mining conditions, the top coal caving harmonic mining technique in thick coal seam beneath the earth dam was put ...
Wenbing Guo, Yi Tan, Erhu Bai
doaj   +1 more source

Effect of Sequential Inoculation of Tetragenococcus halophilus and Wickerhamomyces anomalus on the Flavour Formation of Early-Stage Moromi Fermented at a Lower Temperature

Foods, 2023
Microbial inoculation in moromi fermentation has a great influence on the physicochemical and flavour properties of soy sauces. This work investigated the effect of inoculating Tetragenococcus halophilus and Wickerhamomyces anomalus on the flavour ...
Xinzhi Li, Xinyu Xu, Changzheng Wu, Xing Tong, Shiyi Ou   +4 more
doaj   +1 more source

A schematic of NB synergism (A) and additive synergism (B).

, 2014
Response for AE curve = effect of drug 1 alone+effect of drug 2 alone. The maximal difference between peak value and endpoints of NB curves determines the maximum NB synergism.
John H. Byrne (145197), Paul Smolen (28624), Douglas A. Baxter (145196), Yili Zhang (540283)   +3 more
core   +1 more source

PARP1 expression drives the synergistic antitumor activity of trabectedin and PARP1 inhibitors in sarcoma preclinical models

Molecular Cancer, 2017
Background Enhancing the antitumor activity of the DNA-damaging drugs is an attractive strategy to improve current treatment options. Trabectedin is an isoquinoline alkylating agent with a peculiar mechanism of action.
Ymera Pignochino, Federica Capozzi, Lorenzo D’Ambrosio, Carmine Dell’Aglio, Marco Basiricò, Marta Canta, Annalisa Lorenzato, Francesca Vignolo Lutati, Sandra Aliberti, Erica Palesandro, Paola Boccone, Danilo Galizia, Sara Miano, Giulia Chiabotto, Lucia Napione, Loretta Gammaitoni, Dario Sangiolo, Maria Serena Benassi, Barbara Pasini, Giovanna Chiorino, Massimo Aglietta, Giovanni Grignani   +21 more
doaj   +1 more source

Cytotoxic Marine Alkaloid 3,10-Dibromofascaplysin Induces Apoptosis and Synergizes with Cytarabine Resulting in Leukemia Cell Death

Marine Drugs, 2021
Myeloid leukemia is a hematologic neoplasia characterized by a clonal proliferation of hematopoietic stem cell progenitors. Patient prognosis varies depending on the subtype of leukemia as well as eligibility for intensive treatment regimens and ...
Pavel Spirin, Elena Shyrokova, Timofey Lebedev, Elmira Vagapova, Polina Smirnova, Alexey Kantemirov, Sergey A. Dyshlovoy, Gunhild von Amsberg, Maxim Zhidkov, Vladimir Prassolov   +9 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Silver Nanoparticles Enhance Antimicrobial Efficacy of Antibiotics and Restore That Efficacy against the Melioidosis Pathogen

Antibiotics, 2021
Melioidosis is an infectious disease caused by Gram-negative bacillus bacteria Burkholderia pseudomallei. Due to the emerging resistance of B. pseudomallei to antibiotics including ceftazidime (CAZ), the development of novel antibiotics and alternative ...
Sathit Malawong, Saengrawee Thammawithan, Pawinee Sirithongsuk, Sakda Daduang, Sompong Klaynongsruang, Pamela T. Wong, Rina Patramanon   +6 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Tribo-corrosion mechanisms of stainless steel in soft drinks [PDF]

, 2010
Tribo-corrosion mechanisms of 316L Stainless Steel in slurries containing common household soft drinks have been studied through investigating the micro-abrasion-corrosion performance using a ball and disk apparatus which has been modified to measure the
Stack, M.M., Hodge, C.
core   +4 more sources

IN VITRO COMBINATION OF SIX ANTIBACTERIAL ASSOCIATIONS AGAINST ENTEROBACTERALES ISOLATES PRODUCING KPC OR NDM WITH INTRINSIC OR ACQUIRED RESISTANCE TO POLYMYXIN B

Brazilian Journal of Infectious Diseases
Introduction/Objectives: Therapeutic alternatives for infections caused by Gram-negative bacilli of the order Enterobacterales producing KPC or NDM (E-KPC/NDM) and resistant to polymyxins are virtually nonexistent; therefore, combining antibacterial ...
Lucas Guilherme Toshio Takeuti Wada, Bruna Leticia dos Santos Vinha, Monica de Souza Ferreira de Mattos, Letícia de Andrade Cunha, César Helbel, Christine Eiko Ueno, Josy Anne Silva, Maria Cristina Bronharo Tognim   +7 more
doaj   +1 more source